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Sulfathiazole

Sulfathiazole
Sulfathiazole structure
CAS No.
72-14-0
Chemical Name:
Sulfathiazole
Synonyms
ST;Sulzol;Duatok;Dulana;m&b760;m+b760;rp2090;Cerazol;Cibazol;M&B 760
CBNumber:
CB6133470
Molecular Formula:
C9H9N3O2S2
Formula Weight:
255.32
MOL File:
72-14-0.mol

Sulfathiazole Properties

Melting point:
200-202 °C(lit.)
Boiling point:
479.5±47.0 °C(Predicted)
Density 
1.4629 (rough estimate)
refractive index 
1.6560 (estimate)
storage temp. 
0-6°C
solubility 
0.5g/l
pka
7.2(at 25℃)
form 
neat
Water Solubility 
Insoluble (<0.1 g/100 mL at 21 ºC)
Merck 
14,8943
BRN 
226178
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
JNMRHUJNCSQMMB-UHFFFAOYSA-N
CAS DataBase Reference
72-14-0(CAS DataBase Reference)
NIST Chemistry Reference
Sulfathiazole(72-14-0)
EPA Substance Registry System
Sulfathiazole (72-14-0)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  3249
WGK Germany  2
RTECS  WP2360000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29350090

Sulfathiazole price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 46902 Sulfathiazole VETRANAL 72-14-0 250mg-r $46.3 2019-12-02 Buy
Sigma-Aldrich 1636504 Sulfathiazole United States Pharmacopeia (USP) Reference Standard 72-14-0 350mg $352.8 2019-12-02 Buy
TCI Chemical S0272 Sulfathiazole >98.0%(HPLC)(T) 72-14-0 25g $16 2019-12-02 Buy
TCI Chemical S0272 Sulfathiazole >98.0%(HPLC)(T) 72-14-0 100g $41 2019-12-02 Buy
Alfa Aesar A10727 Sulfathiazole, 99% 72-14-0 100g $45.4 2019-12-02 Buy

Sulfathiazole Chemical Properties,Uses,Production

Chemical Properties

white to cream powder

Uses

Sulfonamide antibacterial.

Definition

ChEBI: A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position.

brand name

Argazol;Bucosol;Chemiovis;Coryza;Crionil;Csp 500;Csp-250;Edifeno;Femakzem;Formotablin antidiarreico;Gyne-sulf;Gyn-sulf;Neosutrin;Polvos wilfe;Pomada wilfe;Prothiazol;Septex cream no. 2;Streptacillin;Sulfa-orzon;Sulfazol;Sulfhatose;Sulfintestin;Sulfopyrol;Sulfour;Sulfzol;Sulnac;Sulphatriad;Tampovagan pss;Thiadyl;Thiuramide;Tiadyl;Trimeto;Trisulpha;Trysul;Tylasul;Ufa 902-duo;Vetoprim mi;Wintrazol.

World Health Organization (WHO)

Sulfathiazole, a sulfonamide anti-infective agent, was introduced more than 25 years ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Although preparations remain available, use of the drug has been discontinued in many countries.

General Description

White crystalline powder. Is dimorphous: form I is consists of prismatic rods and form II of six-sided plates and prisms. Insoluble in water and soluble in dil aqueous acid and aqueous base.

Air & Water Reactions

May be sensitive to heat, air and light during long-term storage . Insoluble in water.

Reactivity Profile

Sulfathiazole is an amino acid.

Fire Hazard

Flash point data for Sulfathiazole are not available, but Sulfathiazole is probably combustible.

Pharmaceutical Applications

2-Sulfanilamidothiazole. A short-acting compound (half-life c. 4 h) with relatively high activity. Protein binding is c. 75%. Its use has declined because of a high incidence of side effects. It is one of the constituents of triple sulfonamide mixtures, of which local preparations are still available.
Two compounds, phthalylsulfathiazole (sulfathalidine) and succinylsulfathiazole (sulfasuxidine) owe their activity to the slow liberation of sulfathiazole in the bowel. They are poorly soluble and very little is absorbed after oral administration. They were formerly used in the treatment of intestinal infections and in bowel preparation before surgery. They are available in multi-ingredient preparations in some countries.

Safety Profile

Human poison by unspecified route. Experimental poison by intraperitoneal route, Moderately toxic by intravenous, subcutaneous, and parenteral routes. Mildly toxic by ingestion. Human systemic effects by unspecified route: conjunctiva irritation, tubule changes, and allergic skin dermatitis. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data, Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Sulfathiazole Preparation Products And Raw materials

Raw materials

Preparation Products


Sulfathiazole Suppliers

Global( 223)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21680 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29996 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23981 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
Shandong chuangyingchemical Co., Ltd.
13156170209
sale@chuangyingchem.com CHINA 4405 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63729 58

View Lastest Price from Sulfathiazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-18 Sulfathiazole
72-14-0
US $7.00 / kg 1kg 99% 100KG career henan chemical co
2018-12-18 Sulfathiazole
72-14-0
US $7.00 / kg 1kg 99% 100KG career henan chemical co

Sulfathiazole Spectrum


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