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KAHWEOL

KAHWEOL structure

CAS No.: 6894-43-5

Chemical Name:: KAHWEOL

Synonyms: KAHWEOL;KAHWEOL USP/EP/BP;Kahweol DISCONTINUED, unstable;(3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-;[3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol

CBNumber:: CB6117982

Molecular Formula:: C20H26O3

Molecular Weight:: 314.42

MDL Number:: MFCD00171665

MOL File:: 6894-43-5.mol

Last updated:2023-05-25 18:01:14

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KAHWEOL Properties

Melting point	88-90℃
Boiling point	476.6±45.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM) DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM) Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM)
pka	14.43±0.40(Predicted)
form	White to off-white solid.
LogP	3.380 (est)
FDA UNII	KX95B6688Y

KAHWEOL price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	14015	Kahweol ≥98%	6894-43-5	5mg	$86	2024-03-01	Buy
Cayman Chemical	14015	Kahweol ≥98%	6894-43-5	10mg	$135	2024-03-01	Buy
Cayman Chemical	14015	Kahweol ≥98%	6894-43-5	25mg	$315	2024-03-01	Buy
Biorbyt Ltd	orb594400	Kahweol	6894-43-5	20mg	$391	2021-12-16	Buy
ChemScene	CS-0032794	Kahweol ≥98.0%	6894-43-5	20mg	$429	2021-12-16	Buy

Product number	Packaging	Price	Buy
14015	5mg	$86	Buy
14015	10mg	$135	Buy
14015	25mg	$315	Buy
orb594400	20mg	$391	Buy
CS-0032794	20mg	$429	Buy

KAHWEOL Chemical Properties,Uses,Production

Uses

Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation.

Definition

ChEBI: Kahweol is a diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. It has a role as an angiogenesis inhibitor, an apoptosis inducer, an antioxidant, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a diterpenoid, a member of furans, an organic heteropentacyclic compound, a tertiary alcohol and a primary alcohol.

KAHWEOL Preparation Products And Raw materials

Raw materials

Preparation Products

KAHWEOL Suppliers

Global( 97)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29322	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Xi'an Kono chem co., Ltd.,	58
Career Henan Chemica Co	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
J & K SCIENTIFIC LTD.	76

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KAHWEOL (3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol [3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)- KAHWEOL USP/EP/BP Kahweol DISCONTINUED, unstable 6894-43-5 6984-43-5 Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals