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6-aminotetralin-2,3-diol

CAS No.
13575-86-5
Chemical Name:
6-aminotetralin-2,3-diol
Synonyms
ADTN hydrobromide;6-aminotetralin-2,3-diol;6,7-Dihydroxy-2-aminotetraline hydrobromide;Aminotetraline hydrobromide, 6,7-Dihydroxy-2-;6-Amino-5,6,7,8-tetrahydro-2,3-naphthalenediolhydrobromide;(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthaleneHydrobromide
CBNumber:
CB61513738
Molecular Formula:
C10H13NO2
Molecular Weight:
0
MDL Number:
MFCD00036982
MOL File:
13575-86-5.mol
MSDS File:
SDS
Last updated:2023-07-21 08:27:59

6-aminotetralin-2,3-diol Properties

Melting point 270-271 °C
storage temp. 2-8°C
solubility Soluble in Water (up to 25 mg/ml)
form solid
color Tan
Stability Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.
FDA UNII U1P469341B

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
NFPA 704
0
2 0

6-aminotetralin-2,3-diol price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23866 (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) ≥98% 13575-86-5 5mg $40 2024-03-01 Buy
Cayman Chemical 23866 (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) ≥98% 13575-86-5 10mg $74 2024-03-01 Buy
Cayman Chemical 23866 (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) ≥98% 13575-86-5 25mg $177 2024-03-01 Buy
Cayman Chemical 23866 (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) ≥98% 13575-86-5 50mg $311 2024-03-01 Buy
TRC A610023 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthaleneHydrobromide 13575-86-5 1mg $90 2021-12-16 Buy
Product number Packaging Price Buy
23866 5mg $40 Buy
23866 10mg $74 Buy
23866 25mg $177 Buy
23866 50mg $311 Buy
A610023 1mg $90 Buy

6-aminotetralin-2,3-diol Chemical Properties,Uses,Production

Description

6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2? Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4

Uses

(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide is a dopamine receptor agonist in Tribolium castaneum.

References

1) List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895 2) Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629 3) Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; Curr. J. Pharmacol. Exp. Ther., 268 417 4) Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591

13917-16-3
13575-86-5
Synthesis of 6-aminotetralin-2,3-diol from 6,7-Dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine hydrochloride

6-aminotetralin-2,3-diol Preparation Products And Raw materials

Raw materials

Preparation Products

6-aminotetralin-2,3-diol Suppliers

Global( 20)Suppliers
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Creative Enzymes
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Aladdin Scientific
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
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Henan CoreyChem Co., Ltd 0371-86658258 info@coreychem.com China 10457 58
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Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
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Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
6-aminotetralin-2,3-diol 6-Amino-5,6,7,8-tetrahydro-2,3-naphthalenediolhydrobromide ADTN hydrobromide 6,7-Dihydroxy-2-aminotetraline hydrobromide (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthaleneHydrobromide Aminotetraline hydrobromide, 6,7-Dihydroxy-2- 13575-86-5 BrHC10H13NO2 Dopamine