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PTIO

CAS No.
18390-00-6
Chemical Name:
PTIO
Synonyms
PTIO;PTIO,98%;PTIO PTIO - CAS 18390-00-6;PTIO - CAS 18390-00-6 - Calbiochem;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE;PTIO (2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL);4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-2-PHENYL-1H-IMIDAZOL-1-YLOXY-1-OXIDE;[[4,4,5,5-Tetramethyl-2-phenyl-2-imidazoline 3-oxide]-1-yloxy]radical
CBNumber:
CB5747094
Molecular Formula:
C13H17N2O2*
Molecular Weight:
233.29
MDL Number:
MFCD00059929
MOL File:
18390-00-6.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:35

PTIO Properties

Melting point approximate 86℃
storage temp. 2-8°C
solubility soluble in Methanol
form Dark blue solid
color Blue to Dark blue

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2933.99.8210
NFPA 704
0
2 0

PTIO price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P5084 PTIO 18390-00-6 25mg $119.4 2024-03-01 Buy
Sigma-Aldrich 523350 PTIO Nitric oxide radical scavenger. 18390-00-6 25mg $182 2024-03-01 Buy
TCI Chemical A5440 PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere] >98.0%(T) 18390-00-6 1g $150 2024-03-01 Buy
TCI Chemical A5440 PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere] >98.0%(T) 18390-00-6 5g $450 2024-03-01 Buy
Cayman Chemical 14982 PTIO ≥98% 18390-00-6 25mg $37 2024-03-01 Buy
Product number Packaging Price Buy
P5084 25mg $119.4 Buy
523350 25mg $182 Buy
A5440 1g $150 Buy
A5440 5g $450 Buy
14982 25mg $37 Buy

PTIO Chemical Properties,Uses,Production

Description

PTIO is an oxidizing reagent that reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. It can be used to assay nitric oxide production when examining nitric oxide synthase inhibitory activity.

Chemical Properties

blue crystals

Uses

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.

Uses

PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO.

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 1078, 1968 DOI: 10.1021/ja01006a053

General Description

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.

Biochem/physiol Actions

Product does not compete with ATP.

PTIO Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[stablefreeradicalreagentforthesimultaneousdetermin 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL PTIO (2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL) PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere] [(2-Phenyl-4,4,5,5-tetramethyl-3-oxylato-4,5-dihydro-1H-imidazole-3-ium)-1-yloxy]radical [(4,5-Dihydro-2-phenyl-4,4,5,5-tetramethyl-1H-imidazole-3-oxide)-1-yloxy]radical [[(2-Phenyl-3-oxylato-4,4,5,5-tetramethyl-1H-imidazole-3-ium)-1-yl]oxy]radical [[2-Phenyl-4,4,5,5-tetramethyl-2-imidazoline 3-oxide]-1-yloxy]radical [[4,4,5,5-Tetramethyl-2-phenyl-2-imidazoline 3-oxide]-1-yloxy]radical PTIO,98% 4,5-Dihydro-4,4,5,5-tetramethyl-2-phenyl-1H-imidazol-1-yloxy-1-oxide 2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere] PTIO  PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere] 4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-2-PHENYL-1H-IMIDAZOL-1-YLOXY-1-OXIDE PTIO PTIO - CAS 18390-00-6 PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere]> PTIO(4,5-Dihydro-4,4,5,5-tetramethyl-2-phenyl-1H-imidazol-1-yloxy-1-oxide) PTIO - CAS 18390-00-6 - Calbiochem 18390-00-6 C13H17N2O2 Nitric Oxide Metabolism Enzymes, Inhibitors, and Substrates Nitric Oxide Scavengers BioChemical Biochemicals and Reagents Application Index Cell Signaling Enzymes