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Diisopropylamine structure
Chemical Name:
DIPA;(iso-C3H7)2NH;AURORA KA-7634;Diisopropylamin;Diisoproplamine;DIISOPROPYLAMINE;Isodipropylamine;diisopropylanmine;Bis(isopropyl)amine;N,N-Diisopropylamine
Molecular Formula:
Formula Weight:
MOL File:

Diisopropylamine Properties

Melting point:
-61 °C
Boiling point:
84 °C(lit.)
0.722 g/mL at 25 °C(lit.)
vapor density 
3.5 (vs air)
vapor pressure 
50 mm Hg ( 20 °C)
refractive index 
n20/D 1.392(lit.)
Flash point:
1.4 °F
storage temp. 
Store at RT.
100 g/L (20°C)
11.05(at 25℃)
Clear colorless
11.8 (6g/l, H2O, 20℃)
explosive limit
Water Solubility 
100 g/L (20 ºC)
Exposure limits
NIOSH REL: TWA 5 ppm (20 mg/m3), IDLH 200 ppm; OSHA PEL: TWA 5 ppm; ACGIH TLV: TWA 5 ppm (adopted).
Stable. Flammable. Incompatible with strong oxidizing agents. May react violently with strong acids or oxidizers. Air sensitive.
CAS DataBase Reference
108-18-9(CAS DataBase Reference)
NIST Chemistry Reference
2-Propanamine, N-(1-methylethyl)-(108-18-9)
EPA Substance Registry System
2-Propanamine, N-(1-methylethyl)-(108-18-9)
  • Risk and Safety Statements
Signal word  Danger
Hazard statements  H318-H225-H302-H314-H331
Precautionary statements  P260h-P405-P501a-P210-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P403+P233
Hazard Codes  F,C
Risk Statements  11-20/22-34
Safety Statements  16-26-36/37/39-45
RIDADR  UN 1158 3/PG 2
WGK Germany  2
RTECS  IM4025000
Autoignition Temperature 599 °F
Hazard Note  Highly Flammable/Corrosive/Harmful
HS Code  2921 19 99
HazardClass  3
PackingGroup  II
Toxicity LD50 orally in rats: 0.77 g/kg (Smyth)

NFPA 704

Diamond Hazard Value Description
Flammability   3 Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

Diisopropylamine price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 38290 Diisopropylamine puriss. p.a., ≥99.0% (GC) 108-18-9 250ml-f $40.1 2018-11-20 Buy
Sigma-Aldrich 38290 Diisopropylamine puriss. p.a., ≥99.0% (GC) 108-18-9 1l-f $126 2018-11-20 Buy
Alfa Aesar A10280 Diisopropylamine, 99+% 108-18-9 2500ml $82.7 2018-11-13 Buy
Alfa Aesar A10280 Diisopropylamine, 99+% 108-18-9 500ml $26.4 2018-11-13 Buy
Sigma-Aldrich 471224 Diisopropylamine ≥99.5% 108-18-9 100ml $29.5 2018-11-20 Buy

Diisopropylamine Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Physical properties

Colorless liquid with an ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 50 μg/m3 (130 ppbv) and 190 μg/m3 (380 ppbv), respectively (Hellman and Small, 1974).

Production Methods

Diisopropylamine is produced by the reaction of diisopropyl alcohol with ammonia (HSDB 1989).

General Description

A clear colorless liquid with an ammonia-like odor. Flash point 30°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Soluble in water. Sensitive to heat and air.

Reactivity Profile

Diisopropylamine can react violently with oxidizing agents and strong acids. Readily eutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation of vapors causes irritation, sometimes with nausea and vomiting; can also cause burns to the respiratory system. Ingestion causes irritation of mouth and stomach. Vapor irritates eyes; liquid causes severe burn, like caustic. Contact with skin causes irritation.

Health Hazard

In humans, diisopropylamine is an eye irritant. When exposed to concentrations between 25 and 50 p.p.m., workers complained of disturbances of vision. There were also complaints of nausea and headache. Dermatitis would be expected from prolonged skin exposure (Beard and Noe, 1981).

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Industrial uses

Diisopropylamine is used as a catalyst and as a stabilizer for mesityl oxide (HSDB 1989). It is also used as an intermediate in the synthesis of dyes, pharmaceuticals and pesticides (e.g. Diallate, Fenamiphos and Triallate).

Safety Profile

Moderately toxic by ingestion and subcutaneous routes. Mildly toxic by inhalation. Mutation data reported. A skin and severe eye irritant. Inhalation of fumes can cause pulmonary edema. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use alcohol foam,foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx See also AMINES.

Environmental Fate

Photolytic. Low et al. (1991) reported that the photooxidation of aqueous secondary amine solutions by UV light in the presence of titanium dioxide resulted in the formation of ammonium and nitrate ions.
Chemical/Physical. Reacts with acids forming water-soluble salts.


Little, if any investigation of the metabolism of short-chain aliphatic amines has been reported and the best that can be done is to suggest some possible metabolic routes. For example the flavin monooxygenase system could produce the hydroxylamine through N-hydroxylation catalyzed by the flavin monooxygenase system (Ziegler 1988). N-hydroxylation can also be induced with the cytochrome P-450 system as can N-dealkylation reactions (Lindeke and Cho 1982). More definitive analysis must await experimental studies.

Purification Methods

Distil the amine from NaOH, or reflux it three minutes over Na wire or NaH, and distil it into a dry receiver under N2. [Beilstein 4 H 154, 4 I 369, 4 II 630, 4 III 274, 4 IV 510.]

Diisopropylamine Preparation Products And Raw materials

Raw materials

Preparation Products

Diisopropylamine Suppliers

Global( 260)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 CHINA 1365 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32447 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1861 55
Hebei Chisure Biotechnology Co., Ltd.
0311 66567340 CHINA 1017 58
career henan chemical co
+86-371-86658258 CHINA 30002 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 23976 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28236 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 8921 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114 CHINA 6372 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23049 58

View Lastest Price from Diisopropylamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-09 Diisopropylamine
US $2.00 / KG 1KG 99% customise career henan chemical co
2019-05-06 Diisopropylamine
US $10.00 / KG 1KG 99% 500tons/month Hebei Chisure Biotechnology Co., Ltd.
2019-03-08 Diisopropylamine
US $0.00 / L 200L 99% 1000MT Hefei TNJ Chemical Industry Co.,Ltd.

Diisopropylamine Spectrum

108-18-9(Diisopropylamine)Related Search:

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