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3,4-Dichloroaniline

CAS No.
95-76-1
Chemical Name:
3,4-Dichloroaniline
Synonyms
3,4-dca;Gefitinib-1;3.4-Dichloroan;3,4-Dichloroanil;3,4-Dichloranilin;AKOS BBS-00003672;3,4-Dichloraniline;3,4-Dichloroanihne;3,4-DICHLOROANILINE;3,4-dichloro-anilin
CBNumber:
CB5696598
Molecular Formula:
C6H5Cl2N
Molecular Weight:
162.02
MDL Number:
MFCD00007768
MOL File:
95-76-1.mol
MSDS File:
SDS
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
3,4-Dichloroaniline 98% 437778 5g $37.5
3,4-Dichloroaniline certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland CRM35827 1 unit $81.9
3,4-Dichloroaniline 98% 437778 250g $98.2
3,4-Dichloroaniline certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland CRM35827 50MG $81.9
3,4-Dichloroaniline >98.0%(GC) D0324 25g $30
More product size

3,4-Dichloroaniline Properties

Melting point 69-71 °C(lit.)
Boiling point 272 °C(lit.)
Density 1,34 g/cm3
vapor pressure 97.5Pa at 78℃
refractive index 1.6140 (estimate)
Flash point 166 °C
storage temp. 0-6°C
solubility 0.73g/l
pka 2.90±0.10(Predicted)
form Crystalline Mass and/or Chunks
color Beige to brown
PH 7.1 (0.8g/l, H2O)
Water Solubility 0.06 g/100 mL
Merck 14,3054
BRN 636837
Stability Stable, but darkens in storage. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
LogP 2.68 at 20℃
CAS DataBase Reference 95-76-1(CAS DataBase Reference)
EWG's Food Scores 3-4
FDA UNII 20KR9WJ4NS
NIST Chemistry Reference Benzenamine, 3,4-dichloro-(95-76-1)
EPA Substance Registry System 3,4-Dichloroaniline (95-76-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H301+H311+H331-H317-H318-H410
Precautionary statements  P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338
Hazard Codes  T,N
Risk Statements  23/24/25-41-43-50/53-51/53-33
Safety Statements  26-36/37/39-45-60-61-36/37-28
RIDADR  UN 3442 6.1/PG 2
WGK Germany  3
RTECS  BX2625000
8
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29214210
Hazardous Substances Data 95-76-1(Hazardous Substances Data)
Limited Quantities 100ml (liquid) or 0.5 Kg (solid)
Excepted Quantities Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

3,4-Dichloroaniline price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 437778 3,4-Dichloroaniline 98% 95-76-1 5g $37.5 2025-07-31 Buy
Sigma-Aldrich CRM35827 3,4-Dichloroaniline certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland 95-76-1 1 unit $81.9 2025-07-31 Buy
Sigma-Aldrich 437778 3,4-Dichloroaniline 98% 95-76-1 250g $98.2 2025-07-31 Buy
Sigma-Aldrich CRM35827 3,4-Dichloroaniline certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland 95-76-1 50MG $81.9 2024-03-01 Buy
TCI Chemical D0324 3,4-Dichloroaniline >98.0%(GC) 95-76-1 25g $30 2025-07-31 Buy
Product number Packaging Price Buy
437778 5g $37.5 Buy
CRM35827 1 unit $81.9 Buy
437778 250g $98.2 Buy
CRM35827 50MG $81.9 Buy
D0324 25g $30 Buy

3,4-Dichloroaniline Chemical Properties,Uses,Production

Description

3,4-Dichloroaniline, 1-amino3,4- dichlorobenzene, is a gray to dark-brown crystalline solid at room temperature. It is used as an intermediate for pesticides and dyes and is produced by catalytic hydrogenation of 3,4-dichloronitrobenzene with noble metal catalysts under pressure. Various types of additives prevent dehalogenation during production and reactors must be fabricated with special steel alloys to inhibit corrosion.

Description

3,4-Dichloroaniline, 1-amino- 3,4- dichlorobenzene, is a gray to dark-brown crystalline solid at room temperature. It is used as an intermediate for pesticides and dyes and is produced by catalytic hydrogenation of 3,4-dichloronitrobenzene with noble metal catalysts under pressure. Various types of additives prevent dehalogenation during production and reactors must be fabricated with special steel alloys to inhibit corrosion .

Chemical Properties

brown solid
3,4-Dichloroaniline

Uses

3,4-Dichloroaniline is used as an intermediate for pesticides and dyes.

Uses

3,4-Dichloroaniline is used in the preparation of the herbicide propanil (P760840).

Uses

3,4-Dichloroaniline may be employed as derivatization reagent for the HPLC analysis of perfluorooctanoic acid (PFOA).

Definition

ChEBI: A dichloroaniline having the two chloro-substituents at the 3- and 4-positions.

Preparation

3,4-Dichloroaniline is produced by catalytic hydrogenation of 3,4-dichloronitrobenzene with noble metal catalysts under pressure. Various types of additives prevent dehalogenation during production and reactors must be fabricated with special steel alloys to inhibit corrosion.

General Description

Light tan to dark gray crystals or brown solid. Melting point 71-72°C.

Air & Water Reactions

Sensitive to prolonged exposure to heat, light and air. Darkens in storage. Insoluble in water.

Reactivity Profile

3,4-Dichloroaniline is incompatible with oxidizing agetns, acids, acid chlorides and acid anhydrides. 3,4-Dichloroaniline can decompose at low pH. Hydrochloric acid accelerates decomposition. Reacts at temperatures above 356°F in the presence of ferric chloride .

Fire Hazard

3,4-Dichloroaniline is combustible.

Metabolic pathway

The basidiomycete Filoboletus sp. TA9054 metabolizes 3,4-dichloroaniline and forms several condensation products on solid media and in liquid culture, and no oligomers are produced. Six metabolites are identified as 3,3'-4,4'- tetrachloroazobenzene, 4-(3,4-dichloroanilino)-3,3',4' - trichloroazobenzene, 4-[(3,4-dichloroanilino)-4-(3,4- dichloroanilino)]-3,3'4'-trichloroazobenzene, 2-(3,4- dichloroanilino)-N-(3,4-dichlorophenyl)-4- (chlorophenylene), 6-(3,4-dichloroanilino)-N-(3,4- dichlorophenyl)-4-(chlorophenylene), and 3,5-bis(3,4- dichloroanilino)-1,4-chlorobenzoquinone.

Purification Methods

Crystallise the aniline from MeOH. [Beilstein 12 IV 1257.]

99-54-7
106-47-8
95-76-1
Synthesis of 3,4-Dichloroaniline from 3,4-Dichloronitrobenzene
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View Lastest Price from 3,4-Dichloroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-Dichloroaniline pictures 2025-11-10 3,4-Dichloroaniline
95-76-1
US $0.00 / kg 20kg 99% 20 tons Qingdao RENAS Polymer Material Co., Ltd.
3,4-Dichloroaniline pictures 2025-11-10 3,4-Dichloroaniline
95-76-1
US $10.00 / KG 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
3,4-Dichloroaniline pictures 2025-08-08 3,4-Dichloroaniline
95-76-1
US $0.00 / KG 1KG 99% 50000KG/month Sichuan Zhuoyu Yantang Technology Co., Ltd.
3,4-DICHLOROPHENYLAMINE 3,4-dichlorobenzenamine 3,4-Dichloroanihne 3,4-DICHLOROANILINE 3,4-Dichloranilin 3,4-Dichloraniline 3,4-Dichloroanaline 3,4-dichloro-anilin 3,4-dichloro-benzenamin 4,5-Dichloroaniline Aniline, 3,4-dichloro- LABOTEST-BB LTBB000652 1-AMINO-3,4-DICHLORO-BENZENE AKOS BBS-00003672 Benzenamine, 3,4-dichloro- 3,4-DICHLOROANILINE PESTANAL 3,4-Dichloroaniline,>98% 3,4-DichloroAniline(3,4-Dca)99.5% 3,4-dichloroaminobenzene) 3,4-DICHLOROBENZAMINE DICHLORO-3,4-ANILINE 3,4-Dichlorobenzeneamine 3,4-Dichloroaniline, 98% 250GR 3,4-Dichloroaniline, 98% 5GR 3, 4-2 chloro aniline 3.4-Dichloroan Gefitinib IMpurity III Gefitinib-1 3,4-Dichloroanil high quality 3,4-Dichloroanilinekf-wang(at)kf-chem.com m,p-dichloroaniline 3,4-DichloroanilineSolution,1,000mg/L,1ml 3,4-Dichloroaniline > 3,4-DichloroanilineSolution,100mg/L,1ml 3,4-Dichloroaniline ISO 9001:2015 REACH 3-OXO-3-P-TOLYL-PROPIONI 3,4-dca 3,4-Dichloroaniline,99% Gefitinib Impurity 25 Gefitinib Impurity 3 3,4-Dichloroaniline in methanol Dichloroaniline (15 mg) (3,4-Dichloroaniline) 3,4-Dichloroaniline Solution in Toluene 3,4-Dichloroaniline 100 μg/ml Methanol 3,4-Dichloroaniline 100 μg/ml Toluene C12323400 3,4-Dichloroaniline XA12323400AL3,4-DichloroanilinE100μg/mLin Ac 3,4-Dichloroaniline 100 μg/mL in Acetonitrile 95-76-1 122-51-4 Building Blocks Amines C2 to C6 Nitrogen Compounds Organic Building Blocks amine | alkyl chloride Aromatics Miscellaneous Reagents