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5-hydroxy-l-tryptophan

CAS No.
314062-44-7
Chemical Name:
5-hydroxy-l-tryptophan
Synonyms
5-HYDROXY-L-TRYPTOPHAN;5-HTP;L-5-HTP;L-HTP-OH;H-TRP(5-OH)-OH;5-HYDROXY-TRP-OH;H-5-HYDROXY-TRP-OH;5-HYDROXY-L-TRP-OH;C5-HYDROXY-L-TRYPTOPHAN;L-5-HYDROXYTRYPTOPHAN HYDRATE
CBNumber:
CB6110024
Molecular Formula:
C11H12N2O3
Molecular Weight:
220.22
MDL Number:
MFCD00064341
MOL File:
314062-44-7.mol
MSDS File:
SDS
Last updated:2024-03-28 13:39:29

5-hydroxy-l-tryptophan Properties

Melting point 270 °C (dec.)(lit.)
Density 0.902 g/mL at 25 °C(lit.)
refractive index n20/D 1.4850(lit.)
Flash point 175 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility H2O: 10 mg/mL
form solid
color white
InChI InChI=1/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/s3
InChIKey LDCYZAJDBXYCGN-DJEYLCQNNA-N
SMILES C12C=C(C=CC=1NC=C2C[C@H](N)C(=O)O)O |&1:10,r|
CAS DataBase Reference 314062-44-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P501-P270-P264-P301+P310+P330-P405
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  YN7110000
3-10

5-hydroxy-l-tryptophan price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation CCH0000443 L-5-HYDROXYTRYPTOPHAN HYDRATE 95.00% 314062-44-7 250MG $567.93 2021-12-16 Buy
American Custom Chemicals Corporation CCH0000443 L-5-HYDROXYTRYPTOPHAN HYDRATE 95.00% 314062-44-7 1G $643.37 2021-12-16 Buy
American Custom Chemicals Corporation CCH0000443 L-5-HYDROXYTRYPTOPHAN HYDRATE 95.00% 314062-44-7 5G $889.68 2021-12-16 Buy
Chemenu CM192656 (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacidhydrate 95% 314062-44-7 100g $466 2021-12-16 Buy
Crysdot CD21008743 (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacidhydrate 95+% 314062-44-7 100g $493 2021-12-16 Buy
Product number Packaging Price Buy
CCH0000443 250MG $567.93 Buy
CCH0000443 1G $643.37 Buy
CCH0000443 5G $889.68 Buy
CM192656 100g $466 Buy
CD21008743 100g $493 Buy

5-hydroxy-l-tryptophan Chemical Properties,Uses,Production

Description

5-hydroxy-l-tryptophan (5-HTP) is a chemical byproduct of the protein building block L-tryptophan. It is produced commercially from the seeds of an African plant known as Griffonia simplicifolia. In vivo, it is produced from tryptophan by tryptophan hydroxylase (TPH), and its decarboxylation yields serotonin (5-hydroxytryptamine, 5-HT), a monoamine neurotransmitter involved in the modulation of mood, cognition, reward, learning, memory, sleep, and numerous other physiological processes. 5-HTP is both a drug and a natural component of some dietary supplements, and occurrence in both synthetic tryptophan and 5-HTP of toxic impurities has caused eosinophilia myalgia syndrome cases[1].

Uses

5-hydroxy-l-tryptophan is metabolized into serotonin and is thought to alleviate depression by enhancing serotonin neurotransmission. It is also used to treat fibromyalgia, insomnia, binge-eating, attention deficit disorder, and chronic headaches.

References

[1] Maffei, Massimo E. "5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology." International Journal of Molecular Sciences 22.1(2021):181.

5-hydroxy-l-tryptophan Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
Hong Kong Excellence Biotechnology Co., Ltd.
+86-86-18838029171 +8618126314766 ada@sh-teruiop.com China 892 58
Sigma Audley
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Shanghai Aosiris new Material Technology Co., LTD
+8615139564871 wrjmoon2000@163.com China 354 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 224 58
Capot Chemical Co.,Ltd.
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Jinan Jianfeng Chemical Co., Ltd
0531-88110457; +8615562555968 info@pharmachemm.com China 246 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58

View Lastest Price from 5-hydroxy-l-tryptophan manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-HYDROXY-L-TRYPTOPHAN pictures 2024-04-18 5-HYDROXY-L-TRYPTOPHAN
314062-44-7
US $1.00 / g 1g 99.9+% 20T Jinan Jianfeng Chemical Co., Ltd
5-hydroxy-l-tryptophan pictures 2024-04-12 5-hydroxy-l-tryptophan
314062-44-7
US $3.00-1.00 / kg 1kg 99.9% 10 tons Shanghai Aosiris new Material Technology Co., LTD
5-hydroxy-l-tryptophan pictures 2024-04-11 5-hydroxy-l-tryptophan
314062-44-7
US $0.00 / kg 1kg >98% 1000 kg BINBO BIOLOGICAL CO.,LTD
(S)-2-AMino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid hydrate 5-HYDROXY-TRP-OH 5-HYDROXY-L-TRP-OH 5-HTP (S)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)-PROPIONIC ACID C5-HYDROXY-L-TRYPTOPHAN H-TRP(5-OH)-OH H-5-HYDROXY-TRP-OH L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID L-5-HTP L-5-HYDROXYTRYPTOPHAN HYDRATE 2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID L-HTP-OH -2-Amino-3-(5-hydroxy-1H-indol-3-yl) Griffonia Seed Extract(5-HTP) (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacid,hydrate 5-HYDROXY-L-TRYPTOPHAN USP/EP/BP L-5HTP(5-HYDROXY-L-TRYPTOPHAN) 5-HYDROXY-L-TRYPTOPHAN 314062-44-7 Unnatural Amino Acid Derivatives Specialty Synthesis Peptide Synthesis Tryptophans Indoles Tryptophan Derivatives