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PROTAC IAP binding moiety 2

PROTAC IAP binding moiety 2 structure

CAS No.: 2095244-62-3

Chemical Name:: PROTAC IAP binding moiety 2

Synonyms: MV-1-NH-Me;PROTAC IAP binding moiety 2;(2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-N-methyl-3,3-diphenylpropanamide;(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(2S)-1-(methylamino)-1-oxo-3,3-diphenylpropan-2-yl]pyrrolidine-2-carboxamide

CBNumber:: CB58054811

Molecular Formula:: C33H45N5O4

Molecular Weight:: 575.74

MDL Number:: MFCD32062716

MOL File:: Mol file

Last updated:2025-04-18 09:51:11

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PROTAC IAP binding moiety 2 Properties

Boiling point	886.5±65.0 °C(Predicted)
Density	1.167±0.06 g/cm3(Predicted)
pka	12.80±0.20(Predicted)

PROTAC IAP binding moiety 2 Chemical Properties,Uses,Production

Uses

MV-1-NH-Me, the MV-1 based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER[1].

IC 50

cIAP1

References

[1] Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666. DOI:10.1111/cas.13284

PROTAC IAP binding moiety 2 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC IAP binding moiety 2 Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32376	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7786	56
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1601	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	9070	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	26070	58
Biosynth Biological Technology (Suzhou) Co Ltd	51288865780	sales@biosynth.com	China	6051	58
Adooq Bioscience LLC	400-025-6535	sales@adooq.cn	China	6215	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Jilin Province Woda Biotechnology Co., Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Biosynth Biological Technology (Suzhou) Co Ltd	58
Adooq Bioscience LLC	58

MV-1-NH-Me PROTAC IAP binding moiety 2 (2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(2S)-1-(methylamino)-1-oxo-3,3-diphenylpropan-2-yl]pyrrolidine-2-carboxamide (2S)-2-{[(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]pyrrolidin-2-yl]formamido}-N-methyl-3,3-diphenylpropanamide 2095244-62-3