ANTI-PHOSPHO-STAT3 (PTYR705)
- CAS No.
- Chemical Name:
- ANTI-PHOSPHO-STAT3 (PTYR705)
- Synonyms
- ANTI-STAT3 (PY705);ANTI-PHOSPHO-STAT3 (Y705);ANTI-PHOSPHO-STAT3 (PTYR705);ANTI-STAT3 (PTYR705) MOUSE MAB;ANTI-ACTIVATED STAT3 (TYR 705);ANTI-STAT3 (PHOSPHORYLATED) (PTYR705);Anti-HIES antibody produced in rabbit;Anti-APRF antibody produced in rabbit;Anti-MGC16063 antibody produced in rabbit;Anti-FLJ20882 antibody produced in rabbit
- CBNumber:
- CB6206002
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02097172
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Safety Statements | 23-24/25 |
|---|---|
| WGK Germany | 1 |
ANTI-PHOSPHO-STAT3 (PTYR705) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4504541 | Anti-phospho-STAT3 (pTyr705) antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300327 | Anti-STAT3 (Ab-727) antibody produced in rabbit affinity isolated antibody | 100μg | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300033 | Anti-phospho-STAT3 (pTyr705) antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy | |
| Sigma-Aldrich | S2690 | Anti-phospho-STAT3 (pTyr705) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution | 1vial | $753 | 2024-03-01 | Buy |
ANTI-PHOSPHO-STAT3 (PTYR705) Chemical Properties,Uses,Production
Uses
Anti-phospho-STAT3 (pTyr705) antibody produced in rabbit has been used in immunohistochemical staining and immunoblotting.
General Description
Signal transducer and activator of transcription 3 (STAT3) is a member of STAT family and it composed of 770 amino acids. The gene encoding protein consists of 24 exons and is extended over a length of 75170 bases on genomic DNA STAT3 is mapped on human chromosome 17q21.2. The protein is characterized with a conserved amino-terminal domain, a DNA-binding domain, an SH2 domain and a carboxy-terminal transactivation domain.
Biochem/physiol Actions
Signal transducer and activator of transcription 3 (STAT3) plays a vital role in various cellular responses such as induction of an acute-phase response in hepatoma cells, stimulation of proliferation in B lymphocytes, activation of terminal differentiation and growth arrest in monocytes, and regulation of the pluripotency of embryonic stem cells. Activated STAT3 has been involved in malignant transformation. STAT3 may be a key player in the pathogenesis of diverse human cancers which makes this molecule a prime target for novel therapies. Phospho-tyrosine residue 705 (Tyr705) Stat3 can be used as a potential marker for determining overall survival of node-negative breast cancer patients. Phosphorylated STAT3 might be involved in angiogenesis, anti-apoptosis and tumor progression.
ANTI-PHOSPHO-STAT3 (PTYR705) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-PHOSPHO-STAT3 (PTYR705) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |