2-Bromobiphenyl
- CAS No.
- 2052-07-5
- Chemical Name:
- 2-Bromobiphenyl
- Synonyms
- 2-bromo-1,1'-biphenyl;pbb 1;PBB NO 1;2-Brombiphenyl;o-Bromobiphenyl;2-BROMODIPHENYL;2-BROMOBIPHENYL;2- Bromobenzene;BROMOBIPHENYL(2-);Biphenyl, 2-bromo-
- CBNumber:
- CB5733745
- Molecular Formula:
- C12H9Br
- Molecular Weight:
- 233.1
- MDL Number:
- MFCD00000065
- MOL File:
- 2052-07-5.mol
| Melting point | 1.5-2 °C(lit.) |
|---|---|
| Boiling point | 297-298 °C(lit.) |
| Density | 1.352 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 113 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly, Heated), Methanol (Slightly) |
| form | Liquid |
| Specific Gravity | 1.352 |
| color | Clear colorless |
| Water Solubility | Insoluble |
| BRN | 1863156 |
| Stability | Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 2052-07-5(CAS DataBase Reference) |
| FDA UNII | GXS4234YXD |
| NIST Chemistry Reference | 1,1'-Biphenyl, 2-bromo-(2052-07-5) |
| EPA Substance Registry System | 2-Bromobiphenyl (2052-07-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H317-H411-H372 | |||||||||
| Precautionary statements | P273-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 23-24/25-37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29036990 | |||||||||
| NFPA 704 |
|
2-Bromobiphenyl price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 252247 | 2-Bromobiphenyl 96% | 2052-07-5 | 5g | $134 | 2024-03-01 | Buy |
| Alfa Aesar | B21840 | 2-Bromobiphenyl, 98% | 2052-07-5 | 1g | $23.1 | 2023-06-20 | Buy |
| Alfa Aesar | B21840 | 2-Bromobiphenyl, 98% | 2052-07-5 | 5g | $73.1 | 2023-06-20 | Buy |
| Alfa Aesar | B21840 | 2-Bromobiphenyl, 98% | 2052-07-5 | 25g | $268 | 2023-06-20 | Buy |
| TRC | B680550 | 2-Bromo-1,1''-biphenyl | 2052-07-5 | 10g | $155 | 2021-12-16 | Buy |
2-Bromobiphenyl Chemical Properties,Uses,Production
Description
2-Bromobiphenyl is an important intermediate, which can be used to synthesize 2,2'-dibromo-9,9'-spirobifluorene, 3-bromo-9-(9-phenylfluoren-9-yl)carbazole and phenanthrene compounds.
Uses
2-Bromobiphenyl can be used as reference compound to investigate extraction efficiency of solid-phase microextraction fibers, based on methacrylic acid-trimethylolpropanetrimethacrylate copolymers.
synthesis
Carry out all catalytic reactions in reaction vessels open to the air. Charge a round-bottom flask with the newly purchased or freshly recrystallized aryl boronic acid (2.0 mmol), 1,2-dibromobenzene, powdered K3PO4 (2.2 mmol) and toluene (2.5 mL) of technical quality. Stir the mixture vigorously. Heat the mixture to 80 °C for 10 minutes. Add (0.2 mol%) of catalyst by syringe as a 2.5 ml of toluene solution to the mixture. Take the samples periodically from the reaction mixture. Quench the reaction with water. Extract the mixture with ethyl acetate. Analyze the reaction by GC-MS. At the end of catalytic reaction, cool the reaction mixture to room temperature. Quench the mixture with water (adjusted to an appropriate pH when biaryls with acidic or basic groups has to be extracted). Extract the mixture with ethyl acetate (3×40 mL). Dry the combined extracts (MgSO4). Evaporate the combined extracts to dryness. Purify the crude material by flash chromatography on silica gel.
Physical properties
2-Bromobiphenyl has a melting point of 1.5-2 °C, so it is a colorless liquid at room temperature. It boils at 297-298 °C. Its density at 25℃ is 1.352 g/mL. In general, 2-bromobiphenyls are stable, but they are not compatible with oxidants.
Uses
It is used as an intermediate of organic synthesis and pharmaceutical. It also can react with norborn-2-ene to get 5-phenyl-1,2,3,4,4a,8b-hexahydro-1,4-methanobiphenylene, in synthesis of a novel trispirocyclic hydrocarbon. It is used as a reference compound to investigate extraction efficiency of solid-phase micro extraction fibers, based on methacrylic acid-trimethylolpropanetrimethacrylate copolymers.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 3037, 1979 DOI: 10.1021/jo01331a016
Tetrahedron Letters, 21, p. 845, 1980 DOI: 10.1016/S0040-4039(00)71521-8
General Description
Clear liquid. Insoluble in water.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Bromobiphenyl is sensitive to light. Low reactivity.
Fire Hazard
Flash point data for 2-Bromobiphenyl are not available. 2-Bromobiphenyl is probably combustible.
2-Bromobiphenyl Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Free Trade Zone Violet Trade Co., Ltd. | +8618768051816; +8615858061377 | jenny@zjviolettech.com | China | 104 | 58 |
| Zhengzhou HQ Material CO.,LTD. | +86-371-55919009 +8615225108189 | sale1@hqmat.com | China | 633 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7433 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7933 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15933 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
Related articles
- Synthesis and Application of 2-Bromobiphenyl
- 2-Bromobiphenyl is an important pharmaceutical intermediate and organic intermediate.
- Aug 5，2022
View Lastest Price from 2-Bromobiphenyl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | 2-Bromobiphenyl
2052-07-5
|
US $0.00 / GK | 10g | 99.50% | 10TONS | Zhejiang Free Trade Zone Violet Trade Co., Ltd. | |
 |
2024-04-12 | 2-Bromobiphenyl
2052-07-5
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2024-01-02 | 2-Bromobiphenyl
2052-07-5
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 2-Bromobiphenyl
2052-07-5
- US $0.00 / GK
- 99.50%
- Zhejiang Free Trade Zone Violet Trade Co., Ltd.
-
- 2-Bromobiphenyl
2052-07-5
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- 2-Bromobiphenyl
2052-07-5
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd