medibazine
- CAS No.
- 53-31-6
- Chemical Name:
- medibazine
- Synonyms
- S-4105;medibazine;1-(Diphenylmethyl)-4-(1,3-benzodioxol-5-ylmethyl)piperazine;1-(1,3-Benzodioxol-5-ylmethyl)-4-(diphenylmethyl)piperazine;Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-4-(diphenylmethyl)-
- CBNumber:
- CB5935121
- Molecular Formula:
- C25H26N2O2
- Molecular Weight:
- 386.49
- MDL Number:
- MFCD00868250
- MOL File:
- 53-31-6.mol
| FDA UNII | 7NFK89B690 |
|---|
medibazine Chemical Properties,Uses,Production
Originator
Vialibran,Servier
Uses
Medibazine is studied as a distinguishing compound with antibacterial activity by artificial neural networks.
Definition
ChEBI: Medibazine is a diarylmethane.
Manufacturing Process
To a solution of 32 g piperonyl piperazine in 100 ml anhydrous toluene, 10 g sodium carbonate are added and 35.2 g benzhydryl chloride are added dropwise. The mixture is then heated to reflux for 7 hours with vigorous agitation. Then the mixture is cooled, the salt that has formed is filtered out and 100 ml water is added. The organic layer is extracted with several batches of 10% methane sulfonic acid. The acid extracts are combined and washed with ether then alkalized with sodium carbonate. The mixture is extracted with several batches of chloroform and the combined chloroform solutions are washed several times with water. After drying and solvent evaporation, the crude base of 1-diphenylmethyl-4-piperonyl-piperazineis isolated and the hydrochloride thereof is formed in acetone. After recrystallization 22.5 g of the dihydrochloride are finally obtained. M.P.: 228°C, from methanol.
Therapeutic Function
Coronary vasodilator
medibazine Preparation Products And Raw materials
medibazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10008 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 58 |