ChemicalBook >> CAS DataBase List >>mefruside
mefruside
- CAS No.
- 7195-27-9
- Chemical Name:
- mefruside
- Synonyms
- B 1500;FDA 1902;FBA 1500;Baycaron;BAY 1500;Mefrusid;mefruside;Valine Impurity 35;mefruside USP/EP/BP;N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine
- CBNumber:
- CB5875654
- Molecular Formula:
- C13H19ClN2O5S2
- Molecular Weight:
- 382.88
- MDL Number:
- MFCD00867319
- MOL File:
- 7195-27-9.mol
- MSDS File:
- SDS
Last updated:2023-05-04 17:34:41
Melting point | 149.5°C |
---|---|
Boiling point | 565.2±60.0 °C(Predicted) |
Density | 1.3150 (rough estimate) |
refractive index | 1.6100 (estimate) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 9.26±0.60(Predicted) |
color | White to Pale Beige |
Stability | Hygroscopic |
FDA UNII | X1NS9SNS92 |
ATC code | C03BA05 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08,GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H373-H315-H335-H319 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P260-P314-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
Toxicity | LD50 oral in rabbit: > 3gm/kg |
mefruside price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | M205150 | Mefruside | 7195-27-9 | 5mg | $260 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0011858 | MEFRUSIDE 95.00% | 7195-27-9 | 1MG | $329.7 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0011858 | MEFRUSIDE 95.00% | 7195-27-9 | 5MG | $502.29 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 59614 | Mefruside | 7195-27-9 | 1mg | $650 | 2021-12-16 | Buy |
mefruside Chemical Properties,Uses,Production
Originator
Baycaron,Bayer,W. Germany,1967
Uses
Mefruside is a diuretic used for the treatment of edema and hypertension.
Definition
ChEBI: Mefruside is an organic molecular entity.
Manufacturing Process
By hydrogenation of α-methyl-α-cyanotetrahydrofuran with Raney nickel as catalyst, α-methyl-α-tetrahydrofurfuryl amine is obtained (BP 48°C/12 mm Hg) which is alkylated by dimethyl sulfate to give α-methyl-αtetrahydrofurfurylmethylamine (BP 70°C/40 mm Hg). The amine is then reacted with 4-chloro-3-sulfamyl benzene sulfochloride in the presence of an acid acceptor. The mixture is stirred overnight, the solvent (acetone or pyridine) is driven off under vacuum and the residue is recrystallized from alcohol.
Therapeutic Function
Diuretic
mefruside Preparation Products And Raw materials
Global( 28)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3791 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55672 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 15353716720 | 1052@dideu.com | China | 10009 | 58 |
View Lastest Price from mefruside manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-20 | mefruside
7195-27-9
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | ||
2021-07-09 | mefruside USP/EP/BP
7195-27-9
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
- mefruside
7195-27-9
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
- mefruside USP/EP/BP
7195-27-9
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
7195-27-9(mefruside)Related Search:
1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]- (9CI)
4-Chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)-m-benzenedisulfonamide
B 1500
BAY 1500
Baycaron
FBA 1500
FDA 1902
m-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)- (7CI, 8CI)
N-(4'-Chloro-3'-sulfamoylbenzenesulfonyl)-N-methyl-2-aminomethyl-2-methyltetrahydrofuran
N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine
mefruside
4-Chloro-N-methyl-N-(tetrahydro-2-methylfuran-2-yl)-1,3-benzenedisulfonamide
Mefrusid
4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide
4-chloro-N1-methyl-N1-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide
4-chloro-N-methyl-N-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide
mefruside USP/EP/BP
1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]-
Valine Impurity 35
7195-27-9
C13H19ClN2O5S2