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beta-Cyclodextrin methyl ethers

CAS No.
128446-36-6
Chemical Name:
beta-Cyclodextrin methyl ethers
Synonyms
Methyl-β-cyclodextrin;MBC;METHYL-BETA-CYCLODEXTRIN;Me-β-CD;Methyl-beta-cyclodextrine;MBCD;MEBCD;Me-β-CD;BETA-CYD;RM-β-CD-o
CBNumber:
CB5696215
Molecular Formula:
C54H94O35
Molecular Weight:
1303.3
MDL Number:
MFCD00074980
MOL File:
128446-36-6.mol
Last updated:2023-09-18 15:08:07

beta-Cyclodextrin methyl ethers Properties

Melting point 180-182 °C(lit.)
alpha +159°(25℃, c=1, H2O)
Flash point 187 °C
storage temp. room temp
solubility H2O: soluble50mg/mL
form powder
color White to off-white
optical activity [α]25/D +159°, c = 1 in H2O
Water Solubility Soluble in water
InChIKey YZOUYRAONFXZSI-SBHWVFSVSA-N
LogP -2.566 (est)
FDA UNII F9TVU546K5
EPA Substance Registry System .beta.-Cyclodextrin, methyl ethers (128446-36-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H317-H361
Precautionary statements  P201-P202-P261-P272-P280g-P302+P352-P308+P313-P363-P403-P501c
Safety Statements  22-24/25
WGK Germany  3
TSCA  Yes
HS Code  35051000
NFPA 704
1
0 0

beta-Cyclodextrin methyl ethers price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 332615 Methyl-β-cyclodextrin average Mn 1310 128446-36-6 5g $52.5 2024-03-01 Buy
Sigma-Aldrich 332615 Methyl-β-cyclodextrin average Mn 1310 128446-36-6 25g $171 2024-03-01 Buy
TCI Chemical M1356 Methyl-β-cyclodextrin (mixture of several Methylated) 128446-36-6 25g $109 2024-03-01 Buy
TCI Chemical M1356 Methyl-β-cyclodextrin (mixture of several Methylated) 128446-36-6 250g $544 2024-03-01 Buy
Alfa Aesar J66847 Methyl-beta-cyclodextrin 128446-36-6 5g $47.5 2024-03-01 Buy
Product number Packaging Price Buy
332615 5g $52.5 Buy
332615 25g $171 Buy
M1356 25g $109 Buy
M1356 250g $544 Buy
J66847 5g $47.5 Buy

beta-Cyclodextrin methyl ethers Chemical Properties,Uses,Production

Description

Methyl-β-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-cyclodextrin . Methyl-β-cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes. Methyl-β-cyclodextrin (5 mM) reduces α-synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein. It also reduces α-synuclein levels in mouse brain in a transgenic model of α-synucleinopathy.

Chemical Properties

White powder

Uses

Methyl-β-cyclodextrin is a cholesterol-removing agent mainly used for lipid raft disruption. It may also be used for detergent removal from protein-lipid-detergent ternary mixture to produce 2D membrane protein crystals due to its high solubility and affinity for detergents generally used in membrane protein chemistry.

Uses

Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

Uses

substrate for laminarinase and other glucanases

General Description

Methyl-β-cyclodextrin is a small cyclic heptasaccharide.

Biochem/physiol Actions

Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells.

beta-Cyclodextrin methyl ethers Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 342)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86-13288715578 +86-13231137666 sales@hbmojin.com China 12409 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5960 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9359 55
Anhui Royal Chemical Co., Ltd.
+86-25-86655873 +8613962173137 marketing@royal-chem.com China 535 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Henan Xiangtong Chemical Co., Ltd.
86-371-61312303 info@hnxtchem.com CHINA 292 58

View Lastest Price from beta-Cyclodextrin methyl ethers manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL CYCLODEXTRIN pictures 2023-11-30 METHYL CYCLODEXTRIN
128446-36-6
US $0.00 / kg 100kg 99% 20Tons ZhenYiBio Technology Inc
beta-Cyclodextrin methyl ethers pictures 2023-09-18 beta-Cyclodextrin methyl ethers
128446-36-6
US $40.00-40.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
beta-Cyclodextrin methyl ethers pictures 2023-06-28 beta-Cyclodextrin methyl ethers
128446-36-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
.beta.-cyclodextrin,methylethers BETA-W7 M1.8 BETA-CYD (Mixture of several Methylated) Methyl-beta-cyclodextrin  Methyl-beta-cyclodextrin (mixture of several Methylated) Methyl-β-cyclodextrin [average M.W. 1310] Methyl-β-cyclodextrin (Mixture of several Methylated) Methylated-B-cyclodextrin Cavasol? W7 M Cavasol? W7 M PH Methylated-β-Cyclodextrin Methyl-beta-cyclodextrin Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, >=98.0% cyclodextrin basis MEBCD Methyl-beta-cyclodextrin(Me-β-CD) Methylophioponanone B β-Cyclodextrin methyl ethers Methyl-β-cyclodextrin, Average Mn approx. 1310 RM-β-CD-o Randomly methylated-β-Cyclodextrin Dimethyl-β-Cyclodextrin Methyl-?cyclodextrin methyl-B-cyclodextrin cell culture*tested methyl-β-cyclodextrin cyclomaltoheptaose, methylether (RANDOM) METHYL BETA CYCLODEXTRIN,*TECHNICAL GRADE METHYL-B-CYLODEXTRIN NON-TOXIC SOLUBILIZ ER (RANDOM) METHYL BETA-CYCLODEXTRIN,*PHARMACEUTICAL G Methyl-Beta-cyclodextrin=Cyclodextrinmethyle METHYL-SS-CYCLODEXTRIN B-Cyclodextrin methyl ether METHYL B-CYCLODEXTRIN Methyl-beta-cyclodextrin,average Mn ~1310 pharmaceutical grade beta-Cyclodextrin methyl ethers pharmaceutical grade MEBCD pharmaceutical grade Methylated-beta-Cyclodextrin pharmaceutical grade Methylated-β-Cyclodextrin pharmaceutical grade methyl-B-cyclodextrin pharmaceutical grade Methyl-beta-cyclodextrin (mixture of several Methylated) pharmaceutical grade Methyl--cyclodextrin pharmaceutical grade methyl-β-cyclodextrin pharmaceutical grade Me-β-CD pharmaceutical grade methyl-beta-cyclodextrin Methyl-b-cyclodextrin - 3 to 9 degree of substitution Heptapkis ( 2,6-di-o-Methyl)-β-cyclodextrin METHYL-BETA-CYCLODEXTRIN;MΒCD Methyl-beta-cyclodextrin (DS~12) Methyl-beta-cyclodextrin (Mixture of Methylated) hot selling beta-Cyclodextrin methyl ethers top quality beta-Cyclodextrin methyl ethers beta-Cyclodextrin methyl ethers USP/EP/BP Methyl-β-cyclodextrin (Mixture of Methylated) beta-Cyclodextrin methyl ethers cyclodextrin Randomly methylated-β-Cyclodextrin Methyl--cyclodextrin, 98%+ β-Cyclodextrin, methyl ethers Methyl-β-cyclodextrin (mixture of several Methylated) Methylated-β-Cyclodextrin METHYL-BETA-CYCLODEXTRIN