DEBRISOQUIN SULFATE
- CAS No.
- 581-88-4
- Chemical Name:
- DEBRISOQUIN SULFATE
- Synonyms
- Tendor;declinax;RO 5-3307;RO 5-33071;Debrisoquina;Debrisochinum;ebrisoquinsulfate;DEBRISOQUIN SULFATE;DEBRISOQUINE SULFATE;isocaramidinesulfate
- CBNumber:
- CB6133940
- Molecular Formula:
- C20H28N6O4S
- Molecular Weight:
- 448.54
- MDL Number:
- MFCD00153791
- MOL File:
- 581-88-4.mol
| Melting point | 278-280°, 284-285° or 266-268° (H2O) |
|---|---|
| storage temp. | room temp |
| solubility | H2O: 20 mg/mL with heat |
| form | Solid |
| color | Pale Yellow |
| FDA UNII | Q94064N9NW |
DEBRISOQUIN SULFATE price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D1306 | Debrisoquine sulfate | 581-88-4 | 100mg | $280 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP103 | Debrisoquine sulfate British Pharmacopoeia (BP) Reference Standard | 581-88-4 | 100MG | $266 | 2024-03-01 | Buy |
| Cayman Chemical | 29568 | Debrisoquin (hemisulfate) | 581-88-4 | 10mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 29568 | Debrisoquin (hemisulfate) | 581-88-4 | 250mg | $595 | 2024-03-01 | Buy |
| Cayman Chemical | 29568 | Debrisoquin (hemisulfate) | 581-88-4 | 50mg | $155 | 2024-03-01 | Buy |
DEBRISOQUIN SULFATE Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Declinax,Roche,UK,1967
Uses
Antihypertensive.
Manufacturing Process
27 g of 1,2,3,4-tetrahydroisoquinoline was added at room temperature to a
solution of 28 g of 2-methyl-2-isothiourea sulfate in 80 ml of water. The
resulting mixture was kept at room temperature with occasional shaking. After
a short period of time, methylmercaptan began to escape, and the mixture
warmed up slightly. After then standing for 24 hours, crystals formed. They
were filtered off and rinsed with ice cold water. Recrystallization from
approximately 100 ml of water yielded 1,2,3,4-tetrahydroisoquinoline-2-
carboxamidine sulfate melting at 278°C to 280°C (uncorr.).
Another batch prepared in the same manner melted at 284°C to 285°C due to
a minute difference in moisture content.
Both batches prepared above analyzed correctly for (C10H13N3)2·H2SO4.
brand name
Declinax (HoffmannLaRoche).
Therapeutic Function
Antihypertensive
Biochem/physiol Actions
Debrisoquine is an anti-hypertensive agent. It is metabolized by cytochrome P4502D6.
DEBRISOQUIN SULFATE Preparation Products And Raw materials
DEBRISOQUIN SULFATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55672 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |