Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate
- CAS No.
- 1035490-58-4
- Chemical Name:
- Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate
- Synonyms
- (S)-2-(Boc-amino)-2-(3-fluorophenyl)ethanol;tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate;tert-butyl N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]carbamate;(S)-1-(3-fluoro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester;Carbamic acid, N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB610468902
- Molecular Formula:
- C13H18FNO3
- Molecular Weight:
- 255.29
- MDL Number:
- MOL File:
- 1035490-58-4.mol
| Boiling point | 381.4±37.0 °C(Predicted) |
|---|---|
| Density | 1.162±0.06 g/cm3(Predicted) |
| pka | 11.38±0.46(Predicted) |
| InChI | InChI=1S/C13H18FNO3/c1-13(2,3)18-12(17)15-11(8-16)9-5-4-6-10(14)7-9/h4-7,11,16H,8H2,1-3H3,(H,15,17)/t11-/m1/s1 |
| InChIKey | PXLWDYOUWTYABH-LLVKDONJSA-N |
| SMILES | C(OC(C)(C)C)(=O)N[C@@H](C1=CC=CC(F)=C1)CO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Chemical Properties,Uses,Production
Physical properties
A white crystal,melting point:106.5 - 107.9
Uses
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate is a useful research chemical for a range of applications.
Preparation
Amino alcohol hydrochloride (192.22 mmol) and di-f-butyl dicarbonate (262.63 mmol, 1.37 eq) were suspended in f-BuOH (250 mL, 6.25 volumes) and then treated with aqueous 2 N NaOH (120 mL, 240 mmol). The contents were warmed to 75 °C (immediate effervescence was observed) for 4 h. The internal temp was then reduced to 50 °C, and the contents were added to water (2 L) with vigorous stirring. Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate was obtained after purification.
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Xinghan Biotechnology Co., Ltd | +8618698089028 | 1725517238@qq.com | China | 2479 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39002 | 58 |
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| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28787 | 58 |
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| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39665 | 58 |
| Tianjin Xinghan Biotechnology Co., Ltd | 13230698506 18698089028 | 1725517238@qq.com | China | 5009 | 58 |
| Ningbo Chemrio Chemtech Co,.Ltd. | 0574-27891269 18667892864 | frank.xiaodong@chemriotech.com | China | 3818 | 58 |
