ACYCLOVIR-D4
- CAS No.
- 1185179-33-2
- Chemical Name:
- ACYCLOVIR-D4
- Synonyms
- Zyclir-d4;Zovirax-d4;Herpevir-d4;Gerpevir-d4;Cargosil-d4;ACYCLOVIR-D4;Acicloftal-d4;Acycloguanosine-d4;Acyclovir Impurity 18;Cytarabine Impurity 60
- CBNumber:
- CB6128250
- Molecular Formula:
- C8H7D4N5O3
- Molecular Weight:
- 229.23
- MDL Number:
- MFCD08063595
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
ACYCLOVIR-D4 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26272 | Acyclovir-d4 ≥99% deuterated forms (d0-d4) | 1185179-33-2 | 1mg | $224 | 2024-03-01 | Buy |
| Usbiological | A0858-52 | Acyclovir-d4 | 1185179-33-2 | 1mg | $460 | 2021-12-16 | Buy |
| TRC | A192402 | Acyclovir-d4 | 1185179-33-2 | 10mg | $1455 | 2021-12-16 | Buy |
| TRC | A192402 | Acyclovir-d4 | 1185179-33-2 | 1mg | $185 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006540 | ACYCLOVIR-D4 95.00% | 1185179-33-2 | 10MG | $1732.5 | 2021-12-16 | Buy |
ACYCLOVIR-D4 Chemical Properties,Uses,Production
Description
Acyclovir-d4 is intended for use as an internal standard for the quantification of acyclovir by GC- or LC-MS. Acyclovir is a guanosine analog that has antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1-63.1 μM). It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further DNA polymerase activity. Acyclovir (5 mg/kg) reduces viral titers in mice infected with the herpes simplex virus-1 (HSV-1) strain SC16.
Chemical Properties
Colourless Powder
Uses
Acyclovir-d4 can be intended for use as an internal standard for the quantification of Acyclovir by GC- or LC-mass spectrometry.
Uses
Acyclovir-d4can be ued as orally active acyclic labelled nucleoside with inhibitory activity towards several herpes viruses.
ACYCLOVIR-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@163.com | China | 284 | 58 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4515 | 55 |
| Clearsynth Canada Inc. | +1.415.685.4395 | enquiry@clearsynth.com | Canada | 912 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 02584622273; | kexin.zhou@haolvbiotech.com | China | 3021 | 58 |
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