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ChemicalBook >> CAS DataBase List >>2,5-Pyrrolidinedione, 3-amino-, (3R)-

2,5-Pyrrolidinedione, 3-amino-, (3R)-

2,5-Pyrrolidinedione, 3-amino-, (3R)- Structure
2,5-Pyrrolidinedione, 3-amino-, (3R)- structure
CAS No.
404887-22-5
Chemical Name:
2,5-Pyrrolidinedione, 3-amino-, (3R)-
Synonyms
(R)-Aspartimide;3R-amino-2,5-pyrrolidinedione;(R)-3-Aminopyrrolidine-2,5-dione;2,5-Pyrrolidinedione, 3-amino-, (3R)-
CBNumber:
CB58373448
Molecular Formula:
C4H6N2O2
Molecular Weight:
114.1
MDL Number:
MFCD19207316
MOL File:
404887-22-5.mol
Last updated:2023-04-23 13:52:06
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2,5-Pyrrolidinedione, 3-amino-, (3R)- Properties

Boiling point 337.0±35.0 °C(Predicted)
Density 1.337±0.06 g/cm3(Predicted)
pka 8.93±0.50(Predicted)
form A solid

2,5-Pyrrolidinedione, 3-amino-, (3R)- Chemical Properties,Uses,Production

Description

(R)-Aspartimide is a byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides.1 Aspartimide is formed by cyclization of aspartic acid during Fmoc removal or peptide coupling.2

References

1. Ruczyński, J., Lewandowska, B., Mucha, P., et al. Problem of aspartimide formation in Fmoc-based solid-phase peptide synthesis using Dmab group to protect side chain of aspartic acid J. Pept. Sci. 14(3),335-341(2008).
2. Neumann, K., Farnung, J., Baldauf, S., et al. Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups Nat. Commun. 11(1),982(2020).

2,5-Pyrrolidinedione, 3-amino-, (3R)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Pyrrolidinedione, 3-amino-, (3R)- Suppliers

Global( 9)Suppliers
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BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1294 58
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Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 13331045123 sales@peking-pharmacy.com China 9997 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
BOC Sciences 65
Jilin Province Woda Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Changzhou Furuisi Biotechnology Co., Ltd 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Beijing Biocreative Technology Co., Ltd. 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
2,5-Pyrrolidinedione, 3-amino-, (3R)- (R)-Aspartimide (R)-3-Aminopyrrolidine-2,5-dione 3R-amino-2,5-pyrrolidinedione 404887-22-5