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THIOPHENE-2-THIOCARBOXAMIDE

THIOPHENE-2-THIOCARBOXAMIDE structure

CAS No.: 20300-02-1

Chemical Name:: THIOPHENE-2-THIOCARBOXAMIDE

Synonyms: THIOPHENE-2-CARBOTHIOAMIDE;THIOPHENE-2-THIOAMIDE;OTAVA-BB BB7020331311;2-Thiocarbamoylthiophene;2-Thienylthiocarboxamide;2-Thiophenecarbothioamide;Thiophen-2-carbothioamide;Thiophen-2-thiocarboxamid;2-Thiophenethiocarboxamide;THIOPHENE-2-THIOCARBOXAMIDE

CBNumber:: CB5697863

Molecular Formula:: C5H5NS2

Molecular Weight:: 143.23

MDL Number:: MFCD00052890

MOL File:: 20300-02-1.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
Thiophene-2-carbothioamide Aldrich^CPR	CDS014286	250 mg	$73.1
Thiophene-2-carbothioamide >98.0%(HPLC)	T3604	5g	$407
Thiophene-2-carbothioamide >98.0%(HPLC)	T3604	25g	$1286
Thiophene-2-thiocarboxamide	T430110	10mg	$45
Thiophene-2-thiocarboxamide	T430110	50mg	$60
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THIOPHENE-2-THIOCARBOXAMIDE Properties

Melting point	106 °C
Boiling point	260℃
Density	1.357
Flash point	111℃
storage temp.	2-8°C(protect from light)
form	powder to crystal
pka	12.56±0.29(Predicted)
color	White to Yellow to Green
Water Solubility	Insoluble in water.
BRN	110159
CAS DataBase Reference	20300-02-1(CAS DataBase Reference)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Warning

Hazard statements

H301-H315-H319-H335

Precautionary statements

P280h-P305+P351+P338-P309-P310

Hazard Codes

Risk Statements

25-43

Safety Statements

22-36/37/39-45-36/37

RIDADR

2811

Hazard Note

Irritant

HazardClass

6.1

PackingGroup

III

HS Code

2934999090

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
3		0

THIOPHENE-2-THIOCARBOXAMIDE price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS014286	Thiophene-2-carbothioamide Aldrich^CPR	20300-02-1	250 mg	$73.1	2025-07-31	Buy
TCI Chemical	T3604	Thiophene-2-carbothioamide >98.0%(HPLC)	20300-02-1	5g	$407	2025-07-31	Buy
TCI Chemical	T3604	Thiophene-2-carbothioamide >98.0%(HPLC)	20300-02-1	25g	$1286	2025-07-31	Buy
TRC	T430110	Thiophene-2-thiocarboxamide	20300-02-1	10mg	$45	2021-12-16	Buy
TRC	T430110	Thiophene-2-thiocarboxamide	20300-02-1	50mg	$60	2021-12-16	Buy

Product number	Packaging	Price	Buy
CDS014286	250 mg	$73.1	Buy
T3604	5g	$407	Buy
T3604	25g	$1286	Buy
T430110	10mg	$45	Buy
T430110	50mg	$60	Buy

THIOPHENE-2-THIOCARBOXAMIDE Chemical Properties,Uses,Production

Uses

Thiophene-2-thiocarboxamide is used as a pharmaceutical intermediate.

Synthesis

5813-89-8

20300-02-1

General procedure for the synthesis of thiophene-2-thioformamide from 2-thiophenecarboxamide: 2-thiophenecarboxamide (1 g, 7.86 mmol) was dissolved in dry 1,2-dimethoxyethane (30 mL). Lawesson's reagent (1.6 g, 3.9 mmol) was added and the reaction was protected under nitrogen. The reaction mixture was stirred at room temperature for 12 hours and then filtered. Subsequently, the solvent was removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 10:1 to 2:1) to afford thiophene-2-thiocarboxamide (1.0 g, 88.8% yield, white solid). Thiophene-2-carbothioamide can be used directly in the subsequent reaction without further purification.

References

[1] Patent: EP2708534, 2014, A1. Location in patent: Paragraph 0055
[2] ACS Medicinal Chemistry Letters, 2013, vol. 4, # 10, p. 904 - 908
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 17, p. 7512 - 7523
[4] Chemistry - A European Journal, 2013, vol. 19, # 29, p. 9655 - 9662
[5] Journal of Chemical Research, 2010, # 3, p. 151 - 153

THIOPHENE-2-THIOCARBOXAMIDE Preparation Products And Raw materials

Raw materials

N-Methyl-2-pyrrolidone 2-Thiophenecarboxaldehyde N,N-Dimethylformamide Hydroxylamine hydrochloride Sodium hydrosulfide

Magnesium chloride hexahydrate 2-THIOPHENECARBOXAMIDE 2-Thiophenecarbonitrile Lawesson's Reagent 1,2-Dimethoxyethane

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Preparation Products

THIOPHENE-2-THIOCARBOXAMIDE Suppliers

Global( 139)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13493	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29847	58
Changzhou Carman Chemical Co., Ltd.	15061933924		CHINA	514	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3588	58
Shanghai Rlavie Technology Co ltd	+86-021-67759270 +8617717059219	sales@rlavie.com	China	1030	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10237	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Carman Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanghai Rlavie Technology Co ltd	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from THIOPHENE-2-THIOCARBOXAMIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	THIOPHENE-2-THIOCARBOXAMIDE 20300-02-1	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.
2022-01-04	Thiophene-2-thiocarboxamide 20300-02-1	US $0.00 / KG	1g	98%minHPLC	50kgs/month	Shanghai Rlavie Technology Co ltd
2020-04-23	Thiophene-2-carbothioic acid amide 20300-02-1	US $0.01-1.00 / KG	1KG	99%	20 tons	Shaanxi Dideu Medichem Co. Ltd

THIOPHENE-2-THIOCARBOXAMIDE
20300-02-1
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

Thiophene-2-thiocarboxamide
20300-02-1
US $0.00 / KG
98%minHPLC
Shanghai Rlavie Technology Co ltd

Thiophene-2-carbothioic acid amide
20300-02-1
US $0.01-1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

THIOPHENE-2-THIOCARBOXAMIDE Spectrum

THIOPHENE-2-THIOCARBOXAMIDE(20300-02-1)¹HNMR

20300-02-1(THIOPHENE-2-THIOCARBOXAMIDE)Related Search:

THIOPHENE-3-THIOCARBOXAMIDE THIFLUZAMIDE 3-Thiopheneboronic acid 3-THIOPHENECARBOXYLIC ACID HYDRAZIDE 5,5-Dimethyl-2-(thiophen-2-yl)-1,3,2-dioxaborinane

Thiophene-2,3-dicarboxylicacid Dimethyl thiophene-2,3-dicarboxylate Thiazolyl Blue Pseudothiohydantoin 2,5-Bis-Thiopheneboronic acid pinacol ester

Thiophene-2,3-dicarboxylic acid THIENO[3,2-B]PYRIDINE Ethylthiophene-2-carboximidoatehydrochloride ETHYL THIOPHENE-2-GLYOXYLATE 2(5 H)-THIOPHENONE

2-Thiophenesulfonic acid (2-methylphenyl)(thien-2-yl)methanone 3-AMinothiophene Oxalate

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OTAVA-BB BB7020331311 THIOPHENE-2-THIOAMIDE THIOPHENE-2-THIOCARBOXAMIDE THIOPHENE-2-CARBOTHIOIC ACID AMIDE Thiophene-2-carbothioamide, 95+% Thiophene-2-carbothioic acid amide, 2-Carbamothioylthiophene 2-(Aminothiocarbonyl)thiophene 2-Thienylthiocarboxamide 2-Thiocarbamoylthiophene 2-Thiophenecarbothioamide 2-Thiophenethiocarboxamide Thiophen-2-carbothioamide thiohypofluorous acid (4-oxo-3,4-dihydro-2H-1-benzopyran-6-yl) ester Thiophen-2-thiocarboxamid Thiophene-2-thiocarboxamide-97% THIOPHENE-2-CARBOTHIOAMIDE 20300-02-1