3'-fluoro-3'-deoxyadenosine
- CAS No.
- 75059-22-2
- Chemical Name:
- 3'-fluoro-3'-deoxyadenosine
- Synonyms
- 3'-F-3'-rA;3'-fluoro-3'-deoxyadenosine;3'-fluoro-3'-deoxyadenosine;3’-Deoxy-3’-fluoro adenosine;Adenosine, 3'-deoxy-3'-fluoro-;(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
- CBNumber:
- CB61333211
- Molecular Formula:
- C10H12FN5O3
- Molecular Weight:
- 269.23
- MDL Number:
- MFCD20134043
- MOL File:
- 75059-22-2.mol
- MSDS File:
- SDS
| Melting point | 211-212 °C |
|---|---|
| Boiling point | 628.6±65.0 °C(Predicted) |
| Density | 2.01±0.1 g/cm3(Predicted) |
| pka | 12.45±0.70(Predicted) |
| InChI | InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1 |
| InChIKey | QCDAWXDDXYQEJJ-QYYRPYCUSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1F |
3'-fluoro-3'-deoxyadenosine price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D239975 | 3''-Deoxy-3''-fluoroadenosine | 75059-22-2 | 10mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | ND15616 | 3'-Deoxy-3'-fluoroadenosine | 75059-22-2 | 25mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | ND15616 | 3'-Deoxy-3'-fluoroadenosine | 75059-22-2 | 5mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | ND15616 | 3'-Deoxy-3'-fluoroadenosine | 75059-22-2 | 10mg | $125 | 2021-12-16 | Buy |
| AK Scientific | 8706CA | 3'-Fluoro-3'-deoxyadenosine | 75059-22-2 | 5mg | $151 | 2021-12-16 | Buy |
3'-fluoro-3'-deoxyadenosine Chemical Properties,Uses,Production
Uses
3'-deoxy-3'-fluoroadenosine can be used as pharmaceutical intermediates for pharmaceutical experimental research.
Biological Activity
3'-Fluoro-3'-deoxyadenosine was active against a broad range of viruses, encompassing both DNA viruses [pox (vaccinia)], single-stranded (+) RNA viruses [picorna (polio, Coxsackie B), toga (sindbis, Semliki Forest)] and double-stranded RNA viruses (reo). Its antiviral activity spectrum, 3'-fluoro-3'-deoxyadenosine, clearly differed from those adenosine analogs known as inhibitors of S-adenosylhomocysteine hydrolase. 3'-Fluoro-3'-deoxyadenosine also proved effective in vivo in inhibiting tail lesion formation in mice inoculated intravenously with vaccinia virus[1].
References
[1] A. Van Aerschot. “Synthesis and antiviral activity evaluation of 3′-fluoro-3′-deoxyribonucleosides: broad-spectrum antiviral activity of 3′-fluoro-3′-deoxyadenosine.” Antiviral research 12 3 (1989): Pages 133-150.
3'-fluoro-3'-deoxyadenosine Preparation Products And Raw materials
Raw materials
Preparation Products
3'-fluoro-3'-deoxyadenosine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 10026 | 58 |
| PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD | 0371-55159968 18137130222 | haifeng.zhang@pannacean.com | China | 387 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |