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mefruside

CAS No.
7195-27-9
Chemical Name:
mefruside
Synonyms
B 1500;FDA 1902;FBA 1500;Baycaron;BAY 1500;Mefrusid;mefruside;Valine Impurity 35;mefruside USP/EP/BP;N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine
CBNumber:
CB5875654
Molecular Formula:
C13H19ClN2O5S2
Molecular Weight:
382.88
MDL Number:
MFCD00867319
MOL File:
7195-27-9.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:41

mefruside Properties

Melting point 149.5°C
Boiling point 565.2±60.0 °C(Predicted)
Density 1.3150 (rough estimate)
refractive index 1.6100 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.26±0.60(Predicted)
color White to Pale Beige
Stability Hygroscopic
FDA UNII X1NS9SNS92
ATC code C03BA05

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word  Warning
Hazard statements  H373-H315-H335-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P260-P314-P501-P264-P280-P302+P352-P321-P332+P313-P362
Toxicity LD50 oral in rabbit: > 3gm/kg

mefruside price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M205150 Mefruside 7195-27-9 5mg $260 2021-12-16 Buy
American Custom Chemicals Corporation API0011858 MEFRUSIDE 95.00% 7195-27-9 1MG $329.7 2021-12-16 Buy
American Custom Chemicals Corporation API0011858 MEFRUSIDE 95.00% 7195-27-9 5MG $502.29 2021-12-16 Buy
Medical Isotopes, Inc. 59614 Mefruside 7195-27-9 1mg $650 2021-12-16 Buy
Product number Packaging Price Buy
M205150 5mg $260 Buy
API0011858 1MG $329.7 Buy
API0011858 5MG $502.29 Buy
59614 1mg $650 Buy

mefruside Chemical Properties,Uses,Production

Originator

Baycaron,Bayer,W. Germany,1967

Uses

Mefruside is a diuretic used for the treatment of edema and hypertension.

Definition

ChEBI: Mefruside is an organic molecular entity.

Manufacturing Process

By hydrogenation of α-methyl-α-cyanotetrahydrofuran with Raney nickel as catalyst, α-methyl-α-tetrahydrofurfuryl amine is obtained (BP 48°C/12 mm Hg) which is alkylated by dimethyl sulfate to give α-methyl-αtetrahydrofurfurylmethylamine (BP 70°C/40 mm Hg). The amine is then reacted with 4-chloro-3-sulfamyl benzene sulfochloride in the presence of an acid acceptor. The mixture is stirred overnight, the solvent (acetone or pyridine) is driven off under vacuum and the residue is recrystallized from alcohol.

Therapeutic Function

Diuretic

mefruside Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3791 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29474 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118 xie@china-sinoway.com China 992 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55672 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 1052@dideu.com China 10009 58

View Lastest Price from mefruside manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
mefruside pictures 2021-07-20 mefruside
7195-27-9
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
mefruside USP/EP/BP pictures 2021-07-09 mefruside USP/EP/BP
7195-27-9
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
  • mefruside pictures
  • mefruside
    7195-27-9
  • US $1.00-1.00 / KG
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd
1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]- (9CI) 4-Chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)-m-benzenedisulfonamide B 1500 BAY 1500 Baycaron FBA 1500 FDA 1902 m-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)- (7CI, 8CI) N-(4'-Chloro-3'-sulfamoylbenzenesulfonyl)-N-methyl-2-aminomethyl-2-methyltetrahydrofuran N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine mefruside 4-Chloro-N-methyl-N-(tetrahydro-2-methylfuran-2-yl)-1,3-benzenedisulfonamide Mefrusid 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide 4-chloro-N1-methyl-N1-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide 4-chloro-N-methyl-N-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide mefruside USP/EP/BP 1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]- Valine Impurity 35 7195-27-9 C13H19ClN2O5S2