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2-Bromo-6-fluorobenzonitrile

CAS No.
79544-27-7
Chemical Name:
2-Bromo-6-fluorobenzonitrile
Synonyms
2-FLUORO-6-BROMOBENZONITRILE;6-BROMO-2-FLUOROBENZONITRILE;2-BROM;2-Bromo-6-fluorobenzon;2- fluoro-6-bromoxynil;2-Bromo-6-fluorobenzotrile;2-BROMO-6-FLUOROBENZONITRILE;3-bromo-2-cyanofluorobenzene;2-Cyano-3-Fluoro-1-broMobenzene;Benzonitrile, 2-bromo-6-fluoro-
CBNumber:
CB6216595
Molecular Formula:
C7H3BrFN
Molecular Weight:
200.01
MDL Number:
MFCD06797753
MOL File:
79544-27-7.mol
MSDS File:
SDS
Last updated:2023-04-27 16:27:43

2-Bromo-6-fluorobenzonitrile Properties

Melting point 60-61
Boiling point 254.6±25.0 °C(Predicted)
Density 1.69±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form Solid
color White to brown
InChIKey IELGUZKHALDFOO-UHFFFAOYSA-N
CAS DataBase Reference 79544-27-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H302-H315-H319-H335-H312-H332
Precautionary statements  P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501-P261-P305+P351+P338-P304+P340-P405-P501a
Hazard Codes  T,Xi,Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
Hazard Note  Toxic
HazardClass  IRRITANT-HARMFUL
HazardClass  6.1
HS Code  2926907090
NFPA 704
1
2 0

2-Bromo-6-fluorobenzonitrile price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B3183 2-Bromo-6-fluorobenzonitrile >97.0%(GC) 79544-27-7 5g $66 2024-03-01 Buy
Alfa Aesar H61498 2-Bromo-6-fluorobenzonitrile, 97% 79544-27-7 5g $36.7 2021-12-16 Buy
Alfa Aesar H61498 2-Bromo-6-fluorobenzonitrile, 97% 79544-27-7 25g $147 2021-12-16 Buy
TRC B692023 2-Bromo-6-fluorobenzonitrile 79544-27-7 500mg $45 2021-12-16 Buy
Matrix Scientific 018273 2-Bromo-6-fluorobenzonitrile 98% 79544-27-7 25g $49 2021-12-16 Buy
Product number Packaging Price Buy
B3183 5g $66 Buy
H61498 5g $36.7 Buy
H61498 25g $147 Buy
B692023 500mg $45 Buy
018273 25g $49 Buy

2-Bromo-6-fluorobenzonitrile Chemical Properties,Uses,Production

Chemical Properties

Off-white crystalline

Uses

2-Bromo-6-fluorobenzonitrile is used as an initial raw material in the synthesis of  2-bromo-6-fluorobenzoic acid.

Synthesis

2-Amino-6-fluorobenzonitrile (18.0 g, 132 mmol) was dissolved in hot 1,4-dioxane (20 ml), 48% hydrobromic acid (200 ml) was added and the mixture cooled to 0°C before dropwise addition of sodium nitrite (10.5 g, 152 mmol) in water (20 ml) over 1.5 h. The resulting mixture was stirred at 0°C for 1.5 h then poured onto a cooled (0°C) solution of copper(I) bromide (56.8 g, 396 mmol) in 48% hydrobromic acid (50 ml). The solution was stirred at 0°C for 15 min then heated at 50°C for 20 min. The mixture was cooled to ambient temperature, diluted with water (1200 ml) and extracted with ethyl acetate (2 x 400 ml). The combined organics were washed with 10% aqueous ammonia solution (400 ml), water (400 ml) and brine (500 ml), dried over anhydrous magnesium sulfate, filtered and evaporated to give an orange oil. Purification by chromatography on silica 5 gel eluting with isohexane on a gradient of ethyl acetate (2-4%) gave 2-bromo-6-fluorobenzonitrile. White solid, yield (18.5 g, 70%). δH (400 MHz, CDCl3) 7.17-7.23 (1H, ddd, J 8, 8 and 1), 7.44-7.52 (2H, m).
synthesis of 2-Bromo-6-fluorobenzonitrile

360575-28-6
79544-27-7
Synthesis of 2-Bromo-6-fluorobenzonitrile from 2-Bromo-6-fluorobenzaldehyde

2-Bromo-6-fluorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 210)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Anxuan Chemical Co., Ltd
+86-0519-89882563 +86-18961279162 andy@anxuanchem.com China 4226 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
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Hubei xin bonus chemical co. LTD
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Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58

View Lastest Price from 2-Bromo-6-fluorobenzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-BROMO-6-FLUOROBENZONITRILE pictures 2023-02-16 2-BROMO-6-FLUOROBENZONITRILE
79544-27-7
US $0.00 / KG 1KG 98% 1MT Changzhou Anxuan Chemical Co., Ltd
2-BROMO-6-FLUOROBENZONITRILE pictures 2019-07-06 2-BROMO-6-FLUOROBENZONITRILE
79544-27-7
US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co
2-BROMO-6-FLUOROBENZONITRILE 2-Cyano-3-Fluoro-1-broMobenzene 3-bromo-2-cyanofluorobenzene 2- fluoro-6-bromoxynil 2-Bromo-6-fluorobenzotrile 2-Bromo-6-fluorobenzonitrile > Benzonitrile, 2-bromo-6-fluoro- 6-BROMO-2-FLUOROBENZONITRILE 2-FLUORO-6-BROMOBENZONITRILE 2-BROM 2-Bromo-6-fluorobenzon 79544-27-7 Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds Building Blocks C6 to C7 Fluorine series cyanide| alkyl bromide| alkyl Fluorine Aromatic Nitriles Nitrile C6 to C7 Cyanides/Nitriles Nitrogen Compounds