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Dextromethorphan hydrobromide monohydrate

Dextromethorphan hydrobromide monohydrate structure

CAS No.: 6700-34-1

Chemical Name:: Dextromethorphan hydrobromide monohydrate

Synonyms: Dextromethorphan HBr monohydrate;DextroMethorphan hydrobroMide hydrate;dextromethorphansigmareference*standard;Dextromethorphan Hydrobromide dextrorotation;(9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN HYDROBROMIDE, D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE MONOHYDRATE;DMHM;Dextromethorphan hyd;DEXTROMETHORPHAN HBr IP;Morphinan,3-methoxy-17-methyl-;Dextromethorphani Hydrobromidum

CBNumber:: CB6131946

Molecular Formula:: C18H28BrNO2

Molecular Weight:: 370.33

MDL Number:: MFCD02173901

MOL File:: 6700-34-1.mol

Last updated:2024-03-26 14:13:49

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Dextromethorphan hydrobromide monohydrate Properties

Melting point	116-119°C
alpha	[α]D25 +26～+30° (c=1.85, H2O)
Flash point	11 °C
storage temp.	Store at RT
solubility	Sparingly soluble in water, freely soluble in ethanol (96 per cent).
form	solid
color	White to Off-White
PH	pH (10g/l, 25℃) : 5.2～6.5
BRN	6453793
InChIKey	QYPSYPPSHXDFLV-UHFFFAOYSA-N
LogP	1.351 (est)
CAS DataBase Reference	6700-34-1(CAS DataBase Reference)
FDA UNII	9D2RTI9KYH

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS09

Signal word

Danger

Hazard statements

H301-H411

Precautionary statements

P264-P270-P273-P301+P310-P391-P405

Hazard Codes

F,T

Risk Statements

11-23/24/25-39/23/24/25

Safety Statements

7-16-36/37-45

WGK Germany

HS Code

3822000002

NFPA 704

	0
2		0

Dextromethorphan hydrobromide monohydrate price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D2531	Dextromethorphan hydrobromide monohydrate ≥99% (TLC)	6700-34-1	5g	$80.7	2024-03-01	Buy
Sigma-Aldrich	D0740000	Dextromethorphan hydrobromide European Pharmacopoeia (EP) Reference Standard	6700-34-1	D0740000	$168	2024-03-01	Buy
Sigma-Aldrich	1181007	Dextromethorphan hydrobromide United States Pharmacopeia (USP) Reference Standard	6700-34-1	500mg	$436	2024-03-01	Buy
Cayman Chemical	13950	Dextromethorphan (hydrobromide hydrate) ≥98%	6700-34-1	50mg	$32	2024-03-01	Buy
Cayman Chemical	13950	Dextromethorphan (hydrobromide hydrate) ≥98%	6700-34-1	100mg	$61	2024-03-01	Buy

Product number	Packaging	Price	Buy
D2531	5g	$80.7	Buy
D0740000	D0740000	$168	Buy
1181007	500mg	$436	Buy
13950	50mg	$32	Buy
13950	100mg	$61	Buy

Dextromethorphan hydrobromide monohydrate Chemical Properties,Uses,Production

Description

Dextromethorphan (DXM) is a dextratrorotatory morphinan with structural similarity to levorphanol, codeine, and morphine. Because of its strong antitussive effects, dextromethorphan is widely used as a cough suppressant. However, it does not provoke opioid activity as is characteristic of several other morphine derivatives. DXM binds to and inhibits NMDA (IC₅₀ = 0.55 μM) and nicotinic receptors (IC₅₀s = 0.7-3.9 μM) and blocks receptor-gated and voltage-gated calcium channels (IC₅₀ = 60 μM) and voltage-gated sodium channels (IC₅₀ = 78 μM). DXM has been used in multimodal analgesic therapies for acute and neuropathic pain.

Chemical Properties

White Solid

Uses

An antitussive drug. Orally active synthetic morphine analog. Analgesic (narcotic). Racemethorphan and levomethorpham are controlled substances (opiates).

Uses

Antitussive;Opioid ligand

Definition

ChEBI: Dextromethorphan hydrobromide is the hydrobromide and monohydrate of the antitussive drug dextromethorphan. It is a hydrate and a hydrobromide. It contains a dextromethorphan.

brand name

Benylin DM (Parke-Davis); Dextromethorphan Hydrobromide OROS Tablets (Ciba-Geigy); Drixoral Cough (Schering-Plough HealthCare); PediaCare 1 (McNeil Consumer); Romilar (Hoffmann-LaRoche-International); St. Joseph Cough Syrup (Schering-Plough HealthCare).

Biological Activity

Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.

Dextromethorphan hydrobromide monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Dextromethorphan hydrobromide monohydrate Suppliers

Global( 294)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan senwayer century chemical Co.,Ltd	+undefined-27-86652399 +undefined13627115097	market02@senwayer.com	China	874	58
Dorne Chemical Technology co. LTD	+86-13583358881 +86-18560316533	Ethan@dornechem.com	China	294	58
Shandong Hanjiang Chemical Co., Ltd	+86-0533-2066820 +8618369939125	hanson@sdhanjiang.com	China	1527	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Jimi Trading Co., Ltd.	+86 319 5273535	bestoneforyou@sina.com	CHINA	288	58

Supplier	Advantage
Wuhan senwayer century chemical Co.,Ltd	58
Dorne Chemical Technology co. LTD	58
Shandong Hanjiang Chemical Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing Finetech Chemical Co., Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Jimi Trading Co., Ltd.	58

View Lastest Price from Dextromethorphan hydrobromide monohydrate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-27	Dextromethorphan hydrobromide monohydrate 6700-34-1	US $1.00 / g	1g	99%	10 Tons	Dorne Chemical Technology co. LTD
2024-04-12	Dextromethorphan hydrobromide monohydrate 6700-34-1	US $0.00 / kg	1kg	0.99	10T	Shandong Hanjiang Chemical Co., Ltd
2023-11-27	Dextromethorphan HBR 6700-34-1	US $585.00 / KG	1KG	99% min	20 TONS	Wuhan Senwayer Century Chemical Co.,Ltd

Dextromethorphan hydrobromide monohydrate
6700-34-1
US $1.00 / g
99%
Dorne Chemical Technology co. LTD

Dextromethorphan hydrobromide monohydrate
6700-34-1
US $0.00 / kg
0.99
Shandong Hanjiang Chemical Co., Ltd

Dextromethorphan HBR
6700-34-1
US $585.00 / KG
99% min
Wuhan Senwayer Century Chemical Co.,Ltd

Dextromethorphan hydrobromide monohydrate Spectrum

Dextromethorphan hydrobromide monohydrate(6700-34-1)MS Dextromethorphan hydrobromide monohydrate(6700-34-1)IR1 Dextromethorphan hydrobromide monohydrate(6700-34-1)IR2

6700-34-1(Dextromethorphan hydrobromide monohydrate)Related Search:

MELIBIOSE Dextromethorphan D-Glucose monohydrate Citric acid monohydrate 3-Isobutyl-1H-pyrazole-5-carboxylic acid

1,4,5,6-TETRAHYDRO-CYCLOPENTAPYRAZOLE-3-CARBOXYLIC ACID Ethyl 3-n-propylpyrazole-5-carboxylate 1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 3-CYCLOPROPYLPYRAZOLE-5-CARBOXYLIC ACID 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID

Dextromethorphan Hydrobromide INDAZOLE-3-CARBOXYLIC ACID Hydrogen bromide 4,5,6,7-TETRAHYDRO-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER 1H-Pyrazole-3-carboxylicacid,1-methyl-5-propyl-,ethylester(9CI)

2-METHYL-4,5,6,7-TETRAHYDRO-2H-INDAZOLE-3-CARBOXYLIC ACID 4,5,6,7,8,9-HEXAHYDRO-1H-CYCLOOCTAPYRAZOLE-3-CARBOXYLIC ACID 1H-Pyrazole-3-carboxylicacid,1-methyl-5-propyl-(9CI)

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DMHM (9α,13α,14α)-3-Methoxy-17-MethylMorphinan HydrobroMide Hydrate 3-Methoxy-17-Methyl-9α,13α,14α-Morphinan HydrobroMide Hydrate d-3-Methoxy-N-MethylMorphinan HydrobroMide Monohydrate DextroMethorphan hydrobroMide:Monohydrat Morphinan,3-Methoxy-17-Methyl-, hydrobroMide, hydrate (1:1:1), (9a,13a,14a)- D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE DEXTROMETHORPHAN HYDROBROMIDE MONOHYDRATE DEXTROMETHORPHAN HYDROBROMIDE, PH EUR DEXTROMETHORPHAN HYDROBROMIDE*MONOHYDRAT E USP D-Methorphan hydrobromide monohydrate Morphinan, 3-methoxy-17-methyl-, hydrobromide, monohydrate, (9.alpha.,13.alpha.,14.alpha.)- Dextromethorphan hydrobromicum, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide Dextromethorphan monohydrate hydrobromide Dextromethorphan monohydrate hydrobromide, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide (9α,13α,14α)-3-Methoxy-17-methylmorphinanhydrobromide Dextromethorphan hydrobromide monohydrate,(9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide, Dextromethorphan hydrobromicum Dextromethorphan hydrobromide monohydrate,(9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide, d-3-Methoxy-N-methylmorphinan hydrobromide monohydrate, Dextromethorphan hydrobromide monohydrate Dextromethorphan Hydrobromide (500 mg) Certified Reference Material (CRM) Dextromethorphan Hydrobromide (500 mg) Dextromethorphan hyd DextroMethorphan HydrobroMide (Certified Reference Material (CRM)) DextroMethorphan HydrobroMide, Monohydrate, USP, EP (+)-3-Methoxy-N-MethylMorphinan HydrobroMide Monohydrate Morphinan,3-methoxy-17-methyl- Dextromethorphani Hydrobromidum High quality pure dextromethorphan hydrochloride powder Dextromethorphan hydrobromide monohydrate USP/EP/BP Dextromethorphan Hydrobromide MonohydrateQ: What is Dextromethorphan Hydrobromide Monohydrate Q: What is the CAS Number of Dextromethorphan Hydrobromide Monohydrate Q: What is the storage condition of Dextromethorphan Hydrobromide Monohydrate Q: What are the applications of Dextromethorphan Hydrobromide Monohydrate Dextromethorphan Hydrobromide (1181007) Dextromethorphan Hydrobromide dextrorotation dextromethorphansigmareference*standard DextroMethorphan hydrobroMide hydrate Dextromethorphan HBr monohydrate (9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN HYDROBROMIDE, D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE MONOHYDRATE Pharmaceutical Dextromethorphan Hydrobromide Monohydrate DEXTROMETHORPHAN HBr IP (4bS,8aS,9S)-3-methoxy-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene hydrobromide hydrate Dexmesophane hydrobromide monohydrate 6700-34-1 C18H28BrNO2 C18H25NOHBrH2O 37032 C18H30BrNO3 Allosteric antagonist at NMDA-controlled ion channels; antagonist at voltage-dependent channels Complex Molecules Asymmetric Synthesis Chiral Building Blocks Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Other APIs