Pristinamycin IA
- CAS No.
- 3131-03-1
- Chemical Name:
- Pristinamycin IA
- Synonyms
- PA 114B;NSC 92554;mikamycin B;MikaMycin IA;Ostreogrycin B;VirginiaMycin B;Streptogramin B;Pristinamycin IA;Pristinamycin ⅠA;PristinaMycin P 1
- CBNumber:
- CB62079233
- Molecular Formula:
- C45H54N8O10
- Molecular Weight:
- 866.96
- MDL Number:
- MFCD30489790
- MOL File:
- 3131-03-1.mol
| Melting point | 198° |
|---|---|
| alpha | D22 -57.5° (c = 0.25 in ethanol) |
| Boiling point | 780.3°C (rough estimate) |
| Density | 1.1881 (rough estimate) |
| refractive index | 1.6910 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | pKa 7.20±0.05(H2O,t =25,I=0.2(LiClO4)) (Uncertain) |
| color | Pale Yellow |
| FDA UNII | V50XJ0NC3I |
Pristinamycin IA price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28086 | Streptogramin B | 3131-03-1 | 1mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 28086 | Streptogramin B | 3131-03-1 | 25mg | $1075 | 2024-03-01 | Buy |
| Cayman Chemical | 28086 | Streptogramin B | 3131-03-1 | 5mg | $253 | 2024-03-01 | Buy |
| Cayman Chemical | 28086 | Streptogramin B | 3131-03-1 | 10mg | $468 | 2024-03-01 | Buy |
| Usbiological | V2122-82A | Virginiamycin B | 3131-03-1 | 5mg | $513 | 2021-12-16 | Buy |
Pristinamycin IA Chemical Properties,Uses,Production
Uses
Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a syngergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Viriginiamycin B acts a syngergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.
Uses
One of the two major components of Pristinamycin (Pristinamycin IA and Pristinamycin IIA (or Virginiamycin M1-V673810).
Definition
ChEBI: A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organis s including methicillin-resistant Staphylococcus aureus.
Contact allergens
Pristinamycin is a systemic antibiotic of the synergistins/ streptogramins class, composed of two subunits: pristinamycin IA and pristinamycin IIA. It induces several types of drug reactions such as maculo-papular exanthema, systemic dermatitis, or acute generalized exanthematous pustulosis. Some patients have been previously skin-sensitized by virginiamycin. Crossreactivity is expected to virginiamycin and to the associated dalfopristin and quinupristin.
Pristinamycin IA Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8018 | 62 |