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Theaflavin

Theaflavin structure

CAS No.: 4670-05-7

Chemical Name:: Theaflavin

Synonyms: Theaflavins;THEAFLAVINE;6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one;THEAFLAVIN;Theaflavin 1;6-trihydroxy-;THEAFLAVIN USP/EP/BP;hot selling Theaflavine;Theaflavin, froM green tea;Theaflavin, 98%, from green tea

CBNumber:: CB6110367

Molecular Formula:: C29H24O12

Molecular Weight:: 564.49

MDL Number:: MFCD03427500

MOL File:: 4670-05-7.mol

Last updated:2023-05-25 18:01:14

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Theaflavin Properties

Melting point	237-240 °C (decomp)(Solv: water (7732-18-5))
Boiling point	1079.6±65.0 °C(Predicted)
Density	1.777±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	6.65±0.20(Predicted)
color	Red to Very Dark Red
LogP	1.165 (est)
NCI Dictionary of Cancer Terms	theaflavin
FDA UNII	1IA46M0D13

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
Safety Statements	24/25
WGK Germany	3
HS Code	29329990

Theaflavin price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHL83341	Theaflavin phyproof? Reference Substance	4670-05-7	10mg	$514	2024-03-01	Buy
Sigma-Aldrich	55016	Theaflavin analytical standard	4670-05-7	1mg	$757	2024-03-01	Buy
Cayman Chemical	25129	Theaflavin ≥98%	4670-05-7	1mg	$36	2024-03-01	Buy
Cayman Chemical	25129	Theaflavin ≥98%	4670-05-7	5mg	$130	2024-03-01	Buy
Cayman Chemical	25129	Theaflavin ≥98%	4670-05-7	10mg	$239	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHL83341	10mg	$514	Buy
55016	1mg	$757	Buy
25129	1mg	$36	Buy
25129	5mg	$130	Buy
25129	10mg	$239	Buy

Theaflavin Chemical Properties,Uses,Production

Description

Theaflavins are a group of polyphenol pigments found in both black and oolong teas. They are obtained by the oxidation and dimerization of green tea catechins during the manufacture of black tea and oolong tea. Theaflavins contribute to the characteristic bright orange-red color of black tea. Theaflavins include theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate and theaflavin-3,3'-digallate.
Theaflavins are used to manage cholesterol and used to support the heart and digestive system. They could be used as protective agents against cardiovascular disease and cancer. It is also believed that they have a wide range of other pharmaceutical benefits, including antihypertensive, antioxidative and hypolipidemic activities. It is suggested that theaflavins have a potential to be developed as a safe and affordable topical microbicide for preventing sexual transmission of HIV.

Chemical Properties

red to brown powder

Uses

Theaflavin is a polyphenolic compound found in black tea. Theaflavin derivatives show anti-HIV-1 activity by targeting gp41. Theaflavin is a potent inhibitor of amyloid-β (Aβ) and α-synuclein (αS) fibrillogenesis. Theaflavin also shows potent anti-tumor and and antoxidant activities.

Definition

ChEBI: Theaflavin is a biflavonoid that is 3,4,5-trihydroxybenzocyclohepten-6-one which is substituted at positions 1 and 8 by (2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl groups. It is the main red pigment in black tea. It has a role as an antioxidant, a chelator, a plant metabolite, a radiation protective agent and an antibacterial agent. It is a polyphenol and a biflavonoid.

benefits

Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antineoplastic, antioxidant, anticancer, anti-inflammatory, cholesterol lowering and antiviral properties.

Biological Activity

Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

References

[1] Lai Kwok Leung, Yalun Su, Ruoyun Chen, Zesheng Zhang, Yu Huang, Zhen-Yu Chen (2001) Theaflavins in Black Tea and Catechins in Green Tea Are Equally Effective, J. Nutr., 131, 2248-2251
[2] Yang J, Li L, Tan S, Jin H, Qiu J, Mao Q, Li R, Xia C, Jiang ZH, Jiang S, Liu S (2012) A Natural Theaflavins Preparation Inhibits HIV-1 Infection by Targeting the Entry Step: Potential Applications for Preventing HIV-1 Infection, Fitoterapia, 83, 348-355
[3] http://www.xtend-life.com/information/ingredients/theaflavins

Theaflavin Preparation Products And Raw materials

Raw materials

Preparation Products

Theaflavin Suppliers

Global( 176)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253	jancyzheng@gcgreenpure.com	China	952	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu Greenpure Biopharma CO.,Ltd	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Shaanxi Pioneer Biotech Co., Ltd .	58
HubeiwidelychemicaltechnologyCo.,Ltd	58
BOC Sciences	58

View Lastest Price from Theaflavin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-09	THEAFLAVIN 4670-05-7	US $0.00 / MG	10MG	≥98% HPLC	100kg	Changsha Staherb Natural Ingredients Co., Ltd.
2023-02-24	Theaflavin 4670-05-7	US $0.00 / mg	20mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
2021-07-13	THEAFLAVIN 4670-05-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

THEAFLAVIN
4670-05-7
US $0.00 / MG
≥98% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

Theaflavin
4670-05-7
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

THEAFLAVIN
4670-05-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4670-05-7(Theaflavin)Related Search:

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THEAFLAVIN 3-GALLATE THEAFLAVIN (BLACK TEA) STANDARDS KIT

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THEAFLAVIN 1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-5h-benzocyclohepten-5-one 5h-benzocyclohepten-5-one,1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-3, 6-trihydroxy- 3,4,6-Trihydroxy-1,8-bis(3,4-dihydro-3α,5,7-trihydroxy-2H-1-benzopyran-2α-yl)-5H-benzocycloheptene-5-one 3,4,6-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxychroman-2-yl]-5H-benzocycloheptene-5-one 3,4,6-Trihydroxy-1,8-bis[[(2R)-3,4-dihydro-3α,5,7-trihydroxy-2H-1-benzopyran]-2α-yl]-5H-benzocyclohepten-5-one 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-6-one 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxychroman-2-yl]benzocyclohepten-6-one [2R-[2α(2R*,3R*),3α]]-1,8-Bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one 1,8-Bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5H-benzocyclohepten-5-one 3,4,6-Trihydroxy-1,8-bis(3α,5,7-trihydroxy-2α-chroManyl)-5H-benzocyclohepten-5-one Theaflavin 1 Theaflavin, froM green tea 5H-Benzocyclohepten-5-one,1,8-bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy- Theaflavin, 98%, from green tea 3,4,6-Trihydroxy-1,8-bis((2R,3R)-3,5,7-trihydroxychroman-2-yl)-5H-benzo[7]annulen-5-one hot selling Theaflavine THEAFLAVIN USP/EP/BP 5H-Benzocyclohepten-5-one, 1,8-bis[(2R,3R)-3,4-dihydro-3,5,7... TheaflavinQ: What is Theaflavin Q: What is the CAS Number of Theaflavin Q: What is the storage condition of Theaflavin Q: What are the applications of Theaflavin THEAFLAVINE Theaflavins 6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one 4670-05-7 4670-''5-7 C29H24O12 C29H24O9 Miscellaneous Natural Products