ChemicalBook >> CAS DataBase List >>ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
- CAS No.
- 37178-37-3
- Chemical Name:
- ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
- Synonyms
- TV-1203;L-Dopa-Et;O-Ethyl-DOPA;L-DOPA Ethyl Ester;Levodopa ethyl ester;Levodopa Impurity 27;L-Dopa ethyl ester >=98% (HPLC);3-Hydroxy-L-tyrosine ethyl ester;L-Tyrosine, 3-hydroxy-, ethyl ester;3,4-Dihydroxy-L-phenylalanine ethyl ester
- CBNumber:
- CB61568662
- Molecular Formula:
- C11H15NO4
- Molecular Weight:
- 225.24
- MDL Number:
- MFCD00871210
- MOL File:
- 37178-37-3.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:19
| Boiling point | 394.2±37.0 °C(Predicted) |
|---|---|
| Density | 1.278±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: ≥12mg/mL at warmed to 60°C |
| pka | 9.67±0.20(Predicted) |
| form | powder |
| color | white to tan |
| FDA UNII | 895X917GYE |
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0091 | L-Dopa ethyl ester ≥98% (HPLC) | 37178-37-3 | 5mg | $131 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0091 | L-Dopa ethyl ester ≥98% (HPLC) | 37178-37-3 | 25mg | $526 | 2024-03-01 | Buy |
| ChemScene | CS-0063515 | Etilevodopa >97.0% | 37178-37-3 | 10mg | $670 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD171004 | L-Dopa ethyl ester | 37178-37-3 | 25mg | $750 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD171004 | L-Dopa ethyl ester | 37178-37-3 | 1mg | $85 | 2021-12-16 | Buy |
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Chemical Properties,Uses,Production
Uses
Antiparkisonian.
Uses
L-Dopa ethyl ester has been used to study the protective effects of piperlongumine (PLG) on rotenone-induced Parkinson disease (PD).
Definition
ChEBI: Etilevodopa is a tyrosine derivative.
Biochem/physiol Actions
L-Dopa ethyl ester is a prodrug of levodopa that has greater gastric solubility. The drug is rapidly hydrolyzed to levodopa by nonspecific esterases in the gastrointestinal tract. L-Dopa ethyl ester (etilevodopa)-carbidopa treatment was well tolerated but did not demonstrate better efficacy compared with standard levodopa-carbidopa treatment. L-Dopa ethyl ester should have a significant brain penetration following an administration by injection.
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Preparation Products And Raw materials
Raw materials
Preparation Products
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Suppliers
Global( 21)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| LinkChem Co.,Ltd. | 021-021-58950110 13124863828 | sales@linkchem.cn | China | 3000 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 | amber@biochempartner.com | China | 3063 | 58 |
| Chengdu Feibai Pharmaceutical Co., Ltd. | 028-84641798 18782128315 | 3302391190@qq.com | China | 9853 | 55 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
O-Ethyl-DOPA
TV-1203
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
L-DOPA Ethyl Ester
2(S)-Amino-3-(3,4-dihydroxyphenyl)propionic acid ethyl ester
3,4-Dihydroxy-L-phenylalanine ethyl ester
3-Hydroxy-L-tyrosine ethyl ester
L-Dopa-Et
Levodopa ethyl ester
L-Tyrosine, 3-hydroxy-, ethyl ester
L-Dopa ethyl ester >=98% (HPLC)
Levodopa Impurity 27
37178-37-3