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3-CHLORO-4-METHOXYBENZALDEHYDE

CAS No.
4903-09-7
Chemical Name:
3-CHLORO-4-METHOXYBENZALDEHYDE
Synonyms
40903-09-7;AKOS B029259;TIMTEC-BB SBB003854;CHEMBRDG-BB 6945816;3-chloroanisaldehyde;3-CHLORO-P-ANISALDEHYDE;3-CHLORO-4-METHOXYBENZALDEHYDE;4-Methoxy-3-chlorobenzaldehyde;3-Chloro-p-anisaldehyde;3-CHLORO-P-ANISALDEHYDE, 98+% GC
CBNumber:
CB5728000
Molecular Formula:
C8H7ClO2
Molecular Weight:
170.59
MDL Number:
MFCD00016601
MOL File:
4903-09-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:50

3-CHLORO-4-METHOXYBENZALDEHYDE Properties

Melting point 56-60 °C (lit.)
Boiling point 128 °C(Press: 5 Torr)
Density 1.244±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Almost white
Sensitive Air Sensitive
CAS DataBase Reference 4903-09-7(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Safety Statements  22-24/25
WGK Germany  3
HS Code  29130000
NFPA 704
1
2 0

3-CHLORO-4-METHOXYBENZALDEHYDE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 565040 3-Chloro-4-methoxybenzaldehyde 97% 4903-09-7 1g $73.81 2025-07-31 Buy
Sigma-Aldrich 565040 3-Chloro-4-methoxybenzaldehyde 97% 4903-09-7 5g $178.6 2025-07-31 Buy
TCI Chemical C1797 3-Chloro-p-anisaldehyde >98.0%(GC) 4903-09-7 1g $50 2025-07-31 Buy
TCI Chemical C1797 3-Chloro-p-anisaldehyde >98.0%(GC) 4903-09-7 5g $143 2025-07-31 Buy
TRC C368965 3-Chloro-4-methoxybenzenecarbaldehyde 4903-09-7 10mg $60 2021-12-16 Buy
Product number Packaging Price Buy
565040 1g $73.81 Buy
565040 5g $178.6 Buy
C1797 1g $50 Buy
C1797 5g $143 Buy
C368965 10mg $60 Buy

3-CHLORO-4-METHOXYBENZALDEHYDE Chemical Properties,Uses,Production

Uses

3-Chloro-4-methoxybenzaldehyde is mainly used in organic synthesis, as a drug intermediate and chemical reagent, and is widely used in pharmaceuticals, materials science and other fields.

Synthesis

3-Chloro-4-hydroxybenzaldehyde

2420-16-8

Iodomethane

74-88-4

3-CHLORO-4-METHOXYBENZALDEHYDE

4903-09-7

Potassium carbonate (K2CO3, 7.6 g, 55.238 mmol) was added to a stirred solution of 3-chloro-4-hydroxybenzaldehyde (2.9 g, 18.412 mmol) in N,N-dimethylformamide (DMF, 30 mL). Iodomethane (CH3I, 7.80 g, 55.238 mmol) was added slowly and dropwise at room temperature under inert atmosphere. After the dropwise addition, the reaction mixture was heated to 80 °C and stirred continuously for 1 hour. Upon completion of the reaction, the reaction was quenched with deionized water (20 mL) and subsequently extracted with ethyl acetate (EtOAc, 2 x 50 mL). The organic phases were combined, washed sequentially with deionized water and saturated saline, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography to afford 3-chloro-4-methoxybenzaldehyde (2.78 g, 93% yield) as a yellow solid.

References

[1] Patent: US2003/176481, 2003, A1
[2] Patent: WO2009/158393, 2009, A1. Location in patent: Page/Page column 113-114
[3] Patent: US6313146, 2001, B1
[4] Patent: US6582351, 2003, B1

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View Lastest Price from 3-CHLORO-4-METHOXYBENZALDEHYDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Chloro-p-anisaldehyde pictures 2025-01-03 3-Chloro-p-anisaldehyde
4903-09-7
US $0.00-0.00 / g 10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
4-Methoxy-3-chlorobenzaldehyde AKOS B029259 TIMTEC-BB SBB003854 3-CHLORO-4-METHOXYBENZALDEHYDE 3-CHLORO-4-METHOXYBENZENECARBALDEHYDE 3-CHLORO-P-ANISALDEHYDE CHEMBRDG-BB 6945816 3-chloroanisaldehyde 3-CHLORO-P-ANISALDEHYDE, 98+% GC 3-chloro-4-methoxybenzaldehyde(SALTDATA: FREE) 3-Chloro-4-methoxybenzaldehyde 97% 3-Chloro-p-anisaldehyde 40903-09-7 2-[(2-prop-2-enylphenoxy)methyl]oxirane Benzaldehyde, 3-chloro-4-methoxy- 4'-Bromo-2,2,3-trifluoroacetophenone 4903-09-7 40903-09-7 4903-9-7 1097074 4903-07-9 CH3OC6H3ClCHO ALDEHYDE Organic Building Blocks C8 Carbonyl Compounds Aldehydes Building Blocks Benzaldehyde Adehydes, Acetals & Ketones Anisoles, Alkyloxy Compounds & Phenylacetates Chlorine Compounds Aromatic Aldehydes & Derivatives (substituted)