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Isopropyl chloroformate

CAS No.
108-23-6
Chemical Name:
Isopropyl chloroformate
Synonyms
isopropyl carbonochloridate;IPCF;ISOPROPYL CHLOROCARBONATE;ISOPROPYL CHLOROMATE;Isopropyl chloroform;1-PROPYLCHLOROFORMATE;2-Methylchloroformate;Tenofovir Impurity 95;Isopropylchlorcarbonat;ISOPROPYL CHLOROFORMATE
CBNumber:
CB5702693
Molecular Formula:
C4H7ClO2
Molecular Weight:
122.55
MDL Number:
MFCD00075068
MOL File:
108-23-6.mol
Last updated:2023-05-15 10:43:54

Isopropyl chloroformate Properties

Boiling point 105 °C
Density 0.892 g/mL at 25 °C
vapor pressure 27.998hPa at 20℃
refractive index n20/D 1.485(lit.)
Flash point 43 °F
storage temp. 2-8°C
solubility Chloroform (Sparingly), Dichloromethane (Soluble), Ethyl Acetate (Slightly), Tol
BRN 506416
Stability Moisture Sensitive
InChIKey IVRIRQXJSNCSPQ-UHFFFAOYSA-N
CAS DataBase Reference 108-23-6(CAS DataBase Reference)
FDA UNII 8LG1G18VXR
EPA Substance Registry System Isopropyl chloroformate (108-23-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H304-H314-H317-H330-H336-H361d-H373
Precautionary statements  P210-P260-P280-P284-P301+P310-P305+P351+P338
Hazard Codes  F,C,T+
Risk Statements  11-34-48/20-63-65-67-43-26
Safety Statements  26-36/37/39-45-62-28-16
RIDADR  UN 3286 3/PG 2
WGK Germany  2
RTECS  LQ6475000
10-19
HazardClass  6.1(a)
PackingGroup  I
HS Code  29159000

Isopropyl chloroformate price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 335908 Isopropyl chloroformate solution 1.0M in toluene 108-23-6 100ml $101 2024-03-01 Buy
Sigma-Aldrich 335908 Isopropyl chloroformate solution 1.0M in toluene 108-23-6 800ml $201 2024-03-01 Buy
TRC I824330 IsopropylChloroformate,30%inToluene 108-23-6 10g $80 2021-12-16 Buy
TRC I824330 IsopropylChloroformate,30%inToluene 108-23-6 100g $225 2021-12-16 Buy
Matrix Scientific 139325 Isopropyl chloroformate 95%+ 108-23-6 5g $323 2021-12-16 Buy
Product number Packaging Price Buy
335908 100ml $101 Buy
335908 800ml $201 Buy
I824330 10g $80 Buy
I824330 100g $225 Buy
139325 5g $323 Buy

Isopropyl chloroformate Chemical Properties,Uses,Production

Chemical Properties

Isopropyl chloroformate is a colorless liquid with corrosive properties and a pungent odor. generally present as 1.0 mol/L toluene solution of isopropyl chloroformate. It is a highly flammable chemical. Isopropyl chloroformate decomposes when heated, producing toxic and corrosive fumes, including hydrogen chloride and phosgene. The chemical reacts with water to produce alcohol and hydrogen chloride. Hydrolysis would yield chloroformic acid, which is considered a strong acid.

Uses

Chemical intermediate for free-radical polymerization initiators, organic synthesis.

Uses

Isopropyl chloroform was used in the preparation of isopropyl cyclohexane via alkylation of cyclohexene. It was also used in the preparation of 10-isopropyloctadecanoic acid via reaction with oleic acid in the presence of ethylaluminum sesquichloride

Production Methods

Prepared by the reaction of liquid anhydrous isopropyl alcohol with molar excess of dry, chlorine-free phosgene at low temperature.

General Description

A clear colorless volatile liquid with a pungent irritating odor. About the same density as water and insoluble in water. Floats on water Flash point 75°F. Very irritating to skin and eyes and very toxic by inhalation, ingestion and skin absorption. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Gives off HCl fumes in moist air. Insoluble in water. Decomposes slowly in water forming isopropyl alcohol, HCl, and CO2.

Reactivity Profile

Isopropyl chloroformate is water reactive. A sample stored in a refrigerator exploded [Wischmeyer 1973]. Attacks many metals especially in humid atmosphere [Handling Chemicals Safely, 1980. p. 476]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Toxic by inhalation.

Health Hazard

Acute: highly toxic by inhalation, ingestion and skin absorption. Delayed: can produce delayed pulmonary edema (2-24 hours after exposure) similar to that produced by phosgene. Inhalation of material may cause death or permanent injury.

Fire Hazard

Extremely dangerous; Isopropyl chloroformate has exploded while stored in refrigerator. Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Like other chlorides, when heated to decomposition or on contact with acids or acrid fumes, they evolve highly toxic chloride fumes. Reacts violently with phosgene. Unstable, avoid phosgene

Global( 319)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
ATK CHEMICAL COMPANY LIMITED
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View Lastest Price from Isopropyl chloroformate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isopropyl Chlorocarbonate pictures 2023-03-31 Isopropyl Chlorocarbonate
108-23-6
US $50.00 / kg 1kg 99% 20 tons Hebei Duling International Trade Co. LTD
Isopropyl chloroformate pictures 2023-03-23 Isopropyl chloroformate
108-23-6
US $10.00 / KG 1KG 99% 10 ton Hebei Guanlang Biotechnology Co,.LTD
Isopropyl chloroformate pictures 2019-07-06 Isopropyl chloroformate
108-23-6
US $1.00 / kg 1kg 99% Customized Career Henan Chemical Co
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