Dithizone
- CAS No.
- 60-10-6
- Chemical Name:
- Dithizone
- Synonyms
- DIPHENYLTHIOCARBAZONE;dithizon;Dithizone (min. 98%);1,5-diphenyl-3-thiocarbazone;(E)-1,5-diphenylthiocarbazone;Diazenecarbothioic acid, 2-phenyl-, 2-phenylhydrazide;Ditizon;DITHIZONE;usafek-3092;DITHIZONE(P)
- CBNumber:
- CB5753569
- Molecular Formula:
- C13H12N4S
- Molecular Weight:
- 256.33
- MDL Number:
- MFCD00003025
- MOL File:
- 60-10-6.mol
- MSDS File:
- SDS
| Melting point | 168 °C (dec.) (lit.) |
|---|---|
| Boiling point | 376.1±25.0 °C(Predicted) |
| Density | 1.2578 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | no restrictions. |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | pK1:4.50;pK2:15 (25°C) |
| form | Crystalline |
| color | Black powder |
| Water Solubility | Soluble in ethanol, chloroform, dimethylsulfoxide, and pyridine. Insoluble in water. |
| Merck | 14,3377 |
| BRN | 748838 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 60-10-6(CAS DataBase Reference) |
| FDA UNII | NJZ2CJ4D6P |
| EPA Substance Registry System | Diazenecarbothioic acid, phenyl-, 2-phenylhydrazide (60-10-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 36-26 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LQ9450000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
Dithizone price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | DX2370 | Dithizone Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS | 60-10-6 | 25g | $981 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1.03092 | Dithizone for analysis (1,5-diphenylthiocarbazone) Reag. Ph Eur | 60-10-6 | 5G | $158 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1.03092 | Dithizone for analysis (1,5-diphenylthiocarbazone) Reag. Ph Eur | 60-10-6 | 25g | $396 | 2024-03-01 | Buy |
| TCI Chemical | D0949 | Dithizone >85.0%(E) | 60-10-6 | 25g | $97 | 2024-03-01 | Buy |
| Alfa Aesar | 033283 | Dithizone, ACS, 85+% | 60-10-6 | 2g | $21.65 | 2024-03-01 | Buy |
Dithizone Chemical Properties,Uses,Production
Chemical Properties
dark brown or black crystals
Uses
Dithizone is an organosulfur compound that acts as a chelating agent and forms complexes with metals such as lead and mercury. Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes.
Uses
Dithizone is used as an indicator for minute amounts of lead. It acts as a chelating agent for heavy metal poisoning. As a ligand, it forms complexes with metals like zinc, lead and mercury. Further, it is used to assess the purity of human pancreatic islet preparations, which is used for transplantation in patients with type 1 diabetes. In addition to this, it is used as a titrant in the quantitative determination of heavy metals.
Uses
Sensitive reagent for several heavy metals, Co, Cu, Pb, and Hg; especially for the estimation of minute amounts of Pb.
Definition
ChEBI: Dithizone is a member of phenylhydrazines.
General Description
Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals.
Purification Methods
The crude dithizone is dissolved in CCl4 to give a concentrated solution. This is filtered through a sintered glass funnel and shaken with 0.8M aqueous ammonia to extract dithizonate ion. The aqueous layer is washed with several portions of CCl4 to remove undesirable materials. The aqueous layer is acidified with dilute H2SO4 to precipitate pure dithizone. This is dried in a vacuum. When only small amounts of dithizone are required, purification by paper chromatography is convenient. [Cooper & Hibbits J Am Chem Soc 75 5084 1933.] Instead of CCl4, CHCl3 can be used, and the final extract, after washing with water, can be evaporated in air at 40-50o and dried in a desiccator. It complexes with Cd, Hg, Ni and Zn. [Beilstein 16 H 26, 16 IV 18.]
Dithizone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Shenyang Simchoice Chemical Co.,Ltd | +86-024-23769576 +86-15040101888 | sales@simchoicechem.com | China | 255 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12431 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from Dithizone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-02-19 | Dithizone
60-10-6
|
US $250.00 / g | 1g | 96 | 500 Kg | R&D Scientific Inc. | |
 |
2023-08-01 | Dithizone
60-10-6
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-03-16 | Dithizone
60-10-6
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Guanlang Biotechnology Co., Ltd. |