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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide structure

CAS No.: 654-62-6

Chemical Name:: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

Synonyms: I7C;NSC 44625;Trifluoromethyldisulfonamide;Bendroflumethiazide EP Impurity;Bendroflumethiazide EP Impurity A;Bendroflumethiazide impurity A CRS;4-Amino-6-(trifluoromethyl)benzene-;2,4-Disulfamyl-5-trifluoromethylaniline;4-Amino-6-(trifluoromethyl)benzene-1,3-d;3-(4-methylphenyl)sulfonylpropane-1,2-diol

CBNumber:: CB5693012

Molecular Formula:: C7H8F3N3O4S2

Molecular Weight:: 319.28

MDL Number:: MFCD00197629

MOL File:: 654-62-6.mol

Last updated:2025-10-26 21:25:35

Product description	Number	Pack Size	Price
Bendroflumethiazide impurity A European Pharmacopoeia (EP) Reference Standard	Y0000564	5 mg	$156
2,4-Disulfamyl-5-trifluoromethylaniline United States Pharmacopeia (USP) Reference Standard	1223005	50mg	$1300
Bendroflumethiazide impurity A European Pharmacopoeia (EP) Reference Standard	Y0000564	y0000564	$153
2,4-Disulfamyl-5-trifluoromethylaniline	D493580	1g	$135
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide	FA29652	10g	$60
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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Properties

Melting point	241-246 °C
Boiling point	562.8±60.0 °C(Predicted)
Density	1.743±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	9.14±0.60(Predicted)
form	Solid
color	White to Off-White
BRN	1164542
InChI	InChI=1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17)
InChIKey	KRVABEGPNKGLOT-UHFFFAOYSA-N
SMILES	C1(S(N)(=O)=O)=C(C(F)(F)F)C=C(N)C(S(N)(=O)=O)=C1
CAS DataBase Reference	654-62-6(CAS DataBase Reference)
FDA UNII	YBN90877RI
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	2935909550

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0000564	Bendroflumethiazide impurity A European Pharmacopoeia (EP) Reference Standard	654-62-6	5 mg	$156	2025-07-31	Buy
Sigma-Aldrich	1223005	2,4-Disulfamyl-5-trifluoromethylaniline United States Pharmacopeia (USP) Reference Standard	654-62-6	50mg	$1300	2025-07-31	Buy
Sigma-Aldrich	Y0000564	Bendroflumethiazide impurity A European Pharmacopoeia (EP) Reference Standard	654-62-6	y0000564	$153	2024-03-01	Buy
TRC	D493580	2,4-Disulfamyl-5-trifluoromethylaniline	654-62-6	1g	$135	2021-12-16	Buy
Biosynth Carbosynth	FA29652	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide	654-62-6	10g	$60	2021-12-16	Buy

Product number	Packaging	Price	Buy
Y0000564	5 mg	$156	Buy
1223005	50mg	$1300	Buy
Y0000564	y0000564	$153	Buy
D493580	1g	$135	Buy
FA29652	10g	$60	Buy

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Chemical Properties,Uses,Production

Chemical Properties

Crystallizes. Melting point 242°C.

Uses

2,4-Disulfamyl-5-trifluoromethylaniline is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. Metabolite of hydroflumethazide, a diuretic.

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Preparation Products And Raw materials

Raw materials

3-Nitrobenzotrifluoride Benzotrifluoride Benzotrichloride

Preparation Products

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Suppliers

Global( 113)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8830	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11819	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20284	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58

Supplier	Advantage
NINGBO INNO PHARMCHEM CO., LTD.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58

View Lastest Price from 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-10-26	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide 654-62-6	US $40.00-106.00 / mg		98.58%	10g	TargetMol Chemicals Inc.
	2020-02-17	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide 654-62-6	US $1.00 / KG	1KG	99%	200kgs	Career Henan Chemical Co

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
654-62-6
US $40.00-106.00 / mg
98.58%
TargetMol Chemicals Inc.

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
654-62-6
US $1.00 / KG
99%
Career Henan Chemical Co

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Spectrum

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide(654-62-6)¹HNMR

654-62-6(4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide)Related Search:

3-Aminobenzenesulfonamide ALTRENOGEST 3-(Trifluoromethyl)benzoic acid Benzenesulfonamide Sulfanilamide

Phenylmethylsulfonyl fluoride Glycine 2-(Trifluoromethyl)benzaldehyde 3-(Trifluoromethyl)benzaldehyde 4'-(Trifluoromethyl)acetophenone

N,N-Dimethyl-1,4-phenylenediamine Tris(hydroxymethyl)aminomethane Benzene BENDROFLUMETHIAZIDE penflutizide

flumethiazide HYDROFLUMETHIAZIDE 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

1of4

2,4-Disulfamyl-5-Trifluoromethylaniline (50 mg) 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide technical, >=96% (HPLC) 1,3-Benzenedisulfonamide, 4-amino-6-(trifluoromethyl)- (9CI) I7C 4-Amino-6-trifluoromethyl-1,3-benzenedisul-famide 2-AMINO-4-TRIFLUOROMETHYLBENZENE-1,5-DISULFONAMIDE 1,3-Benzenedisulfonamide, 4-amino-6-(trifluoromethyl)- 5-amino-α,α,α-trifluorotoluene-2,4-disulfonamide 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonami 4-AMINO-6-(TRIFLUOROMETHYL)BENZENE-1,3-DISULFONAMIDE TECHN. 96% 5-amino-α,α,α-trifluorotoluene-2,4-disulphonamide 4-azanyl-6-(trifluoromethyl)benzene-1,3-disulfonamide 2,4-Disulfamyl-5-trifluoromethylaniline (30 mg) 4-AMINO-6-(TRIFLUOROMETHYL)-1,3-BENZENEDISULFONAMIDE 4-AMINO-6-(TRIFLUOROMETHYL)BENZENE-1,3-DISULFONAMIDE 2-AMINO-4-TRIFLUOROMETHYL-1,5-BENZENDISULFONAMIDE 2-AMINO-4-TRIFLUOROMETHYL-1,5-BENZENEDISULFONAMIDE 2-AMINO-4-TRIFLUOROMETHYL-1,5-BENZENEDISULPHONAMIDE 5-AMINO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE-2,4-DISULFONAMIDE 5-Amino-alpha,alpha,alpha-trifluorotoluene-2,4-disulphonamide Trifluoromethyldisulfonamide 2,4-Disulfamyl-5-trifluoromethylaniline 4-Amino-6-(Trifluoromethyl)Benzene-1,3-Disulphonamide 3-(4-methylphenyl)sulfonylpropane-1,2-diol Bendroflumethiazide EP Impurity A Bendroflumethiazide impurity A CRS 4-Amino-6-(trifluoromethyl)benzene- 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (TFMSAA) Bendroflumethiazide EP Impurity 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide ISO 9001：2015 REACH 4-Amino-6-(trifluoromethyl)benzene-1,3-d 4Amino6(trifluoromethyl)benzene1,3disulfonamide,4 Amino 6 (trifluoromethyl)benzene 1,3 disulfonamide 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide（TFDSA）（Intermediate of Bendroflumethiazide） NSC 44625 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide, 10 mM in DMSO 654-62-6 C7H8F3N3O4S2 Building Blocks Organic Building Blocks Sulfonamides/Sulfinamides Sulfur Compounds A-AM Bioactive Small Molecules Building Blocks Cell Biology Chemical Synthesis Organic Building Blocks Sulfonamides/Sulfinamides Sulfur Compounds