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(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL structure

CAS No.: 14774-37-9

Chemical Name:: (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL

Synonyms: TETRAHYDROPYRAN-4-METHANOL;oxan-4-ylMethanol;15N]-Ammonium Chloride;Tetrahydropyran-4-Methano;TERTAHYDROPYRAN-4-METHANOL;4-(Hydroxymethyl)tetrahyd...;4-(Hydroxymethyl)tetrahydropyr;Tetrahydropyran-4-methanol?New;4-(Hydroxymethyl)tetrahydropyran;(TETRAHYDRO-PYRAN-4-YL)-METHANOL

CBNumber:: CB5780709

Molecular Formula:: C6H12O2

Molecular Weight:: 116.16

MDL Number:: MFCD00457804

MOL File:: 14774-37-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:59:17

Product description	Number	Pack Size	Price
Tetrahydropyran-4-methanol >97.0%(GC)	T2965	1g	$59
Tetrahydropyran-4-methanol min. 97.0 %	T2965	5G	$378
4-HYDROXYMETHYLTETRAHYDROPYRAN 97%	66550	5G	$26
4-HYDROXYMETHYLTETRAHYDROPYRAN 97%	66550	25G	$78
4-HYDROXYMETHYLTETRAHYDROPYRAN 97%	66550	100G	$210
More product size

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(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL Properties

Boiling point	105 °C
Density	1.000±0.06 g/cm3(Predicted)
Flash point	61°(142°F)
refractive index	1.4600
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
pka	14.85±0.10(Predicted)
color	Colorless to Light yellow to Light orange
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C6H12O2/c7-5-6-1-3-8-4-2-6/h6-7H,1-5H2
InChIKey	YSNVSVCWTBLLRW-UHFFFAOYSA-N
SMILES	C1OCCC(CO)C1
CAS DataBase Reference	14774-37-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Warning

Hazard statements

H227-H315-H318-H335

Precautionary statements

P210e-P261-P280a-P305+P351+P338-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-22-41-37/38

Safety Statements

26-36/37/39-23-39

HazardClass

IRRITANT

HS Code

29329990

NFPA 704

	1
2		0

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T2965	Tetrahydropyran-4-methanol >97.0%(GC)	14774-37-9	1g	$59	2026-04-30	Buy
TCI Chemical	T2965	Tetrahydropyran-4-methanol min. 97.0 %	14774-37-9	5G	$378	2026-04-30	Buy
AstaTech	66550	4-HYDROXYMETHYLTETRAHYDROPYRAN 97%	14774-37-9	5G	$26	2026-04-30	Buy
AstaTech	66550	4-HYDROXYMETHYLTETRAHYDROPYRAN 97%	14774-37-9	25G	$78	2026-04-30	Buy
AstaTech	66550	4-HYDROXYMETHYLTETRAHYDROPYRAN 97%	14774-37-9	100G	$210	2026-04-30	Buy

Product number	Packaging	Price	Buy
T2965	1g	$59	Buy
T2965	5G	$378	Buy
66550	5G	$26	Buy
66550	25G	$78	Buy
66550	100G	$210	Buy

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

Used as a reagent in the identification and optimization of pteridinone Toll-like receptor 7 agonists, which can be used for the oral treatment of viral hepatitis. 4-(Hydroxymethyl)tetrahydropyran is also a starting material for [1-[(Tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone which is a drug that acts as CB2 cannabinoid receptor agonist.

Synthesis

96835-17-5

14774-37-9

Ethyl tetrahydro-2H-pyran-4-carboxylate (5.0 g, 34.7 mmol) was slowly added to a stirred suspension of lithium aluminum hydride (LiAlH4, 4.0 g, 104 mmol) in tetrahydrofuran (THF, 100 mL) at 0 °C. The reaction mixture was kept stirred at 0 °C for 1 hour. Subsequently, ethyl acetate (20 mL) was added slowly and dropwise to the reaction mixture to quench the excess LiAlH4, followed by the addition of 10% aqueous sodium hydroxide (NaOH). The resulting mixture was continued to be stirred for 30 minutes. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove insoluble impurities. The filtrate was concentrated under reduced pressure to give the target product (tetrahydro-2H-pyran-4-yl) methanol (9) as a colorless oil. The yield was 3.9 g in 96% yield. The product was characterized by 1H NMR (400 MHz, DMSO-d5): δ 4.46 (broad single peak, 1H), 3.82 (double peak, J=8.0 Hz, 2H), 3.25-3.22 (multiple peaks, 4H), 1.62-1.52 (multiple peaks, 3H), 1.18-1.04 (multiple peaks, 1H).

References

[1] Patent: US2014/275043, 2014, A1. Location in patent: Paragraph 0415; 0416
[2] Justus Liebigs Annalen der Chemie, 1936, vol. 525, p. 292,294
[3] Patent: WO2010/96371, 2010, A2. Location in patent: Page/Page column 156

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL synthesis

Synthesis of (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL from Ethyl Tetrahydropyran-4-Carboxylate

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL Preparation Products And Raw materials

Raw materials

Ethanol Potassium hydroxide Acetone Sodium Tetrahydro-2H-pyran-4-carboxylic acid

2,2'-Dichlorodiethyl ether Tetrahydrofuran Lithium Aluminum Hydride Diethyl malonate Methyl tetrahydropyran-4-carboxylate

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Preparation Products

Tetrahydropyran-4-carbaldehyde 1-azabicyclo[2.2.1]heptane 4-(Iodomethyl)tetrahydro-2H-pyran Tetrahydropyranyl-4-acetic acid 4-(Bromomethyl)tetrahydropyran

Tetrahydro-2H-pyran-2-ylmethyl 4-methylbenzenesulfonate

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(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL Suppliers

Global( 280)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Springchem New Material Technology Co.,Limited	+86-021-62885108 +8613917661608	info@spring-chem.com	China	2068	57
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13843	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Springchem New Material Technology Co.,Limited	57
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

View Lastest Price from (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL 14774-37-9	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2025-09-25	(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL 14774-37-9	US $31.00-1.50 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2025-04-04	Tetrahydropyran-4-methanol 14774-37-9	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL
14774-37-9
US $1.10 / g
99.00%
Dideu Industries Group Limited

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL
14774-37-9
US $31.00-1.50 / kg
99%
Henan Fengda Chemical Co., Ltd

Tetrahydropyran-4-methanol
14774-37-9
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL Spectrum

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL(14774-37-9)¹HNMR

14774-37-9((TETRAHYDRO-2H-PYRAN-4-YL)METHANOL)Related Search:

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FUSARENON X scirpentriol 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE 9,21-DEHYDRORYANODINE NEOSOLANIOL

4-phenyltetrahydropyran-4-carboxylic acid RORIDIN A NIVALENOL

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(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL (TETRAHYDRO-PYRAN-4-YL)-METHANOL TERTAHYDROPYRAN-4-METHANOL 4-(Hydroxymethyl)tetrahydro-2H-pyran 4-(Hydroxymethyl)tetrahydropyr (Tetrahydro-pyran-4-yl)-methanol ,97% oxan-4-ylMethanol 4-(Hydroxymethyl)tetrahydropyran 4-(Hydroxymethyl)tetrahyd... tetrahydro-2H-pyran-4-ylmethanol(SALTDATA: FREE) (TETRAHYDRO-2H-PYRAN-4-YL)METHANO (Tetrahydro-2H-pyran-4-yl)methanol, (Oxan-4-yl)methanol Tetrahydropyran-4-Methano (Terahydro-2H-pyran-4-yl)methanol 4-(Hydroxymethyl)tetrahydro-2H-pyran98% 15N]-Ammonium Chloride 2H-Pyran-4-methanol, tetrahydro- (tetrahydrogen-2h-pyran-4-yl) methanol " Tetrahydro-4-hydroxymethyl-2H-pyran (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL ISO 9001：2015 REACH TETRAHYDROPYRAN-4-METHANOL Tetrahydropyran-4-methanol?New Chemicalbook4-(Hydroxymethyl)tetrahydro-2H-pyran 4-(Hydroxymethyl)tetrahydropyran, 98% Tetrahydropyran-4-methanol (Tetrahydro-2H-pyran-4-yl)methanol 14774-37-9 Pyrans, Piperidines &Piperazines Pyrans, Piperidines & Piperazines Heterocycles series Hydroxymethyl's Alcohols and Derivatives blocks Heterocycles