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Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate structure

CAS No.: 85267-60-3

Chemical Name:: Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

Synonyms: 3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine;Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

CBNumber:: CB59007160

Molecular Formula:: C18H24N2O7Si

Molecular Weight:: 408.48

MDL Number:

MOL File:: 85267-60-3.mol

Last updated:2023-04-27 16:27:43

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Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Properties

Density	1.27±0.1 g/cm3(Predicted)
pka	8.83±0.10(Predicted)

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Chemical Properties,Uses,Production

Uses

3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

1.Add DMAP (0.16 mmol, 20 mg) to a stirred suspension of 2'-deoxyuridine (1 mmol, 228 mg) in acetic anhydride (7.5 mL).2.Observe the reaction mixture become homogenous for 6 hours.3.Remove the volatiles in vacuum.4.Purify the residue by flash chromatography on silica gel eluted with EA/cyclohexane (4:1 → 19:1, v/v) to obtain 3',5'-di-O-acetyl-2'-deoxyuridine.

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate synthesis

Synthesis of Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate from 3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE and Trimethylsilylacetylene

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Preparation Products And Raw materials

Raw materials

3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE Trimethylsilylacetylene

Preparation Products

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NewCan Biotech Limited	+86-0571-86912261 +86-15658003402	sales@newcanbio.com	China	329	58
Zhengzhou Chemprize Biotech Co., Ltd.	15981919713	sales@chemprize.com	China	408	58

Supplier	Advantage
NewCan Biotech Limited	58
Zhengzhou Chemprize Biotech Co., Ltd.	58

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate 3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine 85267-60-3 C18H24N2O7Si