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AC-DEVD-PNA

CAS No.
189950-66-1
Chemical Name:
AC-DEVD-PNA
Synonyms
AC-DEVD-P;AC-DEVD-PNA;(2S,5S,8S,11S);ACETYL-DEVD-PNA;AC-DEVD-PNA?, >98%;-11-(carboxymethyl);-8-(2-carboxyethyl);AC-ASP-GLU-VAL-ASP-PNA;-2-(2-Amino-2-oxoethyl);N-Ac-Asp-Glu-Val-Asp-pNA
CBNumber:
CB6203612
Molecular Formula:
C26H34N6O13
Molecular Weight:
638.58
MDL Number:
MFCD00792707
MOL File:
189950-66-1.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:14

AC-DEVD-PNA Properties

Boiling point 1191.1±65.0 °C(Predicted)
Density 1.448±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form powder
pka 2.97±0.10(Predicted)
color white
Water Solubility Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).
Stability Hygroscopic

SAFETY

Risk and Safety Statements

WGK Germany  3

AC-DEVD-PNA price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A2559 N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide ≥97% (HPLC), powder 189950-66-1 5mg $203 2024-03-01 Buy
Alfa Aesar J65878 N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide 189950-66-1 25mg $321 2023-06-20 Buy
Cayman Chemical 14460 Ac-DEVD-pNA ≥95% 189950-66-1 1mg $25 2021-12-16 Buy
Cayman Chemical 14460 Ac-DEVD-pNA ≥95% 189950-66-1 5mg $69 2021-12-16 Buy
Cayman Chemical 14460 Ac-DEVD-pNA ≥95% 189950-66-1 10mg $125 2021-12-16 Buy
Product number Packaging Price Buy
A2559 5mg $203 Buy
J65878 25mg $321 Buy
14460 1mg $25 Buy
14460 5mg $69 Buy
14460 10mg $125 Buy

AC-DEVD-PNA Chemical Properties,Uses,Production

Uses

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32.

Uses

N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase.

Uses

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

Biochem/physiol Actions

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

AC-DEVD-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 111)Suppliers
Supplier Tel Email Country ProdList Advantage
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30256 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58

AC-DEVD-PNA Spectrum

CASPASE 3 (APOPAIN) SUBSTRATE 1, CHROMOGENIC CASPASE-3 SUBSTRATE VIII, WATER-SOLUBLE, COLORIMETRIC CASPASE 3/CPP32 CHROMOGENIC SUBSTRATE CASPASE-3 SUBSTRATE (CHROMOGENIC) CASPASE-3 SUBSTRATE I, COLORIMETRIC CHROMOGENIC CASPASE 3 SUBSTRATE AC-DEVD-PNA AC-ASP-GLU-VAL-ASP-PARANITROANILIDE AC-ASP-GLU-VAL-ASP-PNA AC-DEVD-PNA ACETYL-DEVD-PNA ACETYL-ASP-GLU-VAL-ASP-(P-NITROANILIDE) N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE PNA AC-ASP-GLU-VAL-ASP-P-NITROANILIDE AC-ASP-GLU-VAL-ASP-PNA: AC-DEVD-PNA (2S,5S,8S,11S) -11-(carboxymethyl) -2-(2-Amino-2-oxoethyl) -4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid -5-isopropyl-3-(4-nitrophenyl) -8-(2-carboxyethyl) N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine Ac-DEVD-pNA,Ac-Asp-Glu-Val-Asp-pNA,Ac-Asp-Glu-Val-Asp-p-nitroanilide Ac-DEVD-pNA(Caspase-3 Substrate) Ac-DEVD-pNA,N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide, >98% AC-DEVD-PNA?, >98% L-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)- (9CI) AC-DEVD-P N-Acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine Ac-DEVD-pNA,N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide N-Ac-Asp-Glu-Val-Asp-pNA 189950-66-1 C26H34N6O13 Substrates BioChemical Caspase 3 Caspases Cell Biology Cell Signaling and Neuroscience Apoptosis and Cell Cycle Caspase/Related Products Pepetides peptide