ChemicalBook >> CAS DataBase List >>8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate structure

CAS No.: 264622-58-4

Chemical Name:: 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate

Synonyms: MRS 1754 hydrate;MRS1754;MRS-1754;MRS 1754;Adenosine Receptor,MRS-1754,Inhibitor,MRS 1754,P1 receptor,MRS1754,inhibit;N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide;8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate;N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetaMide;N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide;AcetaMide,N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-;AcetaMide, N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-

CBNumber:: CB62098696

Molecular Formula:: C26H26N6O4

Molecular Weight:: 486.52

MDL Number:: MFCD09971130

MOL File:: 264622-58-4.mol

MSDS File:: SDS

Last updated:2023-09-04 15:51:00

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8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Properties

Density	1.38±0.1 g/cm3(Predicted)
storage temp.	room temp
solubility	DMSO: soluble >10mg/mL
pka	8.24±0.70(Predicted)
form	solid
color	off-white
FDA UNII	7E435V2DAH

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314-H290

Precautionary statements

P501-P260-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405

Safety Statements

22-24/25

WGK Germany

NFPA 704

	0
2		0

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M6316	MRS 1754 hydrate ≥98% (HPLC), solid	264622-58-4	5mg	$265	2024-03-01	Buy
Sigma-Aldrich	M6316	MRS 1754 hydrate ≥98% (HPLC), solid	264622-58-4	25mg	$837	2024-03-01	Buy
TRC	M750243	MRS1754	264622-58-4	1mg	$115	2021-12-16	Buy
ChemScene	CS-0003210	MRS1754 98.31%	264622-58-4	5mg	$140	2021-12-16	Buy
ChemScene	CS-0003210	MRS1754 98.31%	264622-58-4	10mg	$190	2021-12-16	Buy

Product number	Packaging	Price	Buy
M6316	5mg	$265	Buy
M6316	25mg	$837	Buy
M750243	1mg	$115	Buy
CS-0003210	5mg	$140	Buy
CS-0003210	10mg	$190	Buy

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Chemical Properties,Uses,Production

Uses

MRS 1754 acts as an adenosine receptor antagonist which displays bronchospasmolytic activity, applicable to treatments involving respiratory disorders.

Definition

ChEBI: N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide is an oxopurine.

Biological Activity

Selective adenosine A 2B receptor antagonist (K i values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA 2B , rA 1 , hA 1 , hA 2A , hA 3 and rA 2A receptors respectively).

Biochem/physiol Actions

MRS 1754 hydrate is a p-cyanoanilide xanthine derivative. It might act as a potential anti-asthmatic drug.

storage

Desiccate at RT

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	6011	61
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10269	58
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9442	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60

Supplier	Advantage
TargetMol Chemicals Inc.	58
LEAP CHEM CO., LTD.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chembest Research Laboratories Limited	61
Hangzhou Sage Chemical Co., Ltd.	58
Shanghai Topbiochem Technology Co., Ltd	58
EMMX Biotechnology LLC	60

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Spectrum

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate(264622-58-4)¹HNMR

264622-58-4(8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate)Related Search:

1,3-DIETHYL-8-PHENYLXANTHINE 1,3-DIPROPYL-8-PHENYLXANTHINE 8-PHENYLTHEOPHYLLINE 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate

8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate MRS 1754 hydrate AcetaMide, N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]- N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetaMide AcetaMide,N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]- N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide MRS1754;MRS-1754;MRS 1754 Adenosine Receptor,MRS-1754,Inhibitor,MRS 1754,P1 receptor,MRS1754,inhibit 264622-58-4