ChemicalBook >> CAS DataBase List >>Tilorone dihydrochloride

Tilorone dihydrochloride

CAS No.
27591-69-1
Chemical Name:
Tilorone dihydrochloride
Synonyms
Flu;Deae-f;nsc-143969;Rmi 10008da;TILORONE 2HCL;Tilorone DiHCl;TILORONE HYDROCHLORIDE;Tilolone hydrochloride;2,7-Bis-deae-fluorenone;TILORONE DIHYDROCHLORIDE
CBNumber:
CB6144470
Molecular Formula:
C25H36Cl2N2O3
Molecular Weight:
483.47
MDL Number:
MFCD00134071
MOL File:
27591-69-1.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:36

Tilorone dihydrochloride Properties

Melting point 230-233 °C(lit.)
storage temp. Sealed in dry,Room Temperature
solubility Methanol (Slightly)
form Solid
color Orange
Merck 14,9440
InChIKey BSVYJQAWONIOOU-UHFFFAOYSA-N
CAS DataBase Reference 27591-69-1(CAS DataBase Reference)
FDA UNII BJ507J4LKY

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335-H351
Precautionary statements  P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38-40
Safety Statements  7-22-26-37/39
WGK Germany  3
RTECS  LL9000000
HS Code  2922.39.4500
Toxicity LD50 in mice, rats (single dose): 959, 852 mg/kg orally; 145, 244 mg/kg i.p. (Krueger, Mayer)
NFPA 704
0
3 0

Tilorone dihydrochloride price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 220957 Tilorone dihydrochloride 95% 27591-69-1 100mg $175 2024-03-01 Buy
TCI Chemical T2836 Tilorone Dihydrochloride >98.0%(HPLC)(T) 27591-69-1 100mg $97 2024-03-01 Buy
TCI Chemical T2836 Tilorone Dihydrochloride >98.0%(HPLC)(T) 27591-69-1 1g $391 2024-03-01 Buy
Cayman Chemical 17868 Tilorone (hydrochloride) ≥98% 27591-69-1 50mg $37 2024-03-01 Buy
Cayman Chemical 17868 Tilorone (hydrochloride) ≥98% 27591-69-1 1g $353 2024-03-01 Buy
Product number Packaging Price Buy
220957 100mg $175 Buy
T2836 100mg $97 Buy
T2836 1g $391 Buy
17868 50mg $37 Buy
17868 1g $353 Buy

Tilorone dihydrochloride Chemical Properties,Uses,Production

Description

Tilorone is an orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions. With chronic administration, tilorone induces lysosomal glycosaminoglycan storage, rendering glycosaminoglycans resistant to enzymatic degradation.

Chemical Properties

Orange-yellow crystalline powder

Uses

Tilorone dihydrochloride was used to study the interaction of drugs with synthetic self-complementary DNA by SPR (Surface Plasmon Resonance).

Uses

Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

Definition

ChEBI: Tilorone dihydrochloride is the dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS. It has a role as an anti-inflammatory agent, an antineoplastic agent, an interferon inducer, a nicotinic acetylcholine receptor agonist and an antiviral drug. It contains a tilorone(2+).

brand name

Tilorone is INN.

General Description

Effect of tilorone dihydrochloride on the changes of transmembrane potential of mitochondrial membranes of the isolated rat hepatocytes has been investigated. Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

27591-97-5
27591-69-1
Synthesis of Tilorone dihydrochloride from Tilorone

Tilorone dihydrochloride Preparation Products And Raw materials

Global( 178)Suppliers
Supplier Tel Email Country ProdList Advantage
Mascot I.E.Co .,Ltd.
China 303 58
Shandong Xingshun New Material Co., Ltd.
+86-0519-86464994 +86-13515263029 gxy@xingshengtech.com China 552 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3422 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12468 58

View Lastest Price from Tilorone dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tilorone dihydrochloride pictures 2022-09-17 Tilorone dihydrochloride
27591-69-1
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Tilorone dihydrochloride pictures 2021-09-29 Tilorone dihydrochloride
27591-69-1
US $0.00 / KG 1KG 99%,USP 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Tilorone dihydrochloride USP/EP/BP pictures 2021-07-16 Tilorone dihydrochloride USP/EP/BP
27591-69-1
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
TILORONE HYDROCHLORIDE 2,7-BIS[2-(DIETHYLAMINO)ETHOXY]-9-FLUORENONE DIHYDROCHLORIDE TILORONE 2HCL 2,7-Bis-deae-fluorenone 9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride Deae-f Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride Rmi 10008da Tilorone DiHCl nsc-143969 TILORONE DIHYDROCHLORIDE 2,7-bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one dihydrochloride 2,7-bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one hydrochloride Tilorone dihydrochloride 95% 2,7-bis(2-(diethylamino)ethoxy)-9h-fluoren-9-ondihydrochloride 2,7-bis(2-(diethylamino)ethoxy)-fluoren-9-ondihydrochloride 2,7-bis(2-(diethylamino)ethoxy)-fluoren-9-onedihydrochloride bis-deae-fluorenonehydrochloride Flu Tilorone dihydrochloride USP/EP/BP Tilorone dihydrochloride cas 27591-69-1 Tilorone Dihydrochloride Tilorone Dihydrochloride Tilolone hydrochloride 27591-69-1 C25H36N2O3Cl2 C25H36Cl2N2O3 C25H36O3N22HCl C25H34N2O32HCl C25H35ClN2O3 Building Blocks Carbonyl Compounds C15 to C38 Ketones Organic Building Blocks C15 to C38 Carbonyl Compounds Chemical Synthesis Ketones Organic Building Blocks strong recommend Fluorene series Building Blocks Fused Ring Systems