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ChemicalBook >> CAS DataBase List >>Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)-

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)-

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- Structure
Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- structure
CAS No.
2654741-64-5
Chemical Name:
Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)-
Synonyms
SOS1-IN-11;SOS1 inhibitor;inhibit,Inhibitor,Ras,SOS1IN11,SOS1 IN 11;Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)-
CBNumber:
CB610967566
Molecular Formula:
C22H24F3N5O
Molecular Weight:
431.45
MDL Number:
MOL File:
2654741-64-5.mol
Last updated:2024-07-02 08:55:12
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Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- Properties

Boiling point 596.8±50.0 °C(Predicted)
Density 1.307±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (231.78 mM; Need ultrasonic)
pka 7.92±0.30(Predicted)
form Solid
color Light yellow to yellow

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- Chemical Properties,Uses,Production

Biological Activity

SOS1-IN-11 is a potent SOS1 inhibitor with an IC50 value of 30 nM.

References

[1]. Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429 A1.

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- Suppliers

Global( 5)Suppliers
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32836 60
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5586 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11976 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29978 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
https://hanhongsci.com/ 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- Spectrum

Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)-(2654741-64-5)1HNMR
Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- SOS1 inhibitor SOS1-IN-11 inhibit,Inhibitor,Ras,SOS1IN11,SOS1 IN 11 2654741-64-5