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tert-Butyl diethylphosphonoacetate

tert-Butyl diethylphosphonoacetate structure

CAS No.: 27784-76-5

Chemical Name:: tert-Butyl diethylphosphonoacetate

Synonyms: tert-butyl 2-(diethoxyphosphoryl)acetate;tert-Butyl diethylph;DIETHYL (BOC-METHYL)PHOSPHONATE;T-BUTYL DIETHYL PHOSPHONOACETATE;Tert-buty diethylphosphonoacetate;tert-Butyl diethylphosponoacetate;Tert-butyl diethylphosphonoactate;TERT-BUTYL DIETHYLPHOSPHONOACETATE;Tert-butyl diehylphosphonoacetate;Tert-butyl diethyl phosphonylacetate

CBNumber:: CB5708211

Molecular Formula:: C10H21O5P

Molecular Weight:: 252.24

MDL Number:: MFCD00075414

MOL File:: 27784-76-5.mol

MSDS File:: SDS

Last updated:2024-01-23 13:05:57

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tert-Butyl diethylphosphonoacetate Properties

Boiling point	100-103 °C/1.5 mmHg (lit.)
Density	1.074 g/mL at 25 °C (lit.)
refractive index	n20/D 1.431(lit.)
Flash point	>230 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Liquid
Specific Gravity	1.074
color	Clear colorless
Water Solubility	Not miscible or difficult to mix in water.
BRN	2050126
InChI	InChI=1S/C10H21O5P/c1-6-13-16(12,14-7-2)8-9(11)15-10(3,4)5/h6-8H2,1-5H3
InChIKey	NFEGNISFSSLEGU-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(=O)CP(OCC)(OCC)=O
CAS DataBase Reference	27784-76-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P305+P351+P338-P321-P332+P313-P337+P313

Risk Statements

36/38

Safety Statements

26-36-24/25

WGK Germany

HS Code

29319090

NFPA 704

	1
2		1

tert-Butyl diethylphosphonoacetate price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	348333	tert-Butyl diethylphosphonoacetate 95%	27784-76-5	5g	$114	2023-01-07	Buy
TCI Chemical	B2814	tert-Butyl Diethylphosphonoacetate >97.0%(GC)	27784-76-5	1g	$28	2024-03-01	Buy
TCI Chemical	B2814	tert-Butyl Diethylphosphonoacetate >97.0%(GC)	27784-76-5	5g	$80	2024-03-01	Buy
Alfa Aesar	L17651	tert-Butyl diethylphosphonoacetate, 95%	27784-76-5	5g	$90.65	2024-03-01	Buy
Alfa Aesar	L17651	tert-Butyl diethylphosphonoacetate, 95%	27784-76-5	1g	$29.7	2021-12-16	Buy

Product number	Packaging	Price	Buy
348333	5g	$114	Buy
B2814	1g	$28	Buy
B2814	5g	$80	Buy
L17651	5g	$90.65	Buy
L17651	1g	$29.7	Buy

tert-Butyl diethylphosphonoacetate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless liquid

Uses

tert-Butyl diethylphosphonoacetate is used as a reactant for preparation of hydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents, synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3) and bicyclic triaminophosphine-promoted stereoselective synthesis of a,?-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates

Synthesis

Triethyl phosphite (485 g) is warmed up to 90°C under N2 atmosphere in a three-necked round-bottomed flask, and /-butyl bromoacetate (541 g) is added dropwise into the system within 2 h. Then, the mixture is stirred at 90°C for around 4 hours and cooled to room temperature. The obtained mixture is distilled under vacuo to remove compounds with low boiling points, and the residue is collected as a colorless liquid tert-butyl diethylphosphonoacetate in 97 percent yield (680 g).

tert-Butyl diethylphosphonoacetate synthesis

Synthesis of tert-Butyl diethylphosphonoacetate from tert-Butyl bromoacetate and Triethyl phosphite

tert-Butyl diethylphosphonoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl diethylphosphonoacetate (E)-tert-butyl 3-(4-cyanophenyl)acrylate TERT-BUTYL (3S)-3-AMINO-5-METHYLHEXANOATE, 97

tert-Butyl diethylphosphonoacetate Suppliers

Global( 290)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangxi Sunway Chemical Co., Ltd.	+86-0794-5259909 +8615888611133	dave@jxswchem.com	China	22	58
Jiangxi Sunway Chemical Co., Ltd.	+86-0794-5259909 +8615888611133	dave@jxswchem.com	China	22	58
Hangzhou ICH Biofarm Co., Ltd	+undefined8613073685410	sales@ichemie.com	China	985	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58

Supplier	Advantage
Jiangxi Sunway Chemical Co., Ltd.	58
Jiangxi Sunway Chemical Co., Ltd.	58
Hangzhou ICH Biofarm Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58

View Lastest Price from tert-Butyl diethylphosphonoacetate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-11-01	tert-Butyl diethylphosphonoacetate 27784-76-5	US $0.00-0.00 / kg	0.10000000149011612kg	99.0%min	200kg	Hangzhou ICH Biofarm Co., Ltd
2023-09-06	tert-Butyl diethylphosphonoacetate 27784-76-5	US $0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.
2023-06-26	tert-Butyl 2-(diethoxyphosphoryl)acetate 27784-76-5	US $200.00 / kg	10kg	99%	500kg/month	Hebei Mingeng Biotechnology Co., Ltd

tert-Butyl diethylphosphonoacetate
27784-76-5
US $0.00-0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

tert-Butyl diethylphosphonoacetate
27784-76-5
US $0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

tert-Butyl 2-(diethoxyphosphoryl)acetate
27784-76-5
US $200.00 / kg
99%
Hebei Mingeng Biotechnology Co., Ltd

tert-Butyl diethylphosphonoacetate Spectrum

tert-Butyl diethylphosphonoacetate(27784-76-5)¹HNMR tert-Butyl diethylphosphonoacetate(27784-76-5)IR tert-Butyl diethylphosphonoacetate(27784-76-5)Raman

27784-76-5(tert-Butyl diethylphosphonoacetate)Related Search:

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Mefenpyr-diethyl tert-Butyl acetate tert-Butylisocyanate

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DIETHYL(2-TERT-BUTOXYCARBONYLMETHYL)PHOSPHONATE (DIETHOXYPHOSPHORYL)ACETIC ACID TERT-BUTYL ESTER DIETHYL (BOC-METHYL)PHOSPHONATE DIETHYLPHOSPHONOACETIC ACID TERT-BUTYL ESTER DIETHYL (TERT-BUTOXYCARBONYLMETHYL)PHOSPHONATE T-BUTYL DIETHYL PHOSPHONOACETATE TERT-BUTYL DIETHYLPHOSPHONOACETATE tert-Butyl diethylphosphonoacetate, 98 % Tert-Butyl p,p-diethylphosphonoacetate ACETIC ACID, 2-(DIETHOXYPHOSPHINYL)-, 1,1-DIMETHYLETHYL ESTER Tert-buty diethylphosphonoacetate tert-Butyl diethylphosphonoacetate,95% Tert-butyl diehylphosphonoacetate tert-Butyl diethylph (Diethoxyphosphinyl)acetic acid 1,1-dimethylethyl ester Diethyl tert-butoxycarbonylmethanephosphonate tert-Butyl (diethoxyphosphinyl)acetate tert-Butyl diethylphosphonoacetate Diethyl (Boc-methyl)phosphonate Diethyl (tert-Butoxycarbonylmethyl)phosphonate Diethylphosphonoacetic Acid tert-Butyl Ester 3-[(2-methylpropan-2-yl)oxy-oxomethyl]pentan-3-ylphosphonic acid Diethyl(2-tert-butoxycarbonylmethyl)phosphonate 98% tert-Butyl diethylphosponoacetate Tert-butyl diethylphosphonoactate tert-Butyl Diethylphosphonoacetate > Tert-butyl diethyl phosphonylacetate TERT-BUTYL DIETHYLPHOSPHONOACETATE (27784-76-5) tert-butyl 2-(diethoxyphosphoryl)acetate 1,1-Dimethylethyl 2-(diethoxyphosphinyl)acetate ert-butyl2-diethoxyphosphorylacetate Diethyl phosphonoyl acetate tert butyl ester 27784-76-5 C2H5O2POCH2CO2CCH33 Horner-Wadsworth-Emmons Reagents Olefination Synthetic Reagents C-C Bond Formation C-C Bond Formation Horner-Wadsworth-Emmons Reagents Olefination 27784-76-5