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Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate

CAS No.
1035490-58-4
Chemical Name:
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate
Synonyms
(S)-2-(Boc-amino)-2-(3-fluorophenyl)ethanol;tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate;tert-butyl N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]carbamate;(S)-1-(3-fluoro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester;Carbamic acid, N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
CBNumber:
CB610468902
Molecular Formula:
C13H18FNO3
Molecular Weight:
255.29
MDL Number:
MOL File:
1035490-58-4.mol
Last updated:2023-09-27 17:18:56

Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Properties

Boiling point 381.4±37.0 °C(Predicted)
Density 1.162±0.06 g/cm3(Predicted)
pka 11.38±0.46(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Chemical Properties,Uses,Production

Physical properties

A white crystal,melting point:106.5 - 107.9

Uses

Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate is a useful research chemical for a range of applications.

Preparation

Amino alcohol hydrochloride (192.22 mmol) and di-f-butyl dicarbonate (262.63 mmol, 1.37 eq) were suspended in f-BuOH (250 mL, 6.25 volumes) and then treated with aqueous 2 N NaOH (120 mL, 240 mmol). The contents were warmed to 75 °C (immediate effervescence was observed) for 4 h. The internal temp was then reduced to 50 °C, and the contents were added to water (2 L) with vigorous stirring. Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate was obtained after purification.
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate

24424-99-5
1240480-36-7
1035490-58-4
Synthesis of Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate from Di-tert-butyl dicarbonate and (2S)-2-AMINO-2-(3-FLUOROPHENYL)ETHAN-1-OL HCL

Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Preparation Products And Raw materials

Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Suppliers

Global( 11)Suppliers
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Tianjin Xinghan Biotechnology Co., Ltd
+8618698089028 1725517238@qq.com China 2479 58
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Amatek Scientific Co. Ltd. 0512-56316828 info@amateksci.com China 28821 58
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Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 61720 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39668 58
Tianjin Xinghan Biotechnology Co., Ltd 13230698506 18698089028 1725517238@qq.com China 5009 58
Ningbo Chemrio Chemtech Co,.Ltd. 0574-27891269 18667892864 frank.xiaodong@chemriotech.com China 3489 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
Suzhou Chirui Zhihe Biotechnology Co., Ltd. 0512-13626191578 13626191578 1286165382@qq.com China 407 58
Carbamic acid, N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester (S)-1-(3-fluoro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester tert-butyl N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]carbamate tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate (S)-2-(Boc-amino)-2-(3-fluorophenyl)ethanol 1035490-58-4