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3-Phenylpropionic acid

Description Preparation Uses
3-Phenylpropionic acid
3-Phenylpropionic acid
Chemical Name:
3-Phenylpropionic acid
NSC 9272;FEMA 2889;hydrocinnamic;BENZYLACETIC ACID;Hydrocinamic acid;3-Phenylpropionic;HYDROCINNAMIC ACID;RARECHEM AL BO 0168;Phenylpropionic aci;HYDROXYCINNAMIC ACID
Molecular Formula:
Formula Weight:
MOL File:

3-Phenylpropionic acid Properties

Melting point:
45-48 °C(lit.)
Boiling point:
280 °C(lit.)
1.071 g/mL at 25 °C(lit.)
refractive index 
1.5408 (estimate)
Flash point:
>230 °F
storage temp. 
ethanol: soluble50mg/mL, clear, colorless to faintly yellow
4.66(at 25℃)
Clear yellow to yellow-green
Water Solubility 
Soluble in water
CAS DataBase Reference
501-52-0(CAS DataBase Reference)
NIST Chemistry Reference
3-Phenylpropanoic acid(501-52-0)
EPA Substance Registry System
Benzenepropanoic acid(501-52-0)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-37/39-26
WGK Germany  3
RTECS  DA8600000
HS Code  29163900
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

3-Phenylpropionic acid price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 135232 Hydrocinnamic acid 99% 501-52-0 5g $17.5 2017-11-08 Buy
Sigma-Aldrich 135232 Hydrocinnamic acid 99% 501-52-0 100g $39 2017-11-08 Buy
TCI Chemical H0183 3-Phenylpropionic Acid >98.0%(GC)(T) 501-52-0 25g $21 2017-12-01 Buy
TCI Chemical H0183 3-Phenylpropionic Acid >98.0%(GC)(T) 501-52-0 100g $63 2017-12-01 Buy
Alfa Aesar A14908 3-Phenylpropionic acid, 99% 501-52-0 100g $43.2 2017-11-08 Buy

3-Phenylpropionic acid Chemical Properties,Uses,Production


3-Phenylpropionic acid is a carboxylic acid that belongs to the class of phenylpropanoids. Also referred as hydrocinnamic acid, the chemical is a white crystalline solid with a sweet fatty smell of rose musk cinnamon at room temperature. 3-Phenylpropionic acid is soluble in both water and alcohol. It is widely used in food additives, cosmetics, and pharmaceuticals.


Hydrogenation of cinnamic acid is used in the preparation of 3-Phenylpropionic acid. Initially, the chemical was prepared by reduction with sodium amalgam in water by electrolysis.


Food Industry
3-Phenylpropionic acid is utilized in the food industry as a preservative as well as to maintain the original quality of aroma of frozen foods. It is also used for flavoring and restoring original color to food. 3-Phenylpropionic acid is added to shelved foods to prevent microorganisms from deteriorating the food. It also acts as an antioxidant to prolong the life of foodstuff in shelves. 3-Phenylpropionic acid is also used as a food sweetener.
3-Phenylpropionic acid acts as an emulsifier as it can keep water and oil mixtures separated. 3-Phenylpropionic acid can be added in food for technological reasons in wide range such as processing, manufacturing, packaging, treatment, transportation, and storage.
3-Phenylpropionic acid is used in beautifying products such as bath gels, detergent powders, and fabric softeners as it gives a floral scent. It is also used as a flavour for mouthwashes and toothpastes.

Chemical Properties

white to off-white crystalline mass, powder or crystals and/or chunk


Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.


Hydrocinnamic acid was used in the synthesis of three medium-chain acyl-Coenzyme A′s i.e. 3-phenylpropionyl-CoA from mixed anhydrides of fatty acids.


ChEBI: A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group.

Purification Methods

Crystallise the acid from *benzene, CHCl3 or pet ether (b 40-60o). Dry it in a vacuum. [Beilstein 9 H 508.]

3-Phenylpropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3-Phenylpropionic acid Suppliers

Global( 302)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3218 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22144 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20803 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32765 55
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30308 84
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40399 62
Arden pharmaceutical &chemical Co., Ltd +86-(0)533-3595900 13793319233
+86-(0)533-3595900 China 670 61
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 China 22909 81
Beijing dtftchem Technology Co., Ltd. 13651141086; 86(10)60275028、60275820
86 (10) 60270825 China 1443 62

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