PIPERIDOLATE HYDROCHLORIDE
- CAS No.
- 129-77-1
- Chemical Name:
- PIPERIDOLATE HYDROCHLORIDE
- Synonyms
- Crapinon;NSC 4349;Dihyprylone;Piperidolate HCl;dactilhydrochloride;PIPERIDOLATE HYDROCHLORIDE;3,3-Diethyl-2,4-piperidinedione;Piperidolate Hydrochloride (200 mg);Piperidolate Hydrochloride (1543006);n-ethyl-3-piperidyldiphenylacetatehydrochloride
- CBNumber:
- CB6126948
- Molecular Formula:
- C21H26ClNO2
- Molecular Weight:
- 359.89
- MDL Number:
- MFCD00057377
- MOL File:
- 129-77-1.mol
- MSDS File:
- SDS
| Melting point | 195-196° |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | 57UA660ILV |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H332-H312 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501 |
PIPERIDOLATE HYDROCHLORIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-4446 | Piperidolatehydrochloride 99.94% | 129-77-1 | 100mg | $228 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0012877 | PIPERIDOLATE HYDROCHLORIDE 98.00% | 129-77-1 | 10MG | $280.35 | 2021-12-16 | Buy |
| ChemScene | CS-4446 | Piperidolatehydrochloride 99.94% | 129-77-1 | 200mg | $312 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0012877 | PIPERIDOLATE HYDROCHLORIDE 98.00% | 129-77-1 | 250G | $4548.39 | 2021-12-16 | Buy |
| Crysdot | CD31003974 | Piperidolatehydrochloride 98+% | 129-77-1 | 100mg | $132 | 2021-12-16 | Buy |
PIPERIDOLATE HYDROCHLORIDE Chemical Properties,Uses,Production
Originator
Dactil, Merrell National ,US ,1954
Uses
Piperidolate Hydrochloride acts as an anticholinergic agent. Also a potential inhibitor of human glutathione transferase P1-1.
Definition
ChEBI: Piperidolate hydrochloride is a diarylmethane.
Manufacturing Process
To obtain the free base, 34 g (0.256 mol) of N-ethyl-3-piperidinol and 20 g (0.22 mol) of diphenylacetyl chloride were mixed in 80 cc of isopropanol and the solution was refluxed for 2 hours. The isopropanol was evaporated in vacuo at 30 mm pressure, the residue was dissolved in 150 cc of water and the aqueous solution was extracted several times with ether. The aqueous solution was then neutralized with potassium carbonate and extracted withether. The ethereal solution was dried over anhydrous potassium carbonate and the ether removed by distillation. The product was then distilled at its boiling point 180° to 181°C at 0.13 mm of mercury whereby 14 g of a clear yellow, viscous liquid was obtained. The nitrogen content for C21H25NO2 was calculated as 4.33% and the nitrogen content found was 4.21%.
The starting material was produced by the reaction of furfural with ethylamine followed by hydrogenation to give N-ethyl-N-(2-tetrahydrofurfuryl)amine. Treatment of that material with hydrogen bromide in acetic acid gives N-ethyl3-piperidinol.
brand name
Dactil (Marion Merrell Dow).
Therapeutic Function
Spasmolytic
PIPERIDOLATE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19639 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
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