pecazine
- CAS No.
- 60-89-9
- Chemical Name:
- pecazine
- Synonyms
- Paxital;Pecatal;Lacumin;Mepazin;MEPAZINE;Pacazine;pecazine;Ai3-50131;Nothiazine;Einecs 200-490-8
- CBNumber:
- CB5876419
- Molecular Formula:
- C19H22N2S
- Molecular Weight:
- 310.46
- MDL Number:
- MOL File:
- 60-89-9.mol
| Melting point | 80°C |
|---|---|
| Boiling point | bp4 230-235° |
| Density | 1.1252 (rough estimate) |
| refractive index | 1.6270 (estimate) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO : 130 mg/mL (418.73 mM; Need ultrasonic) |
| Water Solubility | 5.588mg/L(24 ºC) |
| FDA UNII | PH34873A38 |
pecazine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P218285 | Pecazine | 60-89-9 | 100mg | $165 | 2021-12-16 | Buy |
| Usbiological | 287263 | Pecazine | 60-89-9 | 10g | $319 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0012197 | PECAZINE 95.00% | 60-89-9 | 5MG | $503.06 | 2021-12-16 | Buy |
| Matrix Scientific | 176622 | 10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine | 60-89-9 | 100mg | $990 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 71902 | Pecazine | 60-89-9 | 1g | $2200 | 2021-12-16 | Buy |
pecazine Chemical Properties,Uses,Production
Originator
Pacatal,Warner Lambert,US,1957
Uses
Pecazine Hydrochloride acts as an anti-HIV agent in the form of C-C chemokine inhibitors.
Definition
ChEBI: Pecazine is a member of phenothiazines.
Manufacturing Process
A 500 cc flask equipped with a mechanical stirrer, reflux condenser and a soda-lime tube was filled with 230 cc of absolute xylene, 27.5 g of 1-methyl3-bromomethylpiperidine, 53.3 g of phenothiazine and 14.2 g of finely powdered sodium amide, and the solution was heated under reflux for 6 hours. After cooling water was added and the batch was extracted with ether. As the hydrochloric acid salt of the obtained phenothiazine derivative is difficultly soluble in water, the further processing was carried out by way of the acetate. The etheric solution was extracted several times in a separating funnel with dilute acetic acid. The combined aqueous extracts were basified, extracted with ether, dried with potassium carbonate and, after removal of the ether, distilled in vacuo.
Yield = 64%; boiling point 230°C to 235°C at 4 mm; melting point of
hydrochloride is 180°C to 181°C.
Therapeutic Function
Tranquilizer
pecazine Preparation Products And Raw materials
pecazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| VladaChem GmbH | +49-7246-3082843 | info@vladachem.de | Germany | 1860 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9116 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9374 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Heze Development Zone chuangli Chemical Co., Ltd. | +86-530-529 6766，+86-15666160102 15666160102 | info@chuangli-chem.com | China | 877 | 55 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |