ChemicalBook >> CAS DataBase List >>ITE
ITE
- CAS No.
- 448906-42-1
- Chemical Name:
- ITE
- Synonyms
- ITE;ARYL HYDROCARBON RECEPTOR LIGAND;ITE,Aryl Hydrocarbon Receptor,Inhibitor,inhibit,AhR;Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate;2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID;methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate;2-(1H-INDOL-3-YLCARBONYL)-4-THIAZOLECARBOXYLIC ACID METHYL ESTER;2-(1'H-indole-37-carbonyl)-thiasole-4-carboxylic acid methyl ester;4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester
- CBNumber:
- CB5754713
- Molecular Formula:
- C14H10N2O3S
- Molecular Weight:
- 286.31
- MDL Number:
- MFCD06411597
- MOL File:
- 448906-42-1.mol
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H319-H315 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
ITE price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1803 | ITE ≥98%(HPLC) | 448906-42-1 | 10 | $231 | 2021-12-16 | Buy |
| Usbiological | 452797 | ITE | 448906-42-1 | 1mg | $305 | 2021-12-16 | Buy |
| TRC | I942030 | ITE | 448906-42-1 | 1mg | $45 | 2021-12-16 | Buy |
| ChemScene | CS-5141 | ITE 99.27% | 448906-42-1 | 5mg | $119 | 2021-12-16 | Buy |
| ApexBio Technology | A8615 | ITE | 448906-42-1 | 10mg | $158 | 2021-12-16 | Buy |
ITE Chemical Properties,Uses,Production
Uses
ITE is an endogenous AHR ligand that parenterally or orally induces FoxP3+ Treg that suppress exprimental autoimmune encephalomyelitis. ITE promotes the induction of active immunology tolerance and identifies nontoxic endogenous AHR ligands.
Definition
ChEBI: 2-[1H-indol-3-yl(oxo)methyl]-4-thiazolecarboxylic acid methyl ester is an indolyl carboxylic acid.
Biological Activity
Endogenous agonist for the transcription factor aryl hydrocarbon receptor (AHR); K i = 3 nM for binding to murine AHR. Transactivates DRE-containing reporter gene constructs in Hepa1c1c7 cells ~ 5-fold more potently than β -naphthoflavone. Active in vivo .
storage
Store at RT
ITE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 93)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
448906-42-1(ITE)Related Search:
ITE
2-(1H-INDOL-3-YLCARBONYL)-4-THIAZOLECARBOXYLIC ACID METHYL ESTER
2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID
2-(1'H-indole-37-carbonyl)-thiasole-4-carboxylic acid methyl ester
Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate
methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate
ARYL HYDROCARBON RECEPTOR LIGAND
4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester
ITE,Aryl Hydrocarbon Receptor,Inhibitor,inhibit,AhR
448906-42-1
C14H10N2O3S