N6-CYCLOPENTYLADENOSINE
- CAS No.
- 41552-82-3
- Chemical Name:
- N6-CYCLOPENTYLADENOSINE
- Synonyms
- UK-80882;N-CYCLOPENTYLADENOSINE;N6-CYCLOPENTYLADENOSINE;Adenosine, N-cyclopentyl-;N6-Cyclopentyladenosine,CPA;N(sup 6)-cyclopentyladenosine;N6-Cyclopentyladenosine;N6 Cyclopentyladenosine,N6Cyclopentyladenosine,N-6-Cyclopentyladenosine;(2R,3R,4S,5R)-2-(6-(CyclopentylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
- CBNumber:
- CB5779284
- Molecular Formula:
- C15H21N5O4
- Molecular Weight:
- 335.36
- MDL Number:
- MFCD00036845
- MOL File:
- 41552-82-3.mol
- MSDS File:
- SDS
| Melting point | 78.8 °C |
|---|---|
| Boiling point | 673.4±65.0 °C(Predicted) |
| Density | 1.78±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble1.7mg/mL |
| pka | 13.12±0.70(Predicted) |
| form | solid |
| color | white to off-white |
| FDA UNII | 7LG47VG1ID |
N6-CYCLOPENTYLADENOSINE price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C8031 | N6-Cyclopentyladenosine solid | 41552-82-3 | 25mg | $82.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | C8031 | N6-Cyclopentyladenosine solid | 41552-82-3 | 100mg | $249 | 2024-03-01 | Buy |
| Sigma-Aldrich | 119135 | Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem | 41552-82-3 | 25MG | $89.9 | 2024-03-01 | Buy |
| Cayman Chemical | 21448 | N6-Cyclopentyladenosine ≥99% | 41552-82-3 | 10mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21448 | N6-Cyclopentyladenosine ≥99% | 41552-82-3 | 50mg | $116 | 2024-03-01 | Buy |
N6-CYCLOPENTYLADENOSINE Chemical Properties,Uses,Production
Uses
N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist with Ki values of 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively and EC50 value of 18600 nM for hA2B. It has also shown its efficacy against organophosphate toxcity.
Uses
N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.
Biological Activity
Potent and selective adenosine A 1 receptor agonist (K i values are 2.3, 790 and 43 nM for human A 1 , A 2A and A 3 receptors respectively; EC 50 = 18600 nM for hA 2B ). Centrally active following systemic administration in vivo .
Biochem/physiol Actions
N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.
storage
Desiccate at +4°C
N6-CYCLOPENTYLADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
N6-CYCLOPENTYLADENOSINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 10027 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |