magnolamine

CAS No.
573-73-9
Chemical Name:
magnolamine
Synonyms
magnolamine;(1S)-1,2,3,4-Tetrahydro-1-[[4-[4-hydroxy-5-methoxy-2-[[(1S)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methylisoquinolin-7-ol;7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-[4-hydroxy-5-methoxy-2-[[(1S)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methyl-, (1S)-
CBNumber:
CB61480618
Molecular Formula:
C37H42N2O7
Molecular Weight:
626.74
MDL Number:
MOL File:
573-73-9.mol
MSDS File:
SDS
Last updated:2023-07-14 17:44:55

magnolamine Properties

Melting point 117-9°C
Boiling point 768.0±60.0 °C(Predicted)
Density 1.254±0.06 g/cm3(Predicted)
pka 10.12±0.25(Predicted)

magnolamine Chemical Properties,Uses,Production

Description

This bisbenzylisoquinoline alkaloid is found in the benzene-soluble portion of the total alkaloids extracted from Magnolia fuscata. When recrystallized from C6H6 it yields fine, colourless needles, soluble in alkalies, CHC13 and EtOH. It is dextrorotatory with [α]D + 111.6° and yields a crystalline picrate, m.p. 142- SoC (dec.); a picrolonate, m.p. 163-4°C and a tetramethyl ether, m.p. lSI-2°C. The latter may be oxidized by KMn04 in Me2CO to give 1-keto-6:7-dimethoxy- 2-methyltetrahydroisoquinoline, m.p. 124-5°C and magnolaminic acid, C16H1407, m.p. 280-loC. The alkaloid acts as a cardiac depressant at between 10 to 500 parts per million.

References

Proskurnina, Orekhov., Bull. Soc. Chim., 5, 1357 (1938) Proskurnina., J. Gen. Chem. USSR., 16, 129 (1946) Tomita.,J. Pharm. Soc., Japan, 1075 (1951) Tomita, Kugo., Chem. Abstr., SO, 1056 (1956) Pharmacology: Buchi., Schweiz. Apoth. Zeit., 83, 198 (1945)

magnolamine Preparation Products And Raw materials

Raw materials

Preparation Products

magnolamine Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd.
55
magnolamine (1S)-1,2,3,4-Tetrahydro-1-[[4-[4-hydroxy-5-methoxy-2-[[(1S)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methylisoquinolin-7-ol 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-[4-hydroxy-5-methoxy-2-[[(1S)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methyl-, (1S)- 573-73-9 C36H40N2O7 C37H42N2O7