ChemicalBook >> CAS DataBase List >>3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide structure

CAS No.: 199666-03-0

Chemical Name:: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

Synonyms: CS-1828;R061-8048;Ro 61-8048, >=98%;Ro 61-8048 ，S8172;Ro 61-8048 >=98% (HPLC);Ro 61-8048 (Ro-61-8048);Ro 61-8048, 10 mM in DMSO;KMO Inhibitor I, Ro 61-8048;Ro 61-8048, kynurenine 3-monooxygenase (KMO) inhibitor;KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem

CBNumber:: CB61458468

Molecular Formula:: C17H15N3O6S2

Molecular Weight:: 421.45

MDL Number:: MFCD11040807

MOL File:: 199666-03-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-21 10:31:43

Product description	Number	Pack Size	Price
Ro 61-8048 ≥98% (HPLC)	SML0233	5mg	$146
KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem	420360-M	10mg	$155
KMO Inhibitor I, Ro 61-8048 The KMO Inhibitor I, Ro 61-8048, also referenced under CAS 199666-03-0, controls the biological activity of KMO. This small molecule/inhibitor is primarily used for Neuroscience applications.	420360-M	1 unit	$145
KMO Inhibitor I, Ro 61-8048	420360-M	10mg-m	$135
Ro 61-8048 ≥98%	15199	5mg	$90
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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Properties

Melting point	185℃
Boiling point	627.4±65.0 °C(Predicted)
Density	1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	2-8°C
solubility	DMSO: ≥15mg/mL
form	Yellow solid
pka	6.29±0.10(Predicted)
color	faint yellow to yellow
InChI	1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
InChIKey	NDPBMCKQJOZAQX-UHFFFAOYSA-N
SMILES	COc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)-c3cccc(c3)[N+]([O-])=O
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H319

Precautionary statements

P305+P351+P338

Hazard Codes

Risk Statements

25-36

Safety Statements

26-45

WGK Germany

Storage Class

11 - Combustible Solids

NFPA 704

	0
2		0

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0233	Ro 61-8048 ≥98% (HPLC)	199666-03-0	5mg	$146	2026-04-30	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem	199666-03-0	10mg	$155	2026-04-30	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048 The KMO Inhibitor I, Ro 61-8048, also referenced under CAS 199666-03-0, controls the biological activity of KMO. This small molecule/inhibitor is primarily used for Neuroscience applications.	199666-03-0	1 unit	$145	2025-07-31	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048	199666-03-0	10mg-m	$135	2021-12-16	Buy
Cayman Chemical	15199	Ro 61-8048 ≥98%	199666-03-0	5mg	$90	2026-04-30	Buy

Product number	Packaging	Price	Buy
SML0233	5mg	$146	Buy
420360-M	10mg	$155	Buy
420360-M	1 unit	$145	Buy
420360-M	10mg-m	$135	Buy
15199	5mg	$90	Buy

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Chemical Properties,Uses,Production

Uses

Ro 61-8048 is a potent and competitive kynurenine 3-monooxygenase (KMO) inhibitor.

Definition

ChEBI: Ro 61-8048 is a C-nitro compound.

Biological Activity

Potent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.

Biochem/physiol Actions

Ro 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.

storage

+4°C

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Suppliers

Global( 129)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	8614	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Coresyn Pharmatech Co., Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58

View Lastest Price from 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-21	Ro 61-8048 199666-03-0	US $33.00-70.00 / mg		99.87%	10g	TargetMol Chemicals Inc.
	2019-09-05	3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 199666-03-0	US $1.00 / ASSAYS	1ASSAYS	98%	10kg	Career Henan Chemical Co

Ro 61-8048
199666-03-0
US $33.00-70.00 / mg
99.87%
TargetMol Chemicals Inc.

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
199666-03-0
US $1.00 / ASSAYS
98%
Career Henan Chemical Co

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Spectrum

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide(199666-03-0)¹HNMR

199666-03-0(3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide)Related Search:

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ROC-325 RO2959 Hydrochloride

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Ro 61-8048, >=98% RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048 RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide KMO Inhibitor I, Ro 61-8048 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide 3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide 3,4-Dimethoxy-N-4-(3-nitro-phenyl)-thiazol-2-yl-benzenesulfomide R061-8048 KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem CS-1828 Benzenesulfonamide, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]- Ro 61-8048 >=98% (HPLC) NMDA,Ro 61 8048,inhibit,Ro 61-8048,dystonia,Inhibitor,hydroxylase,Ro 618048,kynurenine 3,4-dimethoxy 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Ro 61-8048, kynurenine 3-monooxygenase (KMO) inhibitor Ro 61-8048, 10 mM in DMSO Ro 61-8048 ，S8172 Ro 61-8048 (Ro-61-8048) 199666-03-0 C17H15N3O6S2 Inhibitors