ChemicalBook >> CAS DataBase List >>GW 3965 HYDROCHLORIDE
GW 3965 HYDROCHLORIDE
- CAS No.
- 405911-17-3
- Chemical Name:
- GW 3965 HYDROCHLORIDE
- Synonyms
- CS-742;GW3965 HCl;GW3965 HCl Salt;W 3965 HYDROCHLORIDE;GW3965 hydrochloride, >=98%;GW-3965 hydrochloride GW3965;GW 3965 HYDROCHLORIDE; GW-3965 HYDROCHLORIDE;;3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…;2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylet...;3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride
- CBNumber:
- CB5972490
- Molecular Formula:
- C33H31ClF3NO3.HCl
- Molecular Weight:
- 0
- MDL Number:
- MFCD08276920
- MOL File:
- 405911-17-3.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318-H413 | |||||||||
| Precautionary statements | P264-P270-P273-P280-P301+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
GW 3965 HYDROCHLORIDE price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G6295 | GW3965 hydrochloride ≥98% (HPLC), powder | 405911-17-3 | 5mg | $206 | 2024-03-01 | Buy |
| Sigma-Aldrich | G6295 | GW3965 hydrochloride ≥98% (HPLC), powder | 405911-17-3 | 25mg | $702 | 2024-03-01 | Buy |
| Cayman Chemical | 10054 | GW 3965 (hydrochloride) ≥98% | 405911-17-3 | 1mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 10054 | GW 3965 (hydrochloride) ≥98% | 405911-17-3 | 5mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 10054 | GW 3965 (hydrochloride) ≥98% | 405911-17-3 | 10mg | $175 | 2024-03-01 | Buy |
GW 3965 HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.
Biochem/physiol Actions
GW3965 is a liver X receptor full agonist on hLXRα and hLXRβ. GW3965 has an EC50 = 125 nM in a cell-free ligand-sensing assay of LXRα and profiles as a full agonist on hLXRα and hLXRβ in cell-based assays with EC50 = 190 nM and 30 nM, respectively. It is orally active in mice. When screened against a panel of nuclear receptors, it cross-reacted with only the pregnane X receptor (PXR). The literature agonist, T0901317 (Tularik), had an EC50 = 60 nM and 85 nM in the cell-free and cell-based assays, respectively.
storage
Desiccate at RT
GW 3965 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 120)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | sales@allfluoro.com | China | 5791 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6711 | 58 |
| Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | chem1022@hengdian-group.com | China | 1469 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
View Lastest Price from GW 3965 HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-09-08 | GW3965 HCl
405911-17-3
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2020-01-09 | GW 3965 HYDROCHLORIDE
405911-17-3
|
US $1.00 / KG | 1KG | 85.0-99.8% | 20tons | Career Henan Chemical Co |
-
- GW3965 HCl
405911-17-3
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- GW 3965 HYDROCHLORIDE
405911-17-3
- US $1.00 / KG
- 85.0-99.8%
- Career Henan Chemical Co
405911-17-3(GW 3965 HYDROCHLORIDE)Related Search:
3-[3-[n-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…
GW3965 HCl
2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride
GW3965 hydrochloride, >=98%
Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride
GW3965 HCl Salt
3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride
CS-742
GW 3965 HYDROCHLORIDE; GW-3965 HYDROCHLORIDE;
3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride
2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylet...
GW-3965 hydrochloride GW3965
Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride (1:1)
3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-Benzeneacetic acid hydrochloride (1:1)
W 3965 HYDROCHLORIDE
405911-17-3
C33H31F3ClNO3HCl
Inhibitors