ChemicalBook >> CAS DataBase List >>Reversan
Reversan
- CAS No.
- 313397-13-6
- Chemical Name:
- Reversan
- Synonyms
- CBLC4H10;Reversan;N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-;5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide;ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan
- CBNumber:
- CB61883226
- Molecular Formula:
- C26H27N5O2
- Molecular Weight:
- 441.52
- MDL Number:
- MFCD01528184
- MOL File:
- 313397-13-6.mol
Last updated:2023-06-30 15:45:59
Reversan price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0173 | Reversan ≥98% (HPLC) | 313397-13-6 | 5mg | $129 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0173 | Reversan ≥98% (HPLC) | 313397-13-6 | 25mg | $519 | 2024-03-01 | Buy |
| Tocris | 3722 | Reversan ≥99%(HPLC) | 313397-13-6 | 50 | $952 | 2021-12-16 | Buy |
| Tocris | 3722 | Reversan ≥99%(HPLC) | 313397-13-6 | 10 | $227 | 2021-12-16 | Buy |
| Usbiological | 256447 | Reversan | 313397-13-6 | 10mg | $480 | 2021-12-16 | Buy |
Reversan Chemical Properties,Uses,Production
Uses
Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma.
Biological Activity
Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin , vincristine and etoposide by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo . Displays at activity on MRP2, MRP3, MRP5 and MRP5 transporters.
storage
Store at -20°C
Reversan Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8619164747840 | 13119157289@163.com | China | 2971 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18117592386 | 3007522982@qq.com | China | 52712 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55591 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Reversan
CBLC4H10
5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-
ReversanQ: What is
Reversan Q: What is the CAS Number of
Reversan Q: What is the storage condition of
Reversan Q: What are the applications of
Reversan
313397-13-6
C26H27N5O2
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals