ChemicalBook >> CAS DataBase List >>(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- CAS No.
- 1227675-51-5
- Chemical Name:
- (6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- Synonyms
- SCH 39166 HYDROBROMIDE;(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
- CBNumber:
- CB5828599
- Molecular Formula:
- C19H21BrClNO
- Molecular Weight:
- 394.74
- MDL Number:
- MFCD08703109
- MOL File:
- Mol file
Last updated:2023-06-30 15:45:59
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2591 | SCH-39166 hydrobromide ≥98% (HPLC) | 1227675-51-5 | 5MG | $123 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2591 | SCH-39166 hydrobromide ≥98% (HPLC) | 1227675-51-5 | 25MG | $495 | 2024-03-01 | Buy |
Cayman Chemical | 25331 | SCH 39166 (hydrobromide) ≥98% | 1227675-51-5 | 1mg | $40 | 2024-03-01 | Buy |
Cayman Chemical | 25331 | SCH 39166 (hydrobromide) ≥98% | 1227675-51-5 | 5mg | $158 | 2024-03-01 | Buy |
Cayman Chemical | 25331 | SCH 39166 (hydrobromide) ≥98% | 1227675-51-5 | 10mg | $276 | 2024-03-01 | Buy |
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Chemical Properties,Uses,Production
Description
SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol intake in Sardinian alcohol-preferring rats and sucrose intake in water-deprived and water-sated rats without affecting food or total fluid intake. SCH 39166 also suppresses cocaine-induced arrhythmias in anesthetized dogs.
Uses
SCH 39166 is a dopamine D1/D5 receptor antagonist used in the treatment of schizophrenia, cocaine addiction and obesity.
storage
Desiccate at RT
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE Suppliers
Global( 15)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
SCH 39166 HYDROBROMIDE
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE
1227675-51-5
C19H20ClNOHBr
Dopamine receptor