HUMAN PDGF-BB
- CAS No.
- Chemical Name:
- HUMAN PDGF-BB
- Synonyms
- PDGF-BB;RHPDGF-BB;HPDGF-B/B;HUMAN GDGF-BB;HUMAN PDGF-BB;PDGF-BB, HUMAN;PDGF-BB from mouse;PDGF-AA from mouse;REC PDGF BB (HUMAN);PDGF-BB PROTEIN, HUMAN
- CBNumber:
- CB5773484
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00213023
- MOL File:
- Mol file
HUMAN PDGF-BB price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3229 | PDGF-BB from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 10μG | $347 | 2024-03-01 | Buy | |
| Sigma-Aldrich | P3201 | Platelet-Derived Growth Factor-BB human PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture | 10μG | $371 | 2024-03-01 | Buy | |
| Sigma-Aldrich | P3201 | Platelet-Derived Growth Factor-BB human PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture | 50μG | $1120 | 2024-03-01 | Buy | |
| Usbiological | 156372 | Platelet Derived Growth Factor BB | 10ug | $333 | 2021-12-16 | Buy | |
| Usbiological | P4258-17A | Platelet Derived Growth Factor BB | 50ug | $340 | 2021-12-16 | Buy |
HUMAN PDGF-BB Chemical Properties,Uses,Production
Uses
Platelet-Derived Growth Factor-BB human has been used :
- As a growth supplement in proximal tubule and glomerular explant cell culture
- In three-dimensional scaffold preparation
- To study the effect of brivanib on growth factor signaling pathways
- In transwell migration assay
General Description
Platelet-derived growth factor (PDGF) is expressed as homo and heterodimers : PDGF-AB FDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD. The PDGF gene is highly conserved mapped to human chromosome 7p22.3. The active form of Pdgf exists as disulfide-linked dimers. It consists of cystine-knot-fold growth factor domain, which is highly conserved, except for the N-terminal prodomain, which shows variation in length among the isoforms.
Biochem/physiol Actions
The three naturally occurring PDGFs (platelet-derived growth factors); PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Heterozygous mutation in PDGFB is associated with primary familial brain calcification. It is also associated with angiogenesis for osteogenesis. PDGFB induces migration of endothelial progenitor cells and mesenchymal stem cells.
HUMAN PDGF-BB Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN PDGF-BB Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Chengdu Jinglin Biotechnology Co., Ltd. | 17711399154 | 3211919385@qq.com | China | 1815 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696; | info@hanhongsci.com | China | 42982 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Chengdu Youngshe Chemical Co., Ltd. | 028-62328193 17380623303 | Caroline@youngshechem.com | China | 2348 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9617 | 58 |