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ETIROXATE

CAS No.
17365-01-4
Chemical Name:
ETIROXATE
Synonyms
CG-63;CG-635;ETIROXATE;DL-a-Methyl-thyroxine Ethyl Ester;DL-α-Methyl-thyroxine Ethyl Ester;Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester;(±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester
CBNumber:
CB5985045
Molecular Formula:
C18H17I4NO4
Molecular Weight:
818.935
MDL Number:
MFCD00865750
MOL File:
17365-01-4.mol
Last updated:2023-05-04 17:34:34

ETIROXATE Properties

Melting point 149-1510C
Boiling point 563.7±50.0 °C(Predicted)
Density 2.321±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO, Methanol
form Solid
pka 6.89±0.25(Predicted)
color Tan
FDA UNII 0S3LDN5P7H

ETIROXATE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E932980 Etiroxate 17365-01-4 5mg $90 2021-12-16 Buy
TRC E932980 Etiroxate 17365-01-4 10mg $110 2021-12-16 Buy
American Custom Chemicals Corporation API0000557 ETIROXATE 95.00% 17365-01-4 5MG $311.3 2021-12-16 Buy
American Custom Chemicals Corporation API0000557 ETIROXATE 95.00% 17365-01-4 10MG $704.55 2021-12-16 Buy
Medical Isotopes, Inc. 10176 Etiroxate 17365-01-4 10mg $860 2021-12-16 Buy
Product number Packaging Price Buy
E932980 5mg $90 Buy
E932980 10mg $110 Buy
API0000557 5MG $311.3 Buy
API0000557 10MG $704.55 Buy
10176 10mg $860 Buy

ETIROXATE Chemical Properties,Uses,Production

Chemical Properties

Tan Solid

Originator

Skleronorm,Gruenenthal,W. Germany,1977

Uses

Derivative of thyroxine. Antilipemic.

Definition

ChEBI: Etiroxate is an aromatic ether.

Manufacturing Process

7.91 g of α-methyl thyroxine are suspended in 150 cc of ethanol. While heating, the solution is saturated with dry hydrogen chloride. Thereafter, the solvent is distilled off at reduced pressure. The residue is dissolved in a mixture of ethanol and water (1:1). Adding a 5% solution of sodium hydrogen carbonate in water, the ethyl ester of α-methyl thyroxine precipitates; melting point: 156°C to 157°C after recrystallization from ethanol. The yield is 6.05 g, i.e., 74% of the theoretical yield.

Therapeutic Function

Antihyperlipoproteinemic

ETIROXATE Preparation Products And Raw materials

Raw materials

Preparation Products

ETIROXATE Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55477 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 2329783215@qq.com China 12664 58
CG-63 DL-a-Methyl-thyroxine Ethyl Ester O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester (±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester CG-635 DL-α-Methyl-thyroxine Ethyl Ester O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester ETIROXATE Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester 17365-01-4 C18H17I4NO4 Intermediates & Fine Chemicals Pharmaceuticals