Albuterol sulfate
- CAS No.
- 51022-70-9
- Chemical Name:
- Albuterol sulfate
- Synonyms
- SALBUTAMOL SULFATE;SALBUTAMOL SULPHATE;ALBUTEROL SULPHATE;Mozal;Volma;Cetsim;Respax;Loftan;Asmalin;Asmadil
- CBNumber:
- CB6129525
- Molecular Formula:
- C13H23NO7S
- Molecular Weight:
- 337.39
- MDL Number:
- MFCD00055200
- MOL File:
- 51022-70-9.mol
- MSDS File:
- SDS
| Melting point | 180 °C |
|---|---|
| Flash point | 250 °C |
| storage temp. | 2-8°C |
| solubility | 1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green |
| color | White |
| Water Solubility | Soluble in water and 1M sodium hydroxide (50 mg/ml). |
| Merck | 216 |
| BCS Class | 1 |
| InChI | InChI=1S/C13H21NO3.H2O4S/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4) |
| InChIKey | OVICLFZZVQVVFT-UHFFFAOYSA-N |
| SMILES | CC(C)(NCC(O)C1C=CC(O)=C(CO)C=1)C.S(O)(O)(=O)=O |
| CAS DataBase Reference | 51022-70-9(CAS DataBase Reference) |
| FDA UNII | 021SEF3731 |
| NCI Drug Dictionary | albuterol sulfate |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H351-H361fd | |||||||||
| Precautionary statements | P202-P261-P272-P280-P302+P352-P308+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 43-22 | |||||||||
| Safety Statements | 36/37-36 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | ZE4400000 | |||||||||
| HS Code | 29225090 | |||||||||
| NFPA 704 |
|
Albuterol sulfate price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR1053 | Albuterol sulfate Pharmaceutical Secondary Standard; Certified Reference Material | 51022-70-9 | 1g | $97.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP302 | Salbutamol sulfate British Pharmacopoeia (BP) Reference Standard | 51022-70-9 | 100MG | $255 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1012633 | Albuterol sulfate United States Pharmacopeia (USP) Reference Standard | 51022-70-9 | 200mg | $436 | 2024-03-01 | Buy |
| Alfa Aesar | A18544 | Salbutamol sulfate, 99% | 51022-70-9 | 1g | $46.65 | 2024-03-01 | Buy |
| Alfa Aesar | A18544 | Salbutamol sulfate, 99% | 51022-70-9 | 5g | $195 | 2024-03-01 | Buy |
Albuterol sulfate Chemical Properties,Uses,Production
Description
Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.
Chemical Properties
Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol.
Uses
Albuterol Sulfate belongs to a class of bronchodilator drugs called β2-adrenoceptor agonists. It is a prescription medicine used to treat symptoms of bronchospasm. Albuterol Sulfate may be used alone or with other medications.
Definition
ChEBI: Albuterol sulfate is an ethanolamine sulfate salt. It is functionally related to an albuterol.
brand name
Accuneb (Dey); Proair (IVAX); Proventil (Schering); Ventolin (GlaxoSmithKline); Volmax (Muro); Vospire (Odyssey).
General Description
Albuterol belongs to the class of medicines known as bronchodilators. It is also called a short-acting beta-agonist (SABA).
Biological Activity
Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.
Veterinary Drugs and Treatments
Albuterol is used principally in dogs and cats for its effects on bronchial smooth muscle to alleviate bronchospasm or cough. It is also used in horses as a bronchodilator.
storage
Store at RT
Mode of action
Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.
References
https://en.wikipedia.org/wiki/Salbutamol
https://www.drugbank.ca/drugs/DB01001
http://www.rxlist.com/albuterol-sulfate-drug/indications-dosage.htm
Albuterol sulfate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 874 | 58 |
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 | Ethan@dornechem.com | China | 294 | 58 |
| Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 | ada@sh-teruiop.com | China | 893 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | hanson@sdhanjiang.com | China | 1527 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
| Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 | wrjmoon2000@163.com | China | 352 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
View Lastest Price from Albuterol sulfate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-27 | Albuterol sulfate
51022-70-9
|
US $10.00 / ASSAYS | 1ASSAYS | 99% | 10 ton | Dorne Chemical Technology co. LTD | |
 |
2024-04-25 | Albuterol sulfate
51022-70-9
|
US $100.00 / kg | 1kg | 99.9% | 20tons | Hong Kong Excellence Biotechnology Co., Ltd. | |
 |
2024-04-18 | Albuterol sulfate
51022-70-9
|
US $3.00-1.00 / kg | 1kg | 99.9% | 10 tons | Shanghai Aosiris new Material Technology Co., LTD |
-
- Albuterol sulfate
51022-70-9
- US $10.00 / ASSAYS
- 99%
- Dorne Chemical Technology co. LTD
-
- Albuterol sulfate
51022-70-9
- US $100.00 / kg
- 99.9%
- Hong Kong Excellence Biotechnology Co., Ltd.
-
- Albuterol sulfate
51022-70-9
- US $3.00-1.00 / kg
- 99.9%
- Shanghai Aosiris new Material Technology Co., LTD