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RS 504393

RS 504393 Structure
RS 504393 structure
CAS No.
300816-15-3
Chemical Name:
RS 504393
Synonyms
RS 504393;RS-504393; RS504393;RS504393 >=98% (HPLC);6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir...;CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393;6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin];6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2(;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one;6-Methyl-1'-(2-(5-Methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one
CBNumber:
CB5837883
Molecular Formula:
C25H27N3O3
Molecular Weight:
417.5
MDL Number:
MFCD09038564
MOL File:
300816-15-3.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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RS 504393 Properties

Density 1.28
storage temp. 2-8°C
solubility DMSO: soluble1mg/mL, clear (warmed)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

RS 504393 price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0711 RS504393 ≥98% (HPLC) 300816-15-3 5mg $152 2024-03-01 Buy
Sigma-Aldrich SML0711 RS504393 ≥98% (HPLC) 300816-15-3 25mg $633 2024-03-01 Buy
Cayman Chemical 17330 RS 504393 ≥98% 300816-15-3 1mg $45 2024-03-01 Buy
Cayman Chemical 17330 RS 504393 ≥98% 300816-15-3 5mg $121 2024-03-01 Buy
Cayman Chemical 17330 RS 504393 ≥98% 300816-15-3 10mg $198 2024-03-01 Buy
Product number Packaging Price Buy
SML0711 5mg $152 Buy
SML0711 25mg $633 Buy
17330 1mg $45 Buy
17330 5mg $121 Buy
17330 10mg $198 Buy

RS 504393 Chemical Properties,Uses,Production

Uses

RS 504393 is a small molecule antagonist at the CC chemokine receptor 2.

Uses

RS504393 has been used in mass spectrometry.

Definition

ChEBI: 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-2-spiro[1H-3,1-benzoxazine-4,4'-piperidine]one is a member of 1,3-oxazoles.

Biological Activity

Extremely selective CCR2 chemokine receptor antagonist (IC 50 values are 98 nM and > 100 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC 50 = 330 nM) and ischemia-reperfusion injury in kidneys.

Biochem/physiol Actions

RS504393 is a highly selective CCR2 chemokine receptor antagonist. RS504393 inhibits MCP-1 chemotaxis and ischemia-reperfusion injury in kidneys.

storage

Store at +4°C

RS 504393 Preparation Products And Raw materials

Raw materials

Preparation Products

RS 504393 Suppliers

Global( 87)Suppliers
Supplier Tel Email Country ProdList Advantage
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 967 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Pharmahands (Taizhou) Co., Ltd. 		+86 523-86200360 CHINA 358 58
Apeloa Pharmaceutical Co., Ltd. 		+86-0571-87635730 +8615858229168 chem1022@hengdian-group.com China 1469 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9425 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Supplier Advantage
Biochempartner 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Pharmahands (Taizhou) Co., Ltd. 		58
Apeloa Pharmaceutical Co., Ltd. 		58
InvivoChem 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Henan Aochuang Chemical Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from RS 504393 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RS 504393 pictures 2022-09-08 RS 504393
300816-15-3
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
RS 504393 pictures 2020-01-13 RS 504393
300816-15-3
 US $5.50 / KG 1IU 98%min 1kg-100kg Career Henan Chemical Co
  • RS 504393 pictures
  • RS 504393
    300816-15-3
  • US $0.00-0.00 / kg
  • 98%
  • Henan Aochuang Chemical Co.,Ltd.
  • RS 504393 pictures
  • RS 504393
    300816-15-3
  • US $5.50 / KG
  • 98%min
  • Career Henan Chemical Co

RS 504393 Spectrum

RS 504393(300816-15-3)1HNMR

300816-15-3(RS 504393)Related Search:

Octadecyl methacrylate 2-Methylpropanedioic acid p-Tolualdehyde (S)-(+)-Benzyl glycidyl ether Benzyl alcohol
4'-Hydroxyacetophenone RS 504393 SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE

1of2

Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]- 6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi 6-Methyl-1'-(2-(5-Methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one 6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2( 6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin] RS 504393 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one RS-504393; RS504393 RS504393 >=98% (HPLC) 6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir... CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393 6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one 300816-15-3