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4-Chloro-N-methylpicolinamide

4-Chloro-N-methylpicolinamide structure

CAS No.: 220000-87-3

Chemical Name:: 4-Chloro-N-methylpicolinamide

Synonyms: 4-Chloro-N-methylpicolinamide;4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE;4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE;oro-N-methyL;Sorafenib INT3;4-Chloropyridine-2;IFLAB-BB F2108-0189;-2-pyridinecarboxamide;Sorafenib impurities13;Sorafenib tosylate INT II

CBNumber:: CB6134053

Molecular Formula:: C7H7ClN2O

Molecular Weight:: 170.6

MDL Number:: MFCD02185921

MOL File:: 220000-87-3.mol

MSDS File:: SDS

Last updated:2024-03-28 14:26:51

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4-Chloro-N-methylpicolinamide Properties

Melting point	41-43°C
Boiling point	317.8±27.0 °C(Predicted)
Density	1.264±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form	Solid
pka	13.41±0.46(Predicted)
color	Off-White to Light Yellow
CAS DataBase Reference	220000-87-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

22-36

Safety Statements

HS Code

2933399990

NFPA 704

	1
2		0

4-Chloro-N-methylpicolinamide price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C2793	4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T)	220000-87-3	1g	$33	2024-03-01	Buy
TCI Chemical	C2793	4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T)	220000-87-3	5g	$132	2024-03-01	Buy
Alfa Aesar	H50535	4-Chloro-N-methylpyridine-2-carboxamide, 97%	220000-87-3	250mg	$64.65	2024-03-01	Buy
Alfa Aesar	H50535	4-Chloro-N-methylpyridine-2-carboxamide, 97%	220000-87-3	1g	$216.65	2024-03-01	Buy
TRC	C379950	4-Chloro-N-methylpyridine-2-carboxamide(>90%)	220000-87-3	25g	$440	2021-12-16	Buy

Product number	Packaging	Price	Buy
C2793	1g	$33	Buy
C2793	5g	$132	Buy
H50535	250mg	$64.65	Buy
H50535	1g	$216.65	Buy
C379950	25g	$440	Buy

4-Chloro-N-methylpicolinamide Chemical Properties,Uses,Production

Description

4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.

Chemical Properties

Pale-Yellow Solid

Uses

4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.

4-Chloro-N-methylpicolinamide synthesis

Synthesis of 4-Chloro-N-methylpicolinamide from Methyl 4-chloropicolinate and Methylamine

4-Chloro-N-methylpicolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-CHLORO-N,N-DIMETHYL-PYRIDINE-2-CARBOXAMIDE 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

4-Chloro-N-methylpicolinamide Suppliers

Global( 532)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd	+86-18752526868	jennysun@yzqyyykj.com	China	64	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	951	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	885	50
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55

Supplier	Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
hebei hongtan Biotechnology Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Nanjing Finetech Chemical Co., Ltd.	55

View Lastest Price from 4-Chloro-N-methylpicolinamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-25	N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3	US $12.00 / KG	1KG	99%	100mt	Jinan Finer Chemical Co., Ltd
2024-04-22	N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3	US $30.00 / kg	1kg	98%	2000kg	hebei hongtan Biotechnology Co., Ltd
2024-04-10	N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3	US $0.00 / kg	1kg	98%	500kg	Shanghai Joiny Pharmaceutical Co.,LTD

N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
US $12.00 / KG
99%
Jinan Finer Chemical Co., Ltd

N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
US $30.00 / kg
98%
hebei hongtan Biotechnology Co., Ltd

N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
US $0.00 / kg
98%
Shanghai Joiny Pharmaceutical Co.,LTD

4-Chloro-N-methylpicolinamide Spectrum

N-Methyl-4-chloropyridine-2-carboxamide(220000-87-3)¹HNMR

220000-87-3(4-Chloro-N-methylpicolinamide)Related Search:

Methylparaben N,N-Dimethylformamide Thiophanate-methyl Kresoxim-methyl Methyl acrylate

Methyl acetate Bensulfuron methyl N-Methylformamide 2-Picoline PYRIDINE-2-CARBOXAMIDE

2,2'-(Butylimino)diethanol N-Benzylethanolamine 3-Amino-2-chlorobenzotrifluoride Methyl Sorafenib IMpurity

Sorafenib related coMpound 8 Sorafenib related compound 10 Sorafenib Related Compound 21

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IFLAB-BB F2108-0189 N-METHYL-4-CHLORO-PYRIDINE-2-CARBOXAMIDE 4-CHLORO-N-MENTHYLPHCOLINAMIDE 4-Chloropyridine-2-carboxylic acid methylamide N-Methyl-4-chloro-2-pyridinecarboxamide N-Methyl-4-chloropicolinamide 4-Chloro-(2-(methylamino)-carbonyl)-pyridine N-Methyl-4-chloropyridine-2-carboxylate 4-chloro-n-Methyl-2-pyriMidine carboxaMide 2-PyridinecarboxaMide, 4-chloro-N-Methyl- 2-(N-MethylcarbaMoyl)-4-chloropyridine 4-Chloro-N-Methylpyridine-2-CarboxaMide 2-carboxaMide 4-Chloro-N-Methylpyridine-2-carboxaMide (>90%) 4-Chloro-N-Methyl-2-pyridinecarboxaMide, >95% 4-Chloro-N-methylpyridine-2-carboxamide Sorafenib INT3 4-Chloropyridine-2 4-Chloro-N-methyl-2-pyridinecarboxamide Sorafenib Intermediates I Sorafenib tosylate INT II 4-Chloro-N-methyl-2-pyridinecarboxamide 97% 4-Chloro-N-methyl-2-pyridinecarboxamide > oro-N-methyL -2-pyridinecarboxamide 4-CHLORO-N-METHYL-2-PYRIDENECARBOXAMIDE N-Methyl-4-chloropyridine-2-carboxamide ISO 9001：2015 REACH Sorafenib tosylate Impurity P 4-Chloro-N-methyl-2-pyridinecarboxamide (Sorafenib Impurity) Sorafenib impurities13 (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide)Q: What is (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What is the CAS Number of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What is the storage condition of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What are the applications of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) N-Methyl-4-chloropyridine-2-carboxamide(220000-87-3) 4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE 4-Chloro-N-methylpicolinamide 4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE Sorafenib Impurity INT-1-B 4-Chloro-N-methylpyridine-2-carboxamide,97% 220000-87-3 Pyridine Amines Aromatics Heterocycles blocks Carboxes Pyridines 220000-87-3